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Hyperparathyroidism Overview and Treatment Options

Hyperparathyroidism causes high calcium levels and can harm bones, kidneys, and overall health. Learn about its types, symptoms, causes, diagnosis, and effective treatment options including surgery, medication, and lifestyle changes.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. Md Yusuf Shareef MBBS

Last updated on 26th Aug, 2025

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Hyperparathyroidism is a condition where the parathyroid glands (four tiny glands in your neck) produce too much parathyroid hormone (PTH). This hormone helps regulate calcium levels in your blood and bones. When too much PTH is released, it can lead to high calcium levels (hypercalcemia), which can affect your bones, kidneys, and overall health.

Types of Hyperparathyroidism

1. Primary Hyperparathyroidism: The most common type, caused by a non-cancerous tumor (adenoma) in one or more parathyroid glands.
2. Secondary Hyperparathyroidism: Occurs due to another condition (like kidney disease or vitamin D deficiency) that lowers calcium levels, forcing the parathyroid glands to overwork.
3. Tertiary Hyperparathyroidism: A rare form seen in people with long-term kidney problems, where the glands keep producing excess PTH even after calcium levels normalize.

Symptoms of Hyperparathyroidism

Many people with hyperparathyroidism experience mild or no symptoms, especially in the early stages. However, as calcium levels rise, symptoms may include:

  • Bone and muscle issues: Weak bones (osteoporosis), bone pain, muscle weakness.
  • Kidney problems: Frequent urination, kidney stones, or even kidney damage.
  • Digestive troubles: Nausea, vomiting, constipation, or loss of appetite.
  • Neurological effects: Fatigue, depression, memory problems, or confusion.
  • General discomfort: Excessive thirst, joint pain, and high blood pressure.

If you notice these symptoms, especially if they persist, it’s important to consult a doctor.

Causes and Risk Factors

Primary Hyperparathyroidism Causes:

  • A benign tumor (adenoma) in one or more glands.
  • Enlarged parathyroid glands (hyperplasia).
  • Rarely, parathyroid cancer.

Secondary Hyperparathyroidism Causes:

  • Chronic kidney disease (reduces calcium absorption).
  • Severe vitamin D deficiency (needed for calcium absorption).
  •  
  • Poor calcium intake in the diet.

Risk Factors:

  • Being over 50 years old.
  • Being female (women are more likely to develop it).
  • Having a family history of hyperparathyroidism.
  • Previous radiation exposure to the neck.

Diagnosis and Tests

If your doctor suspects hyperparathyroidism, they may recommend:

1. Blood tests: To check calcium, PTH, vitamin D, and kidney function.
2. Urine tests: To measure calcium excretion.
3. Bone density scan (DEXA): To check for osteoporosis.
4. Imaging tests: Ultrasound, CT, or Sestamibi scan to locate abnormal glands.
Early diagnosis helps prevent complications like bone loss and kidney damage.

Treatment Options

The treatment depends on the type and severity of hyperparathyroidism.

1. Primary Hyperparathyroidism Treatment

Surgery (Parathyroidectomy): The most effective treatment, where the overactive gland(s) are removed. It’s minimally invasive with a quick recovery.

  • Medications: If surgery isn’t an option, drugs like Cinacalcet help control calcium levels.
  • Monitoring: If calcium is only slightly high and symptoms are mild, doctors may recommend regular check-ups without immediate surgery.

2. Secondary Hyperparathyroidism Treatment

  • Vitamin D and calcium supplements: To correct deficiencies.
  • Phosphate binders: If kidney disease is the cause.
  • Medications: Like calcimimetics to lower PTH levels.

Consult Top Specialist

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Indrajit Das, General Physician/ Internal Medicine Specialist

Dr. Indrajit Das

General Physician/ Internal Medicine Specialist

4 Years • "MD (Internal medicine) : Gauhati Medical College and Hospital, Guwahati (2018-2021) MD (Pathology) : Gauhati Medical College and Hospital, Guwahati (2012-2015) MBBS (Bachelor of Medicine, Bachelor of Surgery) : Silchar Medical College, Assam (2003-2008) "

Guwahati

Apollo Excelcare Hospital, Guwahati

700

Dr. Haripriya Jagadeesh, General Physician/ Internal Medicine Specialist

Dr. Haripriya Jagadeesh

General Physician/ Internal Medicine Specialist

24 Years • MBBS, AB (Family Physician)

Chennai

Apollo Hospitals Greams Road, Chennai

1500

1500

3. Lifestyle and Dietary Changes

  • Stay hydrated: Helps prevent kidney stones.
  • Exercise regularly: Strengthens bones and muscles.
  • Limit high-calcium foods (if advised by a doctor).
  • Avoid dehydration: Drink plenty of water.
  • Monitor vitamin D levels: Sun exposure and supplements may help.

When to See a Doctor?

If you experience:

  • Persistent fatigue, bone pain, or muscle weakness.
  • Frequent kidney stones.
  • Unexplained high calcium levels in blood tests.
  • Early treatment can prevent complications like osteoporosis and kidney damage.

How Apollo24|7 Can Help

If you suspect hyperparathyroidism or need expert advice, Apollo24|7 offers:

  • Consultations with endocrinologists: Specialists in hormone-related conditions.
  • Diagnostic tests: Blood tests, imaging, and bone density scans.
  • Personalized treatment plans: Including surgical and non-surgical options.
  • You can easily book a consultation or schedule tests through the Apollo24|7 app or website.

Final Thoughts

Hyperparathyroidism is a manageable condition with the right diagnosis and treatment. If you experience symptoms or have risk factors, don’t hesitate to seek medical advice. Early intervention can help you maintain strong bones, healthy kidneys, and overall well-being.

Consult Top Specialist

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Indrajit Das, General Physician/ Internal Medicine Specialist

Dr. Indrajit Das

General Physician/ Internal Medicine Specialist

4 Years • "MD (Internal medicine) : Gauhati Medical College and Hospital, Guwahati (2018-2021) MD (Pathology) : Gauhati Medical College and Hospital, Guwahati (2012-2015) MBBS (Bachelor of Medicine, Bachelor of Surgery) : Silchar Medical College, Assam (2003-2008) "

Guwahati

Apollo Excelcare Hospital, Guwahati

700

Dr. Haripriya Jagadeesh, General Physician/ Internal Medicine Specialist

Dr. Haripriya Jagadeesh

General Physician/ Internal Medicine Specialist

24 Years • MBBS, AB (Family Physician)

Chennai

Apollo Hospitals Greams Road, Chennai

1500

1500

 

Consult Top Specialist

IMAGE
Dr. Mohammed Kamran, General Practitioner

Dr. Mohammed Kamran

General Practitioner

5 Years • MBBS, FIDM

Nashik

Apollo 24|7 Clinic - Maharashtra, Nashik

609

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Indrajit Das, General Physician/ Internal Medicine Specialist

Dr. Indrajit Das

General Physician/ Internal Medicine Specialist

4 Years • "MD (Internal medicine) : Gauhati Medical College and Hospital, Guwahati (2018-2021) MD (Pathology) : Gauhati Medical College and Hospital, Guwahati (2012-2015) MBBS (Bachelor of Medicine, Bachelor of Surgery) : Silchar Medical College, Assam (2003-2008) "

Guwahati

Apollo Excelcare Hospital, Guwahati

700

Dr. Ramya Hari, General Practitioner

Dr. Ramya Hari

General Practitioner

18 Years • Medical Head & Family Physician, DG Shipping Approved Doctor, Panel Physician - UK Visa Medicals

Chennai

Apollo Medical Centre Kotturpuram, Chennai

1000

Dr. Haripriya Jagadeesh, General Physician/ Internal Medicine Specialist

Dr. Haripriya Jagadeesh

General Physician/ Internal Medicine Specialist

24 Years • MBBS, AB (Family Physician)

Chennai

Apollo Hospitals Greams Road, Chennai

1500

1500

Consult Top Specialist

IMAGE
Dr. Mohammed Kamran, General Practitioner

Dr. Mohammed Kamran

General Practitioner

5 Years • MBBS, FIDM

Nashik

Apollo 24|7 Clinic - Maharashtra, Nashik

609

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Indrajit Das, General Physician/ Internal Medicine Specialist

Dr. Indrajit Das

General Physician/ Internal Medicine Specialist

4 Years • "MD (Internal medicine) : Gauhati Medical College and Hospital, Guwahati (2018-2021) MD (Pathology) : Gauhati Medical College and Hospital, Guwahati (2012-2015) MBBS (Bachelor of Medicine, Bachelor of Surgery) : Silchar Medical College, Assam (2003-2008) "

Guwahati

Apollo Excelcare Hospital, Guwahati

700

Dr. Ramya Hari, General Practitioner

Dr. Ramya Hari

General Practitioner

18 Years • Medical Head & Family Physician, DG Shipping Approved Doctor, Panel Physician - UK Visa Medicals

Chennai

Apollo Medical Centre Kotturpuram, Chennai

1000

Dr. Haripriya Jagadeesh, General Physician/ Internal Medicine Specialist

Dr. Haripriya Jagadeesh

General Physician/ Internal Medicine Specialist

24 Years • MBBS, AB (Family Physician)

Chennai

Apollo Hospitals Greams Road, Chennai

1500

1500

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