Vitamin B6 Deficiency Overview and Effects
Learn about Vitamin B6 deficiency, its symptoms, causes, and health impacts. Discover how to prevent and manage it through diet, supplements, and lifestyle changes for better overall wellness.
Written by Dr. Dhankecha Mayank Dineshbhai
Reviewed by Dr. Siri Nallapu MBBS
Last updated on 26th Nov, 2025
Introduction
Vitamins are essential nutrients that our bodies need to function properly. Among them, Vitamin B6 (Pyridoxine) plays a crucial role in keeping our brain, nerves, and immune system healthy. However, when we don’t get enough of it, Vitamin B6 deficiency can occur, leading to various health problems.
In this article, we’ll explore what Vitamin B6 deficiency is, its symptoms, causes, and how you can manage or prevent it.
What is Vitamin B6 Deficiency?
Vitamin B6 is a water-soluble vitamin, meaning our body doesn’t store it for long, and we need a regular supply through food or supplements. When intake is insufficient or absorption is poor, deficiency occurs, affecting multiple bodily functions.
Why is Vitamin B6 Important?
- Helps in brain development and function
- Supports nerve function and mood regulation
- Aids in protein metabolism and red blood cell production
- Strengthens the immune system
Signs and Symptoms of Vitamin B6 Deficiency
A mild deficiency may not show obvious symptoms, but prolonged deficiency can lead to:
- 1. Skin Problems – Rashes, cracks around the mouth, or flaky skin.
- 2. Mood Changes – Depression, anxiety, irritability, or confusion.
- 3. Weak Immune System – Frequent infections or slow healing.
- 4. Fatigue & Low Energy – Feeling unusually tired despite adequate rest.
- 5. Nerve Issues – Tingling or numbness in hands and feet (peripheral neuropathy).
- 6. Anaemia – Due to impaired haemoglobin production.
- 7. Seizures (in severe cases) – Especially in infants.
If you experience these symptoms, consult a doctor for proper diagnosis.
What Causes Vitamin B6 Deficiency?
Several factors can lead to low Vitamin B6 levels:
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1. Poor Diet
- Not eating enough Vitamin B6-rich foods like poultry, fish, bananas, potatoes, and nuts.
- Excessive consumption of processed foods lacking nutrients.
2. Digestive Disorders
Conditions like celiac disease, Crohn’s disease, or ulcerative colitis can impair nutrient absorption.
3. Alcohol Dependence
Alcohol interferes with Vitamin B6 absorption and metabolism.
4. Certain Medications
Some drugs (like anti-tuberculosis, anti-seizure, or diuretics) can reduce B6 levels.
5. Kidney Disease & Autoimmune Disorders
These conditions may increase Vitamin B6 loss from the body.
How Does Vitamin B6 Deficiency Affect Your Health?
Long-term deficiency can lead to:
- Neurological Issues – Nerve damage, memory problems, and even seizures.
- Heart Disease Risk – Due to increased homocysteine levels (a harmful amino acid).
- Weakened Immunity – Making you prone to infections.
- Anaemia & Fatigue – Affecting daily productivity.
How to Manage & Prevent Vitamin B6 Deficiency?
1. Eat Vitamin B6-Rich Foods
Include these in your diet:
- Meat & Fish – Chicken, turkey, salmon, tuna
- Vegetables – Spinach, potatoes, carrots
- Fruits – Bananas, avocados
- Nuts & Seeds – Pistachios, sunflower seeds
- Whole Grains – Brown rice, oats
2. Consider Supplements (if needed)
If diet alone isn’t enough, supplements may help (always consult a doctor first).
3. Limit Alcohol & Processed Foods
Alcohol depletes B6, while junk food lacks essential nutrients.
4. Manage Underlying Conditions
If digestive or kidney issues are causing deficiency, proper treatment is necessary.
5. Regular Health Check-ups
Blood tests can detect deficiencies early.
When to See a Doctor?
If you experience persistent symptoms like fatigue, mood swings, or nerve issues, it’s best to get tested. Apollo 24|7 offers easy blood tests and expert consultations to help diagnose and manage Vitamin B6 deficiency.
Book a test or consult a doctor today to ensure your body gets the nutrients it needs!
Final Thoughts
Vitamin B6 deficiency is preventable and manageable with the right diet and lifestyle changes. By eating a balanced diet, avoiding excessive alcohol, and addressing underlying health conditions, you can maintain optimal Vitamin B6 levels and support your overall well-being.
Consult Top Specialist
Consult Top Specialist
Dr Suseela
General Physician
5 Years • MBBS
Bengaluru
Apollo Medical Center, Marathahalli, Bengaluru
Dr. Mainak Baksi
General Practitioner
13 Years • MBBS , MD (MPH)
Howrah
Mainak Baksi Clinic, Howrah
(50+ Patients)
Dr. Rajib Ghose
General Physician/ Internal Medicine Specialist
25 Years • MBBS
East Midnapore
VIVEKANANDA SEBA SADAN, East Midnapore
Dr. Sougata Kumar
General Practitioner
8 Years • MBBS
East Midnapore
VIVEKANANDA SEBA SADAN, East Midnapore
Dr. Tapabrata Ray
General Physician/ Internal Medicine Specialist
4 Years • MBBS,DGM,CPMeC,ACMDC
Kolkata
MCR SUPER SPECIALITY POLY CLINIC & PATHOLOGY, Kolkata
Consult Top Specialist
Dr Suseela
General Physician
5 Years • MBBS
Bengaluru
Apollo Medical Center, Marathahalli, Bengaluru
Dr. Mainak Baksi
General Practitioner
13 Years • MBBS , MD (MPH)
Howrah
Mainak Baksi Clinic, Howrah
(50+ Patients)
Dr. Rajib Ghose
General Physician/ Internal Medicine Specialist
25 Years • MBBS
East Midnapore
VIVEKANANDA SEBA SADAN, East Midnapore
Dr. Sougata Kumar
General Practitioner
8 Years • MBBS
East Midnapore
VIVEKANANDA SEBA SADAN, East Midnapore
Dr. Tapabrata Ray
General Physician/ Internal Medicine Specialist
4 Years • MBBS,DGM,CPMeC,ACMDC
Kolkata
MCR SUPER SPECIALITY POLY CLINIC & PATHOLOGY, Kolkata
