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Understanding Buerger's Disease and Its Management

Buerger’s Disease affects blood flow to the limbs, often caused by smoking. Learn about its symptoms, causes, diagnosis, and how to manage and prevent this serious vascular condition.

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Written by Dr. M L Ezhilarasan

Reviewed by Dr. Md Yusuf Shareef MBBS

Last updated on 13th Jan, 2026

buergers

Buerger’s Disease, also known as Thromboangiitis Obliterans (TAO), is a rare but serious condition that affects blood vessels, primarily in the arms and legs. It causes inflammation and clotting in small and medium-sized arteries and veins, leading to reduced blood flow. Over time, this can result in pain, tissue damage, and even gangrene if left untreated.

While Buerger’s Disease is uncommon, it is strongly linked to tobacco use, particularly smoking. If you or someone you know smokes and experiences unusual pain or numbness in the hands or feet, it’s important to understand this condition and seek medical help early.

What Are the Symptoms of Buerger’s Disease?

Buerger’s Disease typically affects the hands and feet first, causing symptoms such as:

  • Pain and cramping in the legs or arms (especially during walking or using hands—called claudication)
  • Cold or numb fingers/toes
  • Skin color changes (pale, reddish, or bluish discoloration)
  • Sores or ulcers on fingers or toes that heal slowly
  • Weak or absent pulse in affected limbs
  • Severe cases may lead to gangrene (tissue death), requiring amputation

Symptoms often worsen with continued tobacco use, making quitting smoking the most crucial step in managing this disease.

What Causes Buerger’s Disease?

The exact cause is unknown, but tobacco use (smoking or chewing) is the biggest risk factor. Other possible contributors include:

  • Autoimmune response (where the body attacks its own blood vessels)
  • Genetic predisposition (more common in men under 45)
  • Chronic gum disease (some studies suggest a link)
  • Unlike other vascular diseases (like atherosclerosis), Buerger’s Disease is not caused by high cholesterol or diabetes, but smoking plays a central role.

How Is Buerger’s Disease Diagnosed?

Since symptoms resemble other conditions (like peripheral artery disease), doctors use a combination of:
1. Medical history (especially smoking habits)
2. Physical examination (checking pulses, skin changes)
3. Blood tests (to rule out diabetes or autoimmune diseases)
4. Imaging tests (angiography, Doppler ultrasound)
5. Biopsy (rarely needed)

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Early diagnosis is key to preventing severe complications like amputations.

How Can Buerger’s Disease Be Managed?

There is no cure for Buerger’s Disease, but the most effective treatment is quitting tobacco completely. Other management strategies include:

1. Quit Smoking (The Most Critical Step)

  • Nicotine replacement therapy (patches, gums)
  • Counseling or support groups
  • Prescription medications (like bupropion or varenicline)

Even one cigarette can worsen symptoms, so complete cessation is necessary.

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2. Medications

  • Vasodilators (to improve blood flow)
  • Pain relievers (for severe discomfort)
  • Antibiotics (if infections develop in ulcers)

3. Lifestyle Changes

  • Avoid cold temperatures (can worsen symptoms)
  • Exercise carefully (gentle walking to improve circulation)
  • Proper foot care (keep feet clean, avoid injuries)
  • Healthy diet (to support overall vascular health)

4. Surgical Options (In Severe Cases)

  • Sympathectomy (nerve surgery to improve blood flow)
  • Amputation (only if gangrene develops)

When Should You See a Doctor?

If you experience:

  • ✔ Persistent pain or numbness in hands/feet
  • ✔ Slow-healing sores or ulcers
  • ✔ Cold, discolored fingers/toes

Consult a vascular specialist immediately. Early intervention can prevent complications.

Can Buerger’s Disease Be Prevented?

The only proven prevention method is avoiding tobacco. If you smoke, quitting now significantly reduces your risk.

Final Thoughts

Buerger’s Disease is a serious but preventable condition. The most important step is quitting smoking—this alone can halt disease progression and improve quality of life. If you or a loved one shows symptoms, seek medical advice promptly.

Need help quitting smoking or managing vascular health?

Consult an expert at Apollo 24|7 for personalized guidance. Book an appointment today for a healthier tomorrow.

Consult Top General Practitioner

Dr. Anamika Krishnan, General Practitioner

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