Metropolis Pregascreen Reflex Testing Overview
Know about the metropolis pregscreen reflex testing, what it tests, how its done, test result analysis and more.
Written by Dr. M L Ezhilarasan
Reviewed by Dr. Rohinipriyanka Pondugula MBBS
Last updated on 28th Aug, 2025
Introduction
Pregnancy is an exciting journey with crucial responsibilities and keeping up with birth priorities. Ensuring both you and your baby stay healthy is the priority. One important test you may come across is the Metropolis Pregascreen Reflex Testing during this phase. If you're wondering what this test is, why it’s needed, and how it helps, this article will guide you through everything in simple terms.
What is Pregascreen Reflex Testing?
The Pregascreen Reflex Testing is a specialised blood test designed to assess the risk of certain genetic and
chromosomal abnormalities in your developing baby. It is a non-invasive prenatal screening (NIPS) test that analyses small fragments of the baby’s DNA present in the mother’s bloodstream.
This test helps detect conditions like:
- Down syndrome (Trisomy 21)
- Edwards syndrome (Trisomy 18)
- Patau syndrome (Trisomy 13)
- Sex chromosome abnormalities
Unlike invasive tests (like amniocentesis), Pregascreen is safe, painless, and carries no risk to the baby.
Consult a Gynaecologist for Personalised Advice
Who Should Consider This Test?
Pregascreen Reflex Testing is recommended for:
- Women aged 35 or older (higher risk of chromosomal abnormalities).
- Those with a family history of genetic disorders.
- If previous screenings (like ultrasound or double marker test) show abnormal results.
- Couples who want early and accurate screening without invasive procedures.
However, even if you don’t fall into these categories, you can still opt for this test for peace of mind.
How is the Test Done?
The process is simple:
- A small blood sample is taken from your arm (just like a regular blood test).
- The sample is sent to a lab where advanced technology analyses the baby’s DNA.
- Results are usually available in 7-10 days.
No fasting or special preparation is needed.
Understanding Your Test Results
Your report will indicate whether the risk for certain conditions is low or high.
- Low risk means it’s very unlikely your baby has the conditions tested.
- High risk means further diagnostic tests (like amniocentesis) may be needed for confirmation.
Remember, Pregascreen is a screening test, not a diagnostic one. A high-risk result doesn’t always mean your baby has
the condition—it just means more tests are needed.
Why Choose Pregascreen Over Other Tests?
- Highly Accurate – Detects over 99% of Down syndrome cases.
- Safe – No risk of miscarriage (unlike invasive tests).
- Early Detection – Can be done as early as 10 weeks into pregnancy.
- Quick & Convenient – Just a blood draw, no hospitalisation required.
Tips for a Healthy Pregnancy
While tests like Pregascreen help monitor your baby’s health, here are some ways to support a healthy pregnancy
- Eat a balanced diet – Include fruits, vegetables, whole grains, and proteins.
- Stay hydrated – Drink plenty of water.
- Take prenatal vitamins – Especially folic acid, iron, and calcium.
- Exercise gently – Walking, yoga, or swimming can help.
- Avoid stress – Practice relaxation techniques like deep breathing.
- Get regular check-ups – Follow your doctor’s advice for ultrasounds and tests.
When to Consult a Doctor?
If your Pregascreen results show a high-risk indication, your doctor may recommend further testing. Always discuss
your reports with a genetic counsellor or obstetrician to understand the next steps.
Final Thoughts
Pregnancy is a beautiful phase, and staying informed helps you make the best decisions for your baby’s health. The Metropolis Pregascreen Reflex Testing is a reliable, safe, and effective way to screen for genetic conditions early in pregnancy.
Consult a Gynaecologist for Personalised Advice
Consult a Gynaecologist for Personalised Advice
Dr Bhawna Garg
Gynaecological Oncologist
26 Years • MBBS, MS, (PGI MS ROHTAK) FELLOWSHIP GYNECOLOGY ONCOLOGY, (CANCER INSTITUTE CHENNAI)
Delhi
Apollo Hospitals Indraprastha, Delhi
Dr. Rupam Manna
Radiation Specialist Oncologist
4 Years • MBBS MD(RADIO THERAPY)
Barasat
Diab-Eat-Ease, Barasat
Dr. Sreeparna Roy
Obstetrician and Gynaecologist
8 Years • MBBS , MS (OBSTETRICS & GYNAECOLOGY), Fellowship in Infertility, Endoscopy & Ultrasonography), Fellowship in Laparoscopy & Hysteroscopy,DRM
Kolkata
Dr Utsa Basu Clinic, Kolkata
Dr. Renuka Chandran
Obstetrician and Gynaecologist
30 Years • MBBS, MD, DGO, Masters in Advanced Ultrasound in Obs & Gynea
Bangalore
Apollo Clinic Bellandur, Bangalore
Dr. Sandeep Muzumder
Radiation Specialist Oncologist
21 Years • MBBS (JIPMER, Pondicherry), MD (AIIMS, New Delhi)
Bhubaneswar
Apollo Hospitals Old Sainik School Road, Bhubaneswar
Consult a Gynaecologist for Personalised Advice
Dr Bhawna Garg
Gynaecological Oncologist
26 Years • MBBS, MS, (PGI MS ROHTAK) FELLOWSHIP GYNECOLOGY ONCOLOGY, (CANCER INSTITUTE CHENNAI)
Delhi
Apollo Hospitals Indraprastha, Delhi
Dr. Rupam Manna
Radiation Specialist Oncologist
4 Years • MBBS MD(RADIO THERAPY)
Barasat
Diab-Eat-Ease, Barasat
Dr. Sreeparna Roy
Obstetrician and Gynaecologist
8 Years • MBBS , MS (OBSTETRICS & GYNAECOLOGY), Fellowship in Infertility, Endoscopy & Ultrasonography), Fellowship in Laparoscopy & Hysteroscopy,DRM
Kolkata
Dr Utsa Basu Clinic, Kolkata
Dr. Renuka Chandran
Obstetrician and Gynaecologist
30 Years • MBBS, MD, DGO, Masters in Advanced Ultrasound in Obs & Gynea
Bangalore
Apollo Clinic Bellandur, Bangalore
Dr. Sandeep Muzumder
Radiation Specialist Oncologist
21 Years • MBBS (JIPMER, Pondicherry), MD (AIIMS, New Delhi)
Bhubaneswar
Apollo Hospitals Old Sainik School Road, Bhubaneswar
