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All About Breast Biopsy

Learn all about breast biopsies, including their types, procedures, preparation, risks, results, and recovery tips. Empower yourself with clear, easy-to-understand information to navigate this important diagnostic step with confidence.

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Last updated on 3rd Jul, 2025

A breast biopsy is a procedure in which a sample of breast tissue is removed using a biopsy needle or through surgery. This sample is then examined by a pathologist to check if there are signs of breast cancer or other conditions.

A breast biopsy is the only way to diagnose whether an area in the breast is cancerous. Healthcare providers may recommend this procedure to confirm or exclude the possibility of breast cancer.

This article will explore the breast biopsy procedure, its types, and what to expect during the process.

Types of Breast Biopsies

There are different types of breast biopsies. The choice of procedure depends on the size and location of the lump or area of concern.

  • Fine Needle Aspiration (FNA) Biopsy: A very thin needle is inserted into the lump or area of concern to remove a small sample of fluid or tissue. This method requires no incision and is often used to determine if the area is a fluid-filled cyst or a solid lump.

  • Core Needle Biopsy: A larger needle is used to take small tissue samples, called cores, from the lump or area of concern. Like FNA, this procedure does not require a cut.

  • Open (Surgical) Biopsy: This involves making a small incision in the breast to remove part or all of the lump. If the lump is small, deep, or hard to locate, a technique called wire localization may be used. A thin needle with a wire is inserted into the breast, guided by X-ray images, to mark the area for the surgeon to follow.

How to Prepare for a Breast Biopsy?

Preparing for a breast biopsy involves sharing essential details with the healthcare provider, surgeon, or radiologist. A patient should inform the medical team about:

  • Pregnancy or the possibility of being pregnant.

  • Use of blood-thinning medications, as adjustments, may be necessary to reduce bleeding or bruising risks.

  • Regular intake of aspirin or herbal supplements.

  • Existing medical conditions or recent surgeries.

  • Any allergies, particularly to anaesthesia.

This information ensures a safe and smooth biopsy process.

On the day of the biopsy:

  • Eating normally is allowed before the procedure. If medications are needed, they can be taken with a small sip of water.  

  • Wash the underarm area and breasts with soap and water, avoiding perfumes or deodorants.  

  • Wearing a snug bra, such as a sports bra, is recommended for support after the procedure.  

  • The technologist will confirm identity and exam details.  

  • There will be an opportunity to discuss the procedure with the radiologist and provide consent.  

The Procedure of a Breast Biopsy

Most breast biopsy procedures follow a few general steps. Here’s what would happen:

  • There will be a use of imaging or material guidance

  • A small incision will be made

  • A tissue from the breast area will be extracted 

  • The healthcare provider will place biopsy markers

  • At the end the incision will be closed 

  • Then, the sample will be sent for examination

Anaesthesia and Pain Management

For fine needle aspiration or core needle biopsies, a local anaesthetic is typically used. The area around the biopsy site is numbed with an injection to ensure no pain is felt. The patient remains awake but comfortable.  
For a surgical biopsy (excisional breast biopsy), general anaesthesia may be recommended, putting the individual asleep or unconscious. In some cases, a combination of local anaesthesia and sedation is used to help the person relax while preventing pain. 
These measures ensure the biopsy is as comfortable and pain-free as possible.

Risks and Complications

Breast biopsies are usually minimally invasive. However, there are some side effects of the procedure, such as:

  • Bruising

  • Bleeding

  • Swelling

  • Pain or soreness

  • Infection

Rare complications can happen but are extremely uncommon. These include:

  • Collapsed lung (pneumothorax)

  • Blood collects between the chest wall and lungs (hemothorax)

  • A combination of both a collapsed lung and blood in the chest (hemopneumothorax)

Understanding the Results

A breast biopsy report includes various terms that can feel overwhelming, but healthcare providers take time to explain them clearly. Patients should feel comfortable asking questions to understand their results better.

Typically, the results may indicate whether the sample contains pre-cancer cells, cancer cells or any other abnormal cells.

If a surgical biopsy was performed to remove a lump or tumour, the report provides details about the tumour’s type, grade, and receptor status. It also describes the surrounding tissue, known as the margin.

For cancerous tumours, the margin information helps determine if the cancer has been fully removed. Key terms related to margins include:

  • Positive margin: Cancer cells are present in the margin, meaning the cancer may not have been fully removed. Further surgery is often recommended.

  • Negative or clear margin: No cancer cells are found in the margin, indicating the cancer is surrounded by normal tissue.

  • Close margin: Cancer cells are near the edge of the margin but not on it. Additional surgery may be needed in this case.

Post-Biopsy Care

After a breast biopsy, proper care can help with healing and comfort. Patients can shower 24 hours after the procedure, but it’s important to remove the bandage first while keeping the Steri-Strips in place.

Swelling and bruising are common and usually resolve within a week. Applying an ice pack to the area for 10 to 15 minutes several times during the first 1 to 2 days can help reduce swelling.

A tight-fitting bra can provide extra support and help minimize discomfort. For three days following the biopsy, it’s advised to avoid:

  • Lifting objects heavier than 5 pounds (2.3 kilograms)

  • Strenuous activities like running or jogging

  • Bathing, swimming, or soaking the site in water. Showering is fine after 24 hours

For pain relief, acetaminophen can be used as directed. NSAIDs like ibuprofen or naproxen should be avoided as they may increase bleeding.

Blood-thinning medications, including aspirin, can typically be resumed the same day unless there’s significant bruising or bleeding. For any concerns, it’s always best to consult a healthcare provider.

Emotional Impact and Support

A breast biopsy can take an emotional toll, and it’s normal to feel anxious, scared, or overwhelmed. Taking care of emotional well-being is just as important as physical recovery.

Talking to trusted friends, family members, or professional counsellors can help ease the emotional burden. Sharing fears and concerns can make the process feel less isolating.

Connecting with others who have faced similar experiences can also provide comfort and perspective. Many hospitals and communities offer support groups for individuals undergoing breast biopsies or breast cancer treatment. These groups create a space to share, learn, and feel understood.

Conclusion 

A breast biopsy is a critical step in diagnosing breast conditions and ensuring timely treatment. While the process can feel overwhelming, understanding the procedure, preparing for it, and knowing what to expect can ease anxiety.

With proper care, most people recover well and receive valuable information about their health. Emotional support from loved ones, counsellors, or support groups can also provide comfort.

Remember, healthcare providers are there to guide and support patients every step of the way.

Consult Top Obstetrician and Gynaecologist

Dr. Mona Yadav, Obstetrician and Gynaecologist

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