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Understanding the Pancreas and Its Functions

Understand the pancreas and its vital functions in digestion and blood sugar regulation. Learn how it supports overall health and the conditions that can affect it.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. J T Hema Pratima MBBS

Last updated on 11th Sep, 2025

Introduction

The pancreas is a small but mighty organ that plays a crucial role in keeping our bodies healthy. Despite its importance, many people don’t know much about it until something goes wrong. If you’ve ever wondered what the pancreas does or why it matters, this article will help you understand its functions, common problems, and how to keep it healthy.

What Is the Pancreas?

The pancreas is a glandular organ located behind the stomach in the upper abdomen. It’s about 6 inches long and shaped like a flat pear. Though small, it has two major jobs:

1. Digestive Function (Exocrine Role) – It produces enzymes that help break down food in the intestines.

2. Hormonal Function (Endocrine Role) – It releases insulin and glucagon, which regulate blood sugar levels.

Without a properly functioning pancreas, digestion and blood sugar control can become difficult, leading to serious health issues.

Consult a Gastroenterologist for the best advice

Dr Bhargav Vuppumalla, General Physician/ Internal Medicine Specialist

Dr Bhargav Vuppumalla

General Physician/ Internal Medicine Specialist

5 Years • MBBS MD GENERAL MEDICINE

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bangalore

Manipal Hospital, Bangalore

850

1000

Dr. Paramesh K N, Gastroenterology/gi Medicine Specialist

Dr. Paramesh K N

Gastroenterology/gi Medicine Specialist

16 Years • MBBS, MS ( General Surgery), DNB ( Surgical Gastroenterology)

Hyderabad

Sprint Diagnostics Centre, Hyderabad

813

750

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Prof. Dr. M S Revathy, Gastroenterology/gi Medicine Specialist

Prof. Dr. M S Revathy

Gastroenterology/gi Medicine Specialist

22 Years • MBBS, MD(GM), DM (Med. Gastro)

Chennai

Apollo Hospitals Greams Road, Chennai

recommendation

91%

(250+ Patients)

1500

1500

Key Functions of the Pancreas

The main functions of the pancreas include:

1. Digestive Enzyme Production

The pancreas helps digest food by releasing enzymes into the small intestine. These enzymes break down:

  • Proteins (with enzymes like trypsin and chymotrypsin)

  • Fats (with lipase)

  • Carbohydrates (with amylase)

If these enzymes aren’t produced properly, you may experience indigestion, bloating, or malnutrition because your body can’t absorb nutrients effectively.

2. Blood Sugar Regulation (Insulin & Glucagon)

The pancreas contains special cells called islets of Langerhans, which produce:

  • Insulin – Lowers blood sugar by helping cells absorb glucose.

  • Glucagon – Raises blood sugar when levels drop too low.

  • When the pancreas doesn’t make enough insulin, diabetes develops, leading to high blood sugar levels.

Common Pancreatic Disorders

Several conditions can affect the pancreas, including:

1. Pancreatitis (Inflammation of the Pancreas)

  • Acute Pancreatitis – Sudden, severe inflammation causing abdominal pain, nausea, and vomiting. Often triggered by gallstones or alcohol abuse.

  • Chronic Pancreatitis – Long-term inflammation leading to permanent damage, poor digestion, and diabetes.

2. Diabetes (Type 1 & Type 2)

  • Type 1 Diabetes – The pancreas stops making insulin due to an autoimmune attack.

  • Type 2 Diabetes – The body becomes resistant to insulin, and the pancreas can’t keep up with demand.

3. Pancreatic Cancer

  • A serious condition where cancerous cells grow in the pancreas. Symptoms often appear late, making early detection crucial.

Symptoms of Pancreas Problems

If your pancreas isn’t working well, you may experience:

  • Severe abdominal pain (radiating to the back)

  • Nausea and vomiting

  • Unexplained weight loss

  • Oily, foul-smelling stools (steatorrhea)

  • Frequent thirst and urination (signs of diabetes)

If you notice these symptoms, consult a doctor for proper evaluation.

How to Keep Your Pancreas Healthy

A healthy lifestyle can protect your pancreas and prevent complications:

1. Eat a Balanced Diet

  • Limit fatty, fried, and processed foods (they strain the pancreas).

  • Increase fibre (whole grains, fruits, vegetables).

  • Stay hydrated (helps digestion).

2. Avoid Excessive Alcohol & Smoking

Alcohol abuse is a leading cause of pancreatitis, and smoking increases pancreatic cancer risk.

3. Maintain a Healthy Weight

Obesity increases diabetes risk, which stresses the pancreas.

4. Exercise Regularly

Physical activity helps regulate blood sugar levels and reduces diabetes risk.

5. Get Regular Check-ups

If you have a family history of diabetes or pancreatic disease, regular screenings can help catch problems early.

When to See a Doctor

It’s best to consult a healthcare provider if you experience:

  • Persistent abdominal pain

  • Unexplained weight loss

  • Signs of diabetes (excessive thirst, frequent urination)

  • Digestive problems (oily stools, bloating)

Final Thoughts

The pancreas may be small, but its role in digestion and blood sugar control is vital. By understanding its functions and taking steps to protect it, you can maintain better overall health. If you have concerns about your pancreas, don’t hesitate to seek medical advice; early intervention can prevent serious complications.

Consult a Gastroenterologist for the best advice

Dr Bhargav Vuppumalla, General Physician/ Internal Medicine Specialist

Dr Bhargav Vuppumalla

General Physician/ Internal Medicine Specialist

5 Years • MBBS MD GENERAL MEDICINE

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bangalore

Manipal Hospital, Bangalore

850

1000

Dr. Paramesh K N, Gastroenterology/gi Medicine Specialist

Dr. Paramesh K N

Gastroenterology/gi Medicine Specialist

16 Years • MBBS, MS ( General Surgery), DNB ( Surgical Gastroenterology)

Hyderabad

Sprint Diagnostics Centre, Hyderabad

813

750

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Prof. Dr. M S Revathy, Gastroenterology/gi Medicine Specialist

Prof. Dr. M S Revathy

Gastroenterology/gi Medicine Specialist

22 Years • MBBS, MD(GM), DM (Med. Gastro)

Chennai

Apollo Hospitals Greams Road, Chennai

recommendation

91%

(250+ Patients)

1500

1500

Consult a Gastroenterologist for the best advice

Dr Bhargav Vuppumalla, General Physician/ Internal Medicine Specialist

Dr Bhargav Vuppumalla

General Physician/ Internal Medicine Specialist

5 Years • MBBS MD GENERAL MEDICINE

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bangalore

Manipal Hospital, Bangalore

850

1000

Dr. Paramesh K N, Gastroenterology/gi Medicine Specialist

Dr. Paramesh K N

Gastroenterology/gi Medicine Specialist

16 Years • MBBS, MS ( General Surgery), DNB ( Surgical Gastroenterology)

Hyderabad

Sprint Diagnostics Centre, Hyderabad

813

750

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Prof. Dr. M S Revathy, Gastroenterology/gi Medicine Specialist

Prof. Dr. M S Revathy

Gastroenterology/gi Medicine Specialist

22 Years • MBBS, MD(GM), DM (Med. Gastro)

Chennai

Apollo Hospitals Greams Road, Chennai

recommendation

91%

(250+ Patients)

1500

1500

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