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Liver Cancer Medications and Treatment Options

know about liver cancer, medications, treatment, different types of therapies and management of possible side effects. Learn about lifestyle tips to manage liver cancer and more.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. Siri Nallapu MBBS

Last updated on 8th Aug, 2025

Introduction 

Facing a liver cancer diagnosis can be overwhelming, but understanding your treatment options can help you make informed decisions about your care. The symptoms in early sage are rare, later symptoms like body weight loss, stomach ache and vomiting can appear. 

This guide explains the different medications and treatments available for liver cancer in simple, easy-to-understand terms.

Understanding Liver Cancer

Liver cancer occurs when abnormal cells grow uncontrollably in the liver. It can be primary (starting in the liver) or secondary (spreading from other organs). The most common type is hepatocellular carcinoma (HCC).

Consult Top Specialists for Personalised Tips

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Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

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Symptoms of Liver Cancer

Early stages may not show symptoms, but as cancer progresses, you may experience:

  •  Unexplained weight loss

  •  Loss of appetite

  •  Nausea or vomiting

  •  Pain or swelling in the abdomen

  •  Jaundice (yellowing of skin and eyes)

  •  Fatigue

If you notice these symptoms, consult a doctor for proper diagnosis.

Treatment Options for Liver Cancer

Treatment depends on the stage of cancer, liver function, and overall health. Here are the main options:

1. Surgery

  • Partial Hepatectomy – Removal of the tumor and a portion of the liver (if the liver is healthy enough).

  • Liver Transplant – Replacing the diseased liver with a healthy donor liver (suitable for early-stage cancer).

2. Localized Treatments (Non-Surgical)

These target cancer cells without removing them surgically:

  •  Radiofrequency Ablation (RFA) – Uses heat to destroy cancer cells.

  •  Microwave Ablation – Similar to RFA but uses microwaves.

  •  Cryoablation – Freezes cancer cells.

  •  Ethanol (Alcohol) Injection – Injects alcohol directly into the tumor to kill cancer cells.

  •  Transarterial Chemoembolization (TACE) – Delivers chemotherapy directly to the liver while blocking blood supply to the tumor.

3. Radiation Therapy

Uses high-energy rays to kill cancer cells. Stereotactic body radiotherapy (SBRT) is a precise form used for liver cancer.

4. Targeted Therapy

These drugs attack specific weaknesses in cancer cells:

  • Sorafenib (Nexavar) – Slows tumor growth by blocking blood supply.

  • Lenvatinib (Lenvima) – Works similarly to Sorafenib. Regorafenib (Stivarga) – Used if Sorafenib stops working.

  • Cabozantinib (Cabometyx) – Helps in advanced liver cancer.

5. Immunotherapy

Boosts the immune system to fight cancer:

  •  Nivolumab (Opdivo)

  •  Pembrolizumab (Keytruda)

  •  Atezolizumab (Tecentriq) + Bevacizumab (Avastin) – A combination therapy for advanced liver cancer.

6. Chemotherapy

Less commonly used for liver cancer but may be an option if other treatments fail.

Managing Side Effects of Treatment

Different treatments can cause side effects, such as:

  • Fatigue

  • Nausea

  • Skin rashes (from targeted therapy)

  • Diarrhea

  • Loss of appetite

Tips to Manage Side Effects:

  •  Eat small, frequent meals.

  •  Stay hydrated.

  •  Rest when needed.

  •  Use prescribed medications to control nausea or pain.

Lifestyle and Dietary Tips for Liver Cancer Patients

A healthy lifestyle can support treatment and recovery:

  • Eat a balanced diet (lean proteins, whole grains, fruits, and vegetables).

  • Limit alcohol (as it damages the liver).

  • Avoid processed foods and excess salt.

  • Exercise gently (walking, yoga) to maintain strength.

  • Get vaccinated for hepatitis B if not already protected.

When to Seek Help?

If you experience:

  • Severe pain

  • Persistent vomiting

  • High fever

  • Worsening jaundice

  • Contact your doctor immediately.

Final Thoughts

Liver cancer treatment has advanced significantly, offering hope for many patients. Early detection and the right treatment plan can improve outcomes. Stay informed, follow medical advice, and maintain a positive outlook as only your health journey matters.

Consult Top Specialists

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

135 Cashback

900

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

89%

(25+ Patients)

1000

100 Cashback

2000

No Booking Fees

Consult Top Specialists for Personalised Tips

Dr.sanchayan Mandal, Oncologist

Dr.sanchayan Mandal

Oncologist

17 Years • MBBS, DrNB( MEDICAL ONCOLOGY), DNB (RADIOTHERAPY),ECMO. PDCR. ASCO

Kolkata

Dr. Sanchayan Mandal Oncology Clinic, Kolkata

1500

1500

No Booking Fees

Dr. Sanchayan Mandal, Oncologist

Dr. Sanchayan Mandal

Oncologist

17 Years • MBBS, DNB Raditherapy, DrNB Medical Oncology

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

1500

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

135 Cashback

900

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

89%

(25+ Patients)

1000

100 Cashback

2000

No Booking Fees

Consult Top Specialists

Dr.sanchayan Mandal, Oncologist

Dr.sanchayan Mandal

Oncologist

17 Years • MBBS, DrNB( MEDICAL ONCOLOGY), DNB (RADIOTHERAPY),ECMO. PDCR. ASCO

Kolkata

Dr. Sanchayan Mandal Oncology Clinic, Kolkata

1500

1500

No Booking Fees

Dr. Sanchayan Mandal, Oncologist

Dr. Sanchayan Mandal

Oncologist

17 Years • MBBS, DNB Raditherapy, DrNB Medical Oncology

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

1500

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

135 Cashback

900

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

89%

(25+ Patients)

1000

100 Cashback

2000

No Booking Fees

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