CD58 (Pnh Marker)

CD58 is a protein present on the surface of white blood cells. The CD58 (Pnh Marker) panel test is a flow cytometry-based diagnostic test that measures the expression of CD58 on the surface of red blood cells.

It helps to diagnose paroxysmal nocturnal hemoglobinuria (PNH), which is a rare blood disorder that causes the breakdown of red blood cells leading to anaemia, blood clots, and other complications.

Symptoms

PNH is a rare blood disorder that can be difficult to diagnose as its symptoms overlap with several other conditions. The following are some common symptoms associated with PNH:
- Fatigue
- Shortness of breath
- Chest pain
- Blood clots
- Abdominal pain
- Difficulty swallowing
- Headache
- Back pain
- Dark urine

Test Procedure

The CD58 (Pnh Marker) panel test requires a bone marrow sample. The bone marrow sample is collected using a needle that is inserted into the pelvic or breastbone. The process can be painful, but it is generally safe and has few risks. After the sample is collected, it is sent to the lab for analysis.

The CD58 (Pnh Marker) panel test is a flow cytometry-based test that measures the expression of CD58 on the surface of red blood cells. During the test, a small amount of bone marrow samples is mixed with fluorescently labelled antibodies specific to different cell markers. The mixture is then analysed using a flow cytometer, which measures the fluorescence intensity of each cell. Based on the intensity of fluorescence, the number of CD58-positive cells is determined.

Treatment

There is no cure for PNH. There are certain treatments that can help manage the symptoms and improve the quality of life for patients. The treatment options may include blood transfusions, anticoagulant therapy, bone marrow transplant, and medication.

Booking a CD58 (Pnh Marker) Panel on Apollo 24|7

Booking a CD58 (Pnh Marker) panel on Apollo 24|7 is easy and convenient. Simply visit the Apollo 24|7 website and select the “Lab Tests” option from the menu. From there, you can search for the test by name and select your preferred location and time slot. Results for the CD58 (Pnh Marker) panel are typically available within 72 hours, allowing for prompt diagnosis and treatment if necessary.

Benefits of Early Diagnosis

Early diagnosis of PNH through the CD58 (Pnh Marker) panel can be highly beneficial. Some advantages of early diagnosis include:
1. Accurate diagnosis and treatment
2. Improved quality of life
3. Reduced risk of complications
4. Better management of symptoms

If you suspect that you have PNH or have been diagnosed with aplastic anaemia or myelodysplastic syndrome, it is recommended that you get tested for PNH. You can book the CD58 (Pnh Marker) panel test on Apollo 24|7 at an affordable price. Early diagnosis and treatment can help manage the symptoms and improve the quality of life for patients with PNH. Additionally, individuals who opt for early diagnosis can also benefit from the accuracy of the method and avoid complications associated with late diagnosis.