What would happen if someone took 10 Dolo 650mg tablets all at once? Is it really dangerous enough to cause death, and what other side effects should I be worried about?

Dr Kareemulla Shaik

General Practitioner

• MBBS
• 0+ Yrs

Consult Now

Taking 10 Dolo 650 mg tablets (total 6,500 mg of paracetamol) at once is very dangerous and potentially life-threatening. Here's what happens:

🚨 Why It's Dangerous: Liver Toxicity: Paracetamol in high doses overwhelms the liver, leading to acute liver failure.

Fatal Dose: A single dose above 7,000–10,000 mg can be lethal, especially without treatment.

⚠️ Symptoms to Watch For: First 24 hours:

Nausea, vomiting

Sweating, general discomfort

Pale skin

24–72 hours:

Liver damage signs begin: right upper belly pain, dark urine, yellowing skin (jaundice)

72–96 hours:

Peak liver failure: confusion, bleeding, low blood sugar, coma or death

🆘 What to Do: Immediate ER visit is critical.

Activated charcoal may be given early.

Antidote: N-acetylcysteine (NAC), most effective within 8 hours of overdose.

Bottom line: Yes, taking 10 tablets is potentially deadly. Immediate medical attention can save life and liver. Never delay if overdose is suspected.

Answered 04/07/2025