I'm really worried about my mom. She's been on Human Mixtard insulin with 20 units in the morning and 15 at night, but she's been having these really scary hypoglycemic episodes. Recently, her kidney issues were also pointed out by a distant doctor. At a nearby hospital, they suggested switching her to Ryzodeg and changing her dose to 10 units. But ever since that change, her blood sugar has skyrocketed to 480 at night before insulin and dinner, and her fasting level is at 280. I'm really anxious about these high levels. What can I do to help get her sugar levels under control? Any advice would be really appreciated.

Answered by 1 Apollo Doctors

Dr Dr Khaleel Ur Rahim

General Practitioner

MBBS
1+ Yrs

Consult Now

Ryzodeg and Human Mixtard are both insulin therapies, but they have different properties:

Ryzodeg

Fast-acting and long-acting insulin analogue: Ryzodeg contains insulin degludec and insulin aspart.

Faster onset and longer duration: Ryzodeg starts working within 30 minutes and lasts for up to 24 hours.

More flexible dosing: Ryzodeg can be administered at any time of day, regardless of meals.

Human Mixtard

Intermediate-acting human insulin: Human Mixtard contains human insulin suspension.

Slower onset and shorter duration: Human Mixtard starts working within 1-2 hours and lasts for up to 12 hours.

More rigid dosing schedule: Human Mixtard typically requires a more structured dosing schedule, tied to meals.

Considering your mother's:

Concurrent hypoglycemia: Ryzodeg's faster onset and longer duration may help reduce hypoglycemic episodes.

Kidney failure: Ryzodeg may be a better option, as it has a lower risk of accumulation and toxicity in patients with renal impairment.

However, the recent blood sugar readings (480 at night and 280 fasting) indicate that the current Ryzodeg dosage (10-0-10 units) may not be effective.

Recommendations

Consult her doctor: Discuss the recent blood sugar readings and adjust the Ryzodeg dosage accordingly.

Monitor blood sugar levels: Regularly track her blood sugar levels to ensure the new dosage is effective.

Consider additional therapies: If blood sugar levels remain uncontrolled, her doctor may recommend additional therapies, such as oral medications or other insulin types.

Dr. Dr Khaleel Suggests...

Consult a Endocrinologist

Find a Endocrinologist

Answered 04/07/2025

More Endocrinology Health Queries

View all

I'm a 19-year-old female with a small bust and I'm curious if estrogen pills actually work to increase breast size. I've seen articles saying they do but I'm not sure about their safety. Can you recommend any specific ones if they're effective and what side effects should I watch out for? I'd prefer not to get surgery and I'm 54 kg and 43 kg so I want something natural.

U first need to visit us for an examination post which we will be able to advise you on this.

Answered by 1 Apollo Doctors

What causes blood sugar to rise without eating?

Missing morning meal, caffeine can cause insulin to function less efficiently. Hence blood sugars rise. Some other triggers which can rise blood sugar include stress, excess usage of artifical sweetners, loosing sleep, dehydration, some nasal sprays and dawn phenomenon (People have a surge in hormones early in the morning whether they have diabetes or not. For people with diabetes, blood sugar can spike).

Answered by 1 Apollo Doctors

I'm a bit worried about my mom since she's diabetic. If she ever needs it, can she take ORS safely without any issues? With everything so uncertain these days, I'm just trying to be cautious.

Yes, it is generally safe for your mother to take ORS if needed, as it helps to rehydrate and replenish lost electrolytes. However, since she is diabetic, it's important to choose an ORS with low sugar content and monitor her blood sugar levels closely during use. Always consult her doctor for personalized advice.

Answered by 1 Apollo Doctors