Diabetes affects nerves which reduce one's sensitivity to pain from wound leading to repetitive traumas, wounds can get infected which may not heal fastly due to reduced blood supply. Sometimes, a bad infection never heals. The infection might lead to gangrene and amputation.
Redness, swelling, and itching at the injection site,changes in the feel of your skin, skin thickening (fat build-up), or a little depression in the skin (fat breakdown) weight gain are possible side effects
Both oral medicines and insulin are good at treating Diabetes, each having it's own benefits and side effects.
Diabetes mellitus causes blood vessel damage, vascular remodelling leading to increased peripheral artery resistance. Also, body fluid volume increases in response to insulin resistance-induced hyperinsulinemia and hyperglycemia. Both increased peripheral vascular resistance and body fluid volume lead to increase in systemic blood pressure causing Hypertension.
Regaining weight must be under dietician observation with balanced nutritious meals.