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Understanding Orthopaedic Oncology: Bone Tumour Guide

A comprehensive guide to orthopaedic oncology, explaining benign and malignant bone tumours, symptoms, diagnosis, and advanced treatment options.

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Written by Dr. Siri Nallapu

Reviewed by Dr. Md Yusuf Shareef MBBS

Last updated on 18th Sep, 2025

Introduction

Discovering a lump or experiencing persistent bone pain can be a frightening experience, immediately bringing the word "cancer" to mind. However, the field of medicine dedicated to these concerns, orthopaedic oncology, offers hope and highly advanced solutions. This specialised branch focuses on the diagnosis and treatment of both benign (non-cancerous) and malignant (cancerous) tumours of the bones, muscles, and soft tissues. While bone cancers themselves are rare, understanding them is crucial for early detection and effective treatment. This guide will demystify orthopaedic oncology, walking you through the different types of tumours, common symptoms to watch for, the detailed diagnostic process, and the groundbreaking treatments available today. Our goal is to empower you with knowledge, so you can take informed steps towards health and wellness.

Benign vs. Malignant: Not Every Lump is Cancer

The most critical concept in orthopaedic oncology is understanding that not every tumour is cancerous. In fact, benign tumours are far more common.

Benign Tumours: These are non-cancerous growths. They do not spread to other parts of the body (metastasise) and are usually not life-threatening. However, they can still weaken bone structure, cause pain, or grow large enough to press on nerves or muscles, requiring treatment.

Malignant Tumours: These are cancerous growths. They can invade and destroy surrounding healthy tissue and have the potential to metastasise, most commonly to the lungs or other bones. Malignant musculoskeletal tumours are known as sarcomas.

Common Types of Benign Bone Tumours

Some frequently diagnosed benign tumours include osteochondromas (the most common, often occurring near growth plates), giant cell tumours (which can be aggressive locally), and enchondromas (cartilage cysts within the bone). While often monitored, some may require surgery if they cause symptoms.

Common Types of Malignant Bone Tumours (Sarcomas)

The most prevalent primary bone cancers are osteosarcoma (common in teenagers and young adults, often around the knee or arm), Ewing sarcoma (affecting children and young adults, often in pelvis, legs, or ribs), and chondrosarcoma (a cancer of cartilage, more common in older adults). Understanding the specific type of musculoskeletal tumour is essential for determining the correct treatment plan.

Soft Tissue Sarcomas: Beyond the Bone

Orthopaedic oncologists also treat cancers that originate in soft tissues like muscles, fat, nerves, and blood vessels. These are known as soft tissue sarcomas and can occur anywhere in the body.

Recognising the Signs: Symptoms of Musculoskeletal Tumours

Early detection is key. While many symptoms can be caused by common injuries like sprains or arthritis, it is important to see a doctor if you experience:

  • Persistent Pain: Pain in a bone or joint that is constant, worsens at night, and is not related to physical activity.

  • Swelling or a Lump: A noticeable mass or swelling, which may or may not be painful to the touch.

  • Unexplained Fractures: A bone that breaks from a minor injury or for no apparent reason (a "pathological fracture").

  • Limited Mobility: Difficulty moving a joint or limb normally.

  • Unexpected Weight Loss or Fever: These systemic symptoms are less common but can occur.

If you have a lump that is growing or pain that persists beyond two weeks, consult a doctor online with Apollo24|7 for a preliminary evaluation and to determine if you need a physical visit to a specialist.

Consult a Oncologist for Personalised Advice

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

How is a Bone Tumour Diagnosed? The Step-by-Step Process

Diagnosis is a multi-step process designed to be thorough and accurate.

The Initial Physical Exam and History

Your doctor will discuss your general health and symptoms and physically examine the affected area, checking for pain, tenderness, swelling, and changes in the skin.

Imaging Tests: X-Rays, MRI, and CT Scans

  • X-Rays: The first step. They can show the location, size, and shape of a bone tumour and whether it has caused bone damage.

  • MRI: Provides detailed images of soft tissues, muscles, and bones. It is excellent for determining the exact extent of a tumour and its relationship to nerves and blood vessels.

  • CT Scan: Often used to check if a cancerous tumour has spread to the chest or other organs.

  • PET Scan: Sometimes used to stage cancer and see if it has metastasised.

The Biopsy: The Definitive Diagnostic Tool

This is the only way to confirm whether a tumour is benign or malignant. A specialist removes a small sample of tissue from the tumour, which is then analysed by a pathologist. This confirms the diagnosis and helps grade the tumour's aggressiveness. It is a critical procedure that should be performed by an experienced orthopaedic oncologist to ensure proper technique and not affect future treatment options.

Modern Treatment Options in Orthopaedic Oncology

Treatment is highly personalised and involves a multidisciplinary team of surgeons, medical oncologists, and radiation oncologists.

Limb-Salvage Surgery: The Gold Standard

Gone are the days when amputation was the only option. Today, limb-salvage surgery is the most common procedure. The surgeon removes the cancerous section of bone and surrounding tissue and reconstructs the limb. This can be done using:

  • Metal Prosthesis: An artificial joint or segment.

  • Bone Graft: Using bone from another part of your body (autograft) or from a donor (allograft).

The goal is to remove the cancer completely while preserving as much limb function and appearance as possible.

Chemotherapy and Radiation Therapy

  • Chemotherapy: Uses powerful drugs to kill cancer cells. It is often used before surgery (neoadjuvant) to shrink a tumour and after surgery (adjuvant) to kill any remaining cells.

  • Radiation Therapy: Uses high-energy beams to destroy cancer cells. It is more commonly used for certain types of tumours like Ewing sarcoma or for tumours that are difficult to remove completely with surgery.

New Frontiers: Targeted Therapy and Immunotherapy

These are precision medicine approaches. Targeted therapy uses drugs that specifically attack cancer cells based on their genetic mutations, often with fewer side effects than traditional chemo. Immunotherapy helps your own immune system recognise and fight cancer cells. These are areas of active research in orthopaedic oncology.

Conclusion: The Importance of Specialised Care

A diagnosis involving a bone or soft tissue tumour is undoubtedly challenging, but the field of orthopaedic oncology has made extraordinary strides. From precise diagnostic tools like MRI and biopsy to revolutionary limb-salvage surgery techniques and new systemic therapies, the outlook for patients is brighter than ever. The most critical step is seeking care from a dedicated multidisciplinary team at a specialised centre. They have the experience to provide an accurate diagnosis and create a comprehensive, personalised treatment plan aimed at curing the disease while maximising your quality of life. Remember, knowledge is your first line of defence. If you have concerns, do not hesitate to seek expert medical advice. If your condition requires further investigation, you can book a physical visit to an orthopaedic specialist with Apollo24|7 to get the expert care you need.

Consult a Oncologist for Personalised Advice

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

Consult a Oncologist for Personalised Advice

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

1000

No Booking Fees

Dr. Sanchayan Mandal, Oncologist

Dr. Sanchayan Mandal

Oncologist

17 Years • MBBS, DNB Raditherapy, DrNB Medical Oncology

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

1500

Dr.sanchayan Mandal, Oncologist

Dr.sanchayan Mandal

Oncologist

17 Years • MBBS, DrNB( MEDICAL ONCOLOGY), DNB (RADIOTHERAPY),ECMO. PDCR. ASCO

Kolkata

Dr. Sanchayan Mandal Oncology Clinic, Kolkata

1500

1500

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

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Frequently Asked Questions

What's the difference between an orthopaedic oncologist and a regular oncologist?

An orthopaedic oncologist is a surgeon specially trained to diagnose and surgically treat cancers of the bones and soft tissues. A medical oncologist specialises in treating cancer with chemotherapy, targeted therapy, and other drugs. They work closely together as a team.

Are bone tumours hereditary?

Most bone cancers are not directly inherited. However, there are rare genetic syndromes (like Li-Fraumeni syndrome or hereditary retinoblastoma) that can increase a person's risk of developing sarcomas.

What is the recovery time after limb-salvage surgery?

Recovery is a process. Hospital stay is typically several days to a week. Initial healing takes 6–12 weeks, but full recovery and rehabilitation to regain strength and mobility can take 6 months to a year or more, involving extensive physical therapy.

Can benign bone tumours turn into cancer?

The vast majority of benign tumours do not become cancerous. However, certain types, like multiple enchondromatosis, have a very small increased risk of transforming into a chondrosarcoma. Regular monitoring by a specialist is advised for such conditions.

Is the pain from a bone tumour constant?

Often, yes. Unlike pain from an injury that may come and go, pain from a malignant bone tumour tends to be persistent, can worsen at night, and may not be relieved by rest or over-the-counter pain medication.