What is the genetic basis of sickle cell anemia?

Answered by 1 Apollo Doctors

Dr Hema Pratima

General Practitioner

MBBS
9+ Yrs

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Sickle cell disease (SCD) is a genetic disorder caused by a mutation in both copies of a person's HBB gene. This gene encodes a component of hemoglobin, the oxygen carrying protein in red blood cells. The mutation causes hemoglobin molecules to stick together, creating sickle-shaped red blood cells

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