Understanding Emphysema
Know about the emphysema, what it is, emphysema versus copd, recognise signs and symptoms, causes, treatment options, lifestyle management and prevention of emphysema and more.


Introduction
Do you find yourself increasingly short of breath after activities that used to be easy, like climbing a flight of stairs or walking the dog? This persistent breathlessness, often accompanied by a lingering cough, could be a sign of emphysema, a serious and progressive lung disease. Emphysema is a major component of Chronic Obstructive Pulmonary Disease (COPD), a condition that affects millions worldwide by slowly damaging the air sacs in the lungs, making it increasingly difficult to breathe. This comprehensive guide will help you understand what emphysema is, what causes it, and how to recognize its symptoms.
What is Emphysema? The Basics of This Lung Condition
Emphysema is a chronic lung disease characterised by the gradual destruction of the alveoli, the tiny, grape-like air sacs located at the end of the bronchial tubes deep within your lungs. These sacs are responsible for a critical function: the exchange of oxygen and carbon dioxide between the air you breathe and your blood. In a healthy lung, the alveoli are elastic and springy, expanding and contracting with each breath.
In a person with emphysema, the walls of these air sacs are damaged and lose their elasticity. They eventually rupture, creating fewer, larger air spaces instead of many small, efficient ones. This drastically reduces the surface area available for gas exchange, trapping stale air in the lungs and making it hard to expel carbon dioxide and draw in fresh oxygen. The lungs slowly over-inflate, leading to the characteristic shortness of breath.
Consult a Pulmonologist for Personalised Advice
Emphysema vs. COPD: What's the Connection?
It's common to see the terms emphysema and COPD used interchangeably, but there's a key distinction. Think of COPD as an umbrella term for a group of lung diseases that cause airflow blockage and breathing-related problems. The two most common conditions under this umbrella are emphysema and chronic bronchitis.
Many people with COPD have a combination of both. Emphysema specifically involves damage to the alveoli, while chronic bronchitis is defined by a long-term cough with mucus due to inflammation of the bronchial tubes. The shared result is difficulty moving air in and out of the lungs.
How Emphysema Damages Your Lungs: The Role of the Alveoli
The damage to the alveoli is primarily caused by an imbalance in the lung's natural repair processes. Normally, the lungs are protected by enzymes and proteins. Long-term exposure to irritants like cigarette smoke triggers chronic inflammation and an overproduction of enzymes that break down the elastic fibres in the alveolar walls. Over time, this relentless process causes the sacs to lose their shape and collapse during exhalation, trapping air. This trapped air is why individuals with advanced emphysema often have a "barrel-chested" appearance.
Recognising the Signs: Common Emphysema Symptoms
The symptoms of emphysema often develop slowly and may go unnoticed until significant lung damage has already occurred. The most prevalent symptom, and usually the first one people notice, is shortness of breath (medically known as dyspnea). Initially, this may only occur during physical activity, but as the disease progresses, it can happen even while at rest.
Early Warning Signs You Shouldn't Ignore
Beyond breathlessness, early signs can be subtle and easily attributed to other factors like aging or being out of shape. These include:
- A persistent cough, often referred to as a "smoker's cough."
- Wheezing or a whistling sound when you breathe.
- A feeling of tightness in the chest.
- Producing excess mucus or phlegm.
- Reduced stamina and increased fatigue during daily activities.
If you experience these symptoms persistently, especially if you have a history of smoking, it is crucial to seek medical
evaluation. If these symptoms persist beyond two weeks, consult a doctor online with Apollo24|7 for further evaluation.
How do Symptoms Progress Over Time?
As emphysema advances, symptoms become more severe and debilitating. Later-stage signs may include:
- Frequent respiratory infections like colds and flu.
- Significant weight loss and loss of appetite.
- Swelling in the ankles, feet, or legs due to cor pulmonale (a heart condition caused by lung disease).
- Difficulty sleeping or breathing while lying flat, requiring extra pillows.
- A bluish tint to the lips or fingernail beds (cyanosis) due to low oxygen levels.
What Causes Emphysema? The Primary Risk Factors
While several factors can contribute, one overwhelming cause is responsible for the vast majority of emphysema cases.
The Irrefutable Link Between Smoking and Emphysema
Cigarette smoking is the number one risk factor for developing emphysema. It's estimated that smoking is responsible for up to 90% of COPD-related deaths. The harmful chemicals in tobacco smoke irritate the airways, destroy the elastic fibers in the lungs, trigger inflammation, and disable the lungs' natural defense systems. The risk increases with the number of years smoked and the number of packs smoked per day. However, it's never too late to quit. Quitting smoking is the single most effective action to slow the progression of the disease.
Beyond Smoking: Other Causes and Risk Factors
Non-smokers can also develop emphysema due to other factors.
Alpha-1 Antitrypsin Deficiency: The Genetic Factor
A small percentage of people develop emphysema due to a hereditary disorder called Alpha-1 Antitrypsin Deficiency.
Alpha-1 antitrypsin is a protein that protects the lungs. A deficiency in this protein makes the lungs susceptible to damage from environmental irritants and even normal aging processes, often leading to emphysema at a much younger age (30s or 40s).
Long-Term Exposure to Air Pollutants and Irritants
Prolonged exposure to secondhand smoke, occupational dust and chemicals (e.g., from coal, grain, wood, textiles), and
both indoor and outdoor air pollution (e.g., biomass fuels used for cooking and heating in poorly ventilated homes) are significant risk factors for the progression of emphysema.
Getting a Diagnosis: How Doctors Identify Emphysema
Diagnosing emphysema involves a review of your symptoms, medical history, and a physical exam, followed by definitive tests to assess lung function.
Key Diagnostic Tests: From Spirometry to CT Scans
The most common and critical test is spirometry, a type of pulmonary function test. You will be asked to blow into a
tube connected to a machine (a spirometer) as hard and as fast as you can. This measures how much air you can exhale and how quickly you can do it, helping to identify airflow obstruction.
Other diagnostic tools include:
- Imaging Tests: Chest X-rays can show over-inflated lungs and other emphysema-related changes. CT scans provide a more detailed view and can detect emphysema earlier and more precisely.
- Blood Tests: An arterial blood gas test measures how well your lungs are transferring oxygen to your blood and
removing carbon dioxide. A blood test can also check for Alpha-1 Antitrypsin Deficiency.
Apollo24|7 offers convenient home collection for tests like vitamin D or HbA1c, though specific lung function tests
require clinical visits.
The Importance of Early Diagnosis and Intervention
Early diagnosis is paramount. While the lung damage from emphysema is not reversible, early intervention can
drastically slow the disease's progression, relieve symptoms, improve your ability to stay active, and prevent serious complications. It provides the motivation and medical support needed to make crucial lifestyle changes, primarily quitting smoking.
Emphysema Treatment Options: Managing the Disease
There is no cure for emphysema, but a variety of emphysema treatment options can help manage symptoms, improve quality of life, and reduce the frequency and severity of flare-ups (exacerbations).
Medications: Bronchodilators, Inhaled Steroids, and More
- Bronchodilators: These are the cornerstone of medication therapy. Inhaled through an inhaler or nebulizer, they work
by relaxing the muscles around the airways, helping to open them and make breathing easier. They are often prescribed
for daily use (long-acting) and for quick relief during breathlessness (short-acting). - Inhaled Corticosteroids: These drugs reduce inflammation in the airways and are often combined with long-acting
bronchodilators for people with frequent flare-ups. - Other Medications: may include phosphodiesterase-4 inhibitors (for severe COPD), theophylline (an older oral
medication), or antibiotics to treat respiratory infections.
Pulmonary Rehabilitation: Strengthening Your Lungs and Body
This is a personalised program that combines exercise training, nutritional advice, and education. A key component is
teaching breathing techniques, like pursed-lip breathing, which helps empty trapped air from the lungs. Exercise training strengthens the muscles you use for breathing and improves your overall endurance, making daily tasks less exhausting.
Oxygen Therapy: When and Why It's Needed
For those with advanced emphysema and low blood oxygen levels, supplemental oxygen therapy can be life-changing. Using an oxygen concentrator or tank for several hours a day or during activity can reduce shortness of breath, protect the heart and other organs from damage, improve sleep, and increase survival.
Surgical Options for Severe Emphysema
In select cases where medications are not enough, surgery may be an option. Procedures include lung volume reduction surgery (removing damaged portions of the lung to help the remaining healthy tissue work better) or, in very severe cases, a lung transplant.
Living with Emphysema: Daily Management and Lifestyle Changes
A proactive approach to daily life is essential for managing emphysema effectively.
Lifestyle Modifications for Better Lung Health
- Quit Smoking: This is non-negotiable. It is the most important step you can take.
- Avoid Lung Irritants: Stay indoors on days with high air pollution, avoid secondhand smoke, and wear a mask if
exposed to dust or chemicals. - Get Vaccinated: Respiratory infections can be very dangerous. Annual flu shots and pneumococcal vaccines are crucial.
Eat a Healthy Diet: A balanced diet helps maintain energy levels and strength. Some people with advanced emphysema need to focus on maintaining a healthy weight. - Stay Active: Regular, gentle exercise as tolerated helps improve cardiovascular fitness and muscle strength.
Preventing Infections and Managing Flare-Ups
Be vigilant about handwashing and avoid close contact with people who are sick. Recognise the signs of a flare-up
(increased shortness of breath, change in mucus colour or amount) and have an action plan from your doctor on what to do, which may include starting a course of antibiotics or steroids. If your condition does not improve after trying these methods, book a physical visit to a doctor with Apollo24|7 to adjust your treatment plan.
Conclusion
Understanding emphysema is the first powerful step toward taking control of your respiratory health. While it is a serious and chronic condition, it is also highly manageable. The journey involves a combination of modern medical treatments, crucial lifestyle adjustments, and a strong partnership with your healthcare team. By adhering to your prescribed treatment plan, engaging in pulmonary rehabilitation, and staying vigilant about your health, you can significantly slow the progression of emphysema, reduce uncomfortable symptoms, and maintain an active and fulfilling life for years to come.
Consult a Pulmonologist for Personalised Advice
Consult a Pulmonologist for Personalised Advice

Dr Vishwa Vijeth K.
Pulmonology Respiratory Medicine Specialist
8 Years • MBBS, MD ( Respiratory Medicine)
Bangalore
Apollo Clinic Bellandur, Bangalore

Dr Rakesh Bilagi
Pulmonology Respiratory Medicine Specialist
10 Years • MBBS MD PULMONOLOGIST
Bengaluru
Apollo Clinic, JP nagar, Bengaluru

Dr. Preeti Kathail
General Physician/ Internal Medicine Specialist
17 Years • MBBS, PGDHHM
Bangalore
Apollo Clinic Bellandur, Bangalore
(25+ Patients)
Dr. Varun Rajpal
Pulmonology Respiratory Medicine Specialist
12 Years • MBBS, DNB Respiratory Medicine, EDARM, IDCCM,FCCS,FSM, Certificate course in Diabetes.
Noida
DR. VARUN RAJPAL Lungs And Respiratory Care clinic., Noida
Dr. Naseeha Mohammed S V
Pulmonology Respiratory Medicine Specialist
6 Years • MBBS, MD ,DNB Respiratory Medicine
Bengaluru
Apollo Clinic, Sarjapur Road, Bengaluru
Consult a Pulmonologist for Personalised Advice

Dr Vishwa Vijeth K.
Pulmonology Respiratory Medicine Specialist
8 Years • MBBS, MD ( Respiratory Medicine)
Bangalore
Apollo Clinic Bellandur, Bangalore

Dr Rakesh Bilagi
Pulmonology Respiratory Medicine Specialist
10 Years • MBBS MD PULMONOLOGIST
Bengaluru
Apollo Clinic, JP nagar, Bengaluru

Dr. Preeti Kathail
General Physician/ Internal Medicine Specialist
17 Years • MBBS, PGDHHM
Bangalore
Apollo Clinic Bellandur, Bangalore
(25+ Patients)
Dr. Varun Rajpal
Pulmonology Respiratory Medicine Specialist
12 Years • MBBS, DNB Respiratory Medicine, EDARM, IDCCM,FCCS,FSM, Certificate course in Diabetes.
Noida
DR. VARUN RAJPAL Lungs And Respiratory Care clinic., Noida
Dr. Naseeha Mohammed S V
Pulmonology Respiratory Medicine Specialist
6 Years • MBBS, MD ,DNB Respiratory Medicine
Bengaluru
Apollo Clinic, Sarjapur Road, Bengaluru