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Liver Cancer Medications and Treatment Options

know about liver cancer, medications, treatment, different types of therapies and management of possible side effects. Learn about lifestyle tips to manage liver cancer and more.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. Siri Nallapu MBBS

Last updated on 8th Aug, 2025

Introduction 

Facing a liver cancer diagnosis can be overwhelming, but understanding your treatment options can help you make informed decisions about your care. The symptoms in early sage are rare, later symptoms like body weight loss, stomach ache and vomiting can appear. 

This guide explains the different medications and treatments available for liver cancer in simple, easy-to-understand terms.

Understanding Liver Cancer

Liver cancer occurs when abnormal cells grow uncontrollably in the liver. It can be primary (starting in the liver) or secondary (spreading from other organs). The most common type is hepatocellular carcinoma (HCC).

Consult Top Specialists for Personalised Tips

Dr. Harsh J Shah, Surgical Oncologist

Dr. Harsh J Shah

Surgical Oncologist

15 Years • MS, MCh (GI), DrNB (GI)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

1500

1300

No Booking Fees

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

97%

(50+ Patients)

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

Dr. Vishal Choksi, Head and Neck Surgical Oncologist

Dr. Vishal Choksi

Head and Neck Surgical Oncologist

20 Years • American Head & Neck Society (AHNS) certified from Memorial Sloan-Kettering Cancer Centre, American Board of Surgery (ABS) certified general surgeon, MBBS (India)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

4000

3000

No Booking Fees

Dr. Praveen Kumar Garg, Surgical Oncologist

Dr. Praveen Kumar Garg

Surgical Oncologist

26 Years • MBBS, M.S.(Gen.Surg.), M.Ch.(OncoSurg.)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

94%

(50+ Patients)

1000

2000

No Booking Fees

Symptoms of Liver Cancer

Early stages may not show symptoms, but as cancer progresses, you may experience:

  •  Unexplained weight loss

  •  Loss of appetite

  •  Nausea or vomiting

  •  Pain or swelling in the abdomen

  •  Jaundice (yellowing of skin and eyes)

  •  Fatigue

If you notice these symptoms, consult a doctor for proper diagnosis.

Treatment Options for Liver Cancer

Treatment depends on the stage of cancer, liver function, and overall health. Here are the main options:

1. Surgery

  • Partial Hepatectomy – Removal of the tumor and a portion of the liver (if the liver is healthy enough).

  • Liver Transplant – Replacing the diseased liver with a healthy donor liver (suitable for early-stage cancer).

2. Localized Treatments (Non-Surgical)

These target cancer cells without removing them surgically:

  •  Radiofrequency Ablation (RFA) – Uses heat to destroy cancer cells.

  •  Microwave Ablation – Similar to RFA but uses microwaves.

  •  Cryoablation – Freezes cancer cells.

  •  Ethanol (Alcohol) Injection – Injects alcohol directly into the tumor to kill cancer cells.

  •  Transarterial Chemoembolization (TACE) – Delivers chemotherapy directly to the liver while blocking blood supply to the tumor.

3. Radiation Therapy

Uses high-energy rays to kill cancer cells. Stereotactic body radiotherapy (SBRT) is a precise form used for liver cancer.

4. Targeted Therapy

These drugs attack specific weaknesses in cancer cells:

  • Sorafenib (Nexavar) – Slows tumor growth by blocking blood supply.

  • Lenvatinib (Lenvima) – Works similarly to Sorafenib. Regorafenib (Stivarga) – Used if Sorafenib stops working.

  • Cabozantinib (Cabometyx) – Helps in advanced liver cancer.

5. Immunotherapy

Boosts the immune system to fight cancer:

  •  Nivolumab (Opdivo)

  •  Pembrolizumab (Keytruda)

  •  Atezolizumab (Tecentriq) + Bevacizumab (Avastin) – A combination therapy for advanced liver cancer.

6. Chemotherapy

Less commonly used for liver cancer but may be an option if other treatments fail.

Managing Side Effects of Treatment

Different treatments can cause side effects, such as:

  • Fatigue

  • Nausea

  • Skin rashes (from targeted therapy)

  • Diarrhea

  • Loss of appetite

Tips to Manage Side Effects:

  •  Eat small, frequent meals.

  •  Stay hydrated.

  •  Rest when needed.

  •  Use prescribed medications to control nausea or pain.

Lifestyle and Dietary Tips for Liver Cancer Patients

A healthy lifestyle can support treatment and recovery:

  • Eat a balanced diet (lean proteins, whole grains, fruits, and vegetables).

  • Limit alcohol (as it damages the liver).

  • Avoid processed foods and excess salt.

  • Exercise gently (walking, yoga) to maintain strength.

  • Get vaccinated for hepatitis B if not already protected.

When to Seek Help?

If you experience:

  • Severe pain

  • Persistent vomiting

  • High fever

  • Worsening jaundice

  • Contact your doctor immediately.

Final Thoughts

Liver cancer treatment has advanced significantly, offering hope for many patients. Early detection and the right treatment plan can improve outcomes. Stay informed, follow medical advice, and maintain a positive outlook as only your health journey matters.

Consult Top Specialists

Dr. Harsh J Shah, Surgical Oncologist

Dr. Harsh J Shah

Surgical Oncologist

15 Years • MS, MCh (GI), DrNB (GI)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

1500

1300

No Booking Fees

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

97%

(50+ Patients)

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

Dr. Vishal Choksi, Head and Neck Surgical Oncologist

Dr. Vishal Choksi

Head and Neck Surgical Oncologist

20 Years • American Head & Neck Society (AHNS) certified from Memorial Sloan-Kettering Cancer Centre, American Board of Surgery (ABS) certified general surgeon, MBBS (India)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

4000

3000

No Booking Fees

Dr. Praveen Kumar Garg, Surgical Oncologist

Dr. Praveen Kumar Garg

Surgical Oncologist

26 Years • MBBS, M.S.(Gen.Surg.), M.Ch.(OncoSurg.)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

94%

(50+ Patients)

1000

2000

No Booking Fees

Consult Top Specialists for Personalised Tips

Dr. Harsh J Shah, Surgical Oncologist

Dr. Harsh J Shah

Surgical Oncologist

15 Years • MS, MCh (GI), DrNB (GI)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

1500

1300

No Booking Fees

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

97%

(50+ Patients)

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

Dr. Vishal Choksi, Head and Neck Surgical Oncologist

Dr. Vishal Choksi

Head and Neck Surgical Oncologist

20 Years • American Head & Neck Society (AHNS) certified from Memorial Sloan-Kettering Cancer Centre, American Board of Surgery (ABS) certified general surgeon, MBBS (India)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

4000

3000

No Booking Fees

Dr. Praveen Kumar Garg, Surgical Oncologist

Dr. Praveen Kumar Garg

Surgical Oncologist

26 Years • MBBS, M.S.(Gen.Surg.), M.Ch.(OncoSurg.)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

94%

(50+ Patients)

1000

2000

No Booking Fees

Consult Top Specialists

Dr. Harsh J Shah, Surgical Oncologist

Dr. Harsh J Shah

Surgical Oncologist

15 Years • MS, MCh (GI), DrNB (GI)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

1500

1300

No Booking Fees

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

97%

(50+ Patients)

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

Dr. Vishal Choksi, Head and Neck Surgical Oncologist

Dr. Vishal Choksi

Head and Neck Surgical Oncologist

20 Years • American Head & Neck Society (AHNS) certified from Memorial Sloan-Kettering Cancer Centre, American Board of Surgery (ABS) certified general surgeon, MBBS (India)

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

4000

3000

No Booking Fees

Dr. Praveen Kumar Garg, Surgical Oncologist

Dr. Praveen Kumar Garg

Surgical Oncologist

26 Years • MBBS, M.S.(Gen.Surg.), M.Ch.(OncoSurg.)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

94%

(50+ Patients)

1000

2000

No Booking Fees

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