apollo
  • Male
  • 16 Years
  • 29/01/2025

Can I take melatonin to help me sleep if I'm already prescribed a 25 mg amitriptyline pill daily to reduce my headache frequency? I'm just worried if there's any interaction or issues mixing the two.

Doctor 1

Answered by 1 Apollo Doctors

Melatonin and amitryptiline has a potential for interaction so it should be used very carefully as they both increase sedation and drowsiness. The medications should not be had unless directed by your treating doctor. If you develop any problem visit the ER at the earliest.

Dr. Kareemulla Suggests...

Consult a Neurologist

Answered 04/07/2025

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  1. Potential Interactions: Combining melatonin with amitriptyline may increase drowsiness or sedation. You might feel more sleepy or tired.

  2. Safety in Teens: At 16, consult your healthcare provider before adding melatonin. They can evaluate your headache treatment and sleep needs.

  3. Monitoring: If approved, start with a low dose and monitor for side effects or changes in how you feel.

  4. Alternative Approaches: Consider improving sleep hygiene, like maintaining regular sleep schedules and reducing screen time before bed.

Summary: Consult your doctor to ensure melatonin is safe and appropriate with your current medication.

Answered 20/08/2025

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Disclaimer: Answers on Apollo 247 are not intended to replace your doctor advice. Always seek help of a professional doctor in case of an medical emergency or ailment.