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Understanding Drug-Induced Parkinsonism

Understand Drug-Induced Parkinsonism, a condition that mimics Parkinson’s disease symptoms due to certain medications. Learn about its causes, symptoms, diagnosis, and treatment options for better management.

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Written by Dr. J T Hema Pratima

Reviewed by Dr. Md Yusuf Shareef MBBS

Last updated on 25th Aug, 2025

Parkinsonism is a condition that affects movement, causing symptoms like tremors, stiffness, and slow movements. While Parkinson’s disease is the most well-known cause, certain medications can also trigger similar symptoms, this is called drug-induced parkinsonism (DIP). If you or a loved one is experiencing these symptoms after starting a new medication, it’s important to understand what’s happening and how to manage it.

What is Drug-Induced Parkinsonism?

Drug-induced parkinsonism occurs when certain medications interfere with dopamine, a chemical in the brain that helps control movement. When dopamine levels drop, movement-related symptoms similar to Parkinson’s disease can appear. The good news is that DIP is often reversible once the offending medication is stopped or adjusted.

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Common Symptoms

The symptoms of DIP can develop gradually or suddenly and may include:

  • Tremors (shaking, usually in the hands)

  • Stiffness in muscles, making movement difficult

  • Slowed movements (bradykinesia), such as walking slowly or trouble getting up from a chair

  • Balance problems, increasing the risk of falls

  • Loss of facial expression, making a person appear emotionless

These symptoms can be distressing, but recognizing them early can help in getting the right treatment.

Which Medications Can Cause It?

Several types of medications can lead to DIP, including:

1. Antipsychotics (used for mental health conditions like schizophrenia or bipolar disorder)

  • Examples: Haloperidol, Risperidone

2. Anti-nausea drugs

  • Examples: Metoclopramide, Prochlorperazine

3. Some antidepressants

  • Example: Fluoxetine (in rare cases)

4. Blood pressure medications

  • Example: Reserpine

5. Anti-epileptic drugs

  • Example: Valproate

If you’re taking any of these and notice movement-related symptoms, consult your doctor and don’t stop the medication on your own.

How is DIP Diagnosed?

Your doctor will review your medical history, current medications, and symptoms. They may also perform a neurological exam to check for movement problems. In some cases, imaging tests like an MRI may be done to rule out other conditions.

How is it Treated?

The most effective treatment is stopping or changing the medication causing the symptoms. However, this should always be done under medical supervision. Sometimes, symptoms improve within weeks, but in some cases, it may take months.

If stopping the medication isn’t possible, your doctor may prescribe:

  • Dopamine-enhancing drugs (like Levodopa, though they don’t always work for DIP)

  • Physical therapy to improve mobility and reduce stiffness

Lifestyle Tips to Manage Symptoms

While medical treatment is essential, these lifestyle changes can help:

1. Stay Active – Gentle exercises like walking, yoga, or stretching can improve flexibility and balance.

2. Eat a Balanced Diet – Foods rich in antioxidants (berries, leafy greens) and omega-3 (fish, nuts) support brain health.

3. Fall Prevention – Use handrails, wear non-slip footwear, and keep walkways clear to avoid falls.

4. Stay Hydrated – Dehydration can worsen stiffness and fatigue.

5. Mental Health Support – DIP can be frustrating; counseling or support groups may help.

When to See a Doctor

If you notice any movement-related symptoms after starting a new medication, consult your doctor immediately. Early intervention can prevent worsening symptoms.

If you need expert advice, you can book a consultation with a neurologist through Apollo 24|7 for personalized care.

Conclusion

Drug-induced parkinsonism can be alarming, but it’s often treatable. Recognizing the symptoms early and working with your doctor can lead to a full recovery. Never stop a medication without medical guidance, and remember, help is available.

Consult top Neurologist

Dr. Avinash Gupta, Neurologist

Dr. Avinash Gupta

Neurologist

12 Years • MBBS, DNB - Neurology

Bilaspur

Apollo Hospitals Seepat Road, Bilaspur

recommendation

82%

(125+ Patients)

800

80 Cashback

800

No Booking Fees

Dr. Amit Kapoor, Neurosurgeon

Dr. Amit Kapoor

Neurosurgeon

18 Years • D.N.B NeuroSurg.

Delhi

Apollo Hospitals Indraprastha, Delhi

1500

150 Cashback

Consult top Neurologist

Dr. Avinash Gupta, Neurologist

Dr. Avinash Gupta

Neurologist

12 Years • MBBS, DNB - Neurology

Bilaspur

Apollo Hospitals Seepat Road, Bilaspur

recommendation

82%

(125+ Patients)

800

80 Cashback

800

No Booking Fees

Dr Debnath Dwaipayan, Neurosurgeon

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Neurosurgeon

9 Years • MBBS, MS(Gen. Surgery), DrNB (Neurosurgery)

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Apollo Hospitals Indraprastha, Delhi

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150 Cashback

Dr. Amit Kapoor, Neurosurgeon

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Neurosurgeon

18 Years • D.N.B NeuroSurg.

Delhi

Apollo Hospitals Indraprastha, Delhi

1500

150 Cashback

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