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Endometriosis: Causes, Symptoms, and Effective Treatments

Endometriosis is a painful and chronic condition that causes menstrual and fertility issues. Read more to know about its causes, symptoms, and treatment options.

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Last updated on 3rd Jul, 2025

Endometriosis is a condition in which endometrium (tissues similar to the uterus lining) grows outside one's uterus. It affects nearly 10% of women who are of reproductive age and causes multiple issues, including infertility, period pain, and others.

Keep reading to learn more about its cause, symptoms, and treatment options!

Causes of Endometriosis

Though the actual causes of endometriosis are yet not discovered, here are some of the possible factors that can lead to such conditions:

  • It is found that some family members are more likely to be affected by endometriosis than others. Thus, genetic factors can cause such issues.

  • During the menstruation cycle, endometrial tissues may enter one's fallopian tubes instead of leaving the body through menstrual blood.

  • The lymphatic system or blood can transport endometrial tissues to different body parts.

  • After surgeries like hysterectomy or C-sections, endometrial cells often get attached to the abdomen walls or other body parts.

  • Sometimes, other cells of the body may transform into endometrial cells. These cells grow outside one’s endometrium. 

Symptoms of Endometriosis

Here are some of the most common symptoms of endometriosis:

1. Painful Intercourse

One of the common symptoms of endometriosis is experiencing pain after or during sex.

2. Pain During Urination or Bowel Movements

One can feel pain while urinating or bowel movements during or before menstrual cycle if they have endometriosis.

3. Period Pain

Endometriosis can lead to period cramps and pelvic pain accompanied by stomach and back pain that starts before the menstruation and continues for days.

4. Infertility

In some individuals, endometriosis has been diagnosed first while testing for infertility. Thus, infertility is considered as a symptom of this condition.

5. Too Much Bleeding

Heavy menstrual flow can also indicate conditions like endometriosis.

Some other symptoms of endometriosis include the following before menstrual cycle:
 

  • Constipation

  • Nausea

  • Fatigue

  • Bloating

  • Diarrhoea, etc.

Risk Factors

Here are the potential risk factors of endometriosis:

  • Low BMI

  • Family history

  • First period at a young age

  • Heavy periods lasting over a week

  • Less than 28 days gap between two menstrual cycles

  • Menopause at an older age

  • High levels of estrogen

  • A health condition that prevents normal blood flow during menstruation

  • Nulliparous (one who has not given birth either by choice or some other reason), etc.

Diagnosis of Endometriosis

As endometriosis symptoms are similar to other health conditions, doctors often ask for the following tests for accurate diagnosis:

1. Physical Test

A physical test refers to the pelvic exam in which the doctors look into the cervix and vagina using a speculum and light. They also check for scars or cysts behind the uterus by manually feeling one's abdomen.

2. Ultrasound

Doctors often ask for an abdominal or transvaginal ultrasound to get a detailed image of the reproductive organs. It helps check if the cysts in one's reproductive organs are associated with endometriosis.

3. Laparoscopy

It is the best method to check for endometriosis. Doctors can view endometriosis directly in this process through a minor surgery. 

Treatment Options

Doctors can implement any of these treatments for endometriosis based on the severity of one’s condition:

1. Medications

NSAIDs (nonsteroidal anti-inflammatory drugs) help reduce the pain of endometriosis. Doctors prescribe medicines to manage the endometriosis symptoms.

2. Hormonal Therapy

Some hormonal therapies like the following can help reduce the pain and suppress one's menstrual cycle:

  • GnRH Agonists

Gonadotropin-releasing hormone agonists or antagonists are a medicine that stops the menstruation-causing hormone to relieve endometriosis pain. 

  • Birth Control

These pills are available in combination therapy of progestin and estrogen or only progestin. It reduces the period pain and heavy flow. Birth controls are available in various forms like vaginal rings, birth control pills, implants, patches, birth control shots, etc.

  • Danazol

This medicine prevents the body from producing period-causing hormones. Individuals taking this medicine to treat endometriosis may not get menstruation or experience it occasionally.
These medicines may relieve the pain caused due to endometriosis. However, these are not permanent solutions as one will get back the symptoms as soon as they stop taking medicines.

3. Surgery

Surgical procedures like the following can be effective in curing endometriosis completely:

  • Laparoscopic Surgery

In laparoscopic surgery, the surgeon inserts a laparoscope into one's body by making a small cut in the abdomen. The laparoscope contains an HD (high definition) camera to provide a clear picture of the organs inside one’s body, helping the surgeon to identify endometriosis.

  • Hysterectomy

This refers to the removal of ovaries and uterus. Doctors suggest a hysterectomy in case of severe endometriosis. 

Lifestyle and Home Remedies

The following lifestyle habits and home remedies can provide relief from endometriosis:

1. Proper Diet

Eating fresh vegetables and fruits and reducing the intake of red meat can control estrogen production, lowering the risks of endometrial tissue growth. As per studies, individuals who consume more omega-3 fatty acids are 22% less prone to endometriosis.

Trans fats increase the chances of endometriosis by 48%. So, individuals should avoid foods containing trans fats and include those containing omega-3 fatty acids. Individuals should also keep a check on alcohol and caffeine consumption to lower the risks of endometriosis.

2. Regular Exercise

Daily workouts improve blood circulation in one's body, allowing oxygen and nutrients to flow to all parts of the body. It keeps the estrogen level in check, reducing period cramps and heavy flow.
A healthy reproductive system can reduce the risks of endometriosis. Besides, physical activities help release endorphins (a brain chemical) that reduce stress and relieve pain. 

3. Stress Management

Meditation, yoga, and other low-intensity workouts can also help reduce stress and manage endometriosis by stretching the muscles and tissues in one's pelvis. 

4. Support Groups

Individuals can also join support groups to seek emotional support from people going through endometriosis or fertility issues. Sharing experiences and feelings with each other can relieve stress and encourage individuals to fight against their endometriosis condition. 

Complications and Long-term Outlook

Neglecting the symptoms of endometriosis and delay in treatment can lead to the following complications in an individual:

  • Infertility

Endometriosis can damage the sperm and prevent it from uniting with the egg, leading to infertility issues. It may also block the fallopian tube through which the egg travels to meet a sperm cell for fertilisation.

  • Cancer

In some cases, endometriosis may lead to ovarian cancer or a rare type of cancer called endometriosis-associated adenocarcinoma. 

Apart from these chronic issues, endometriosis may also cause the following complications:

  • Chest pain or breathing difficulties, such as endometriosis, can affect the diaphragm or lungs.

  • Endometriotic tissues growing near the intestine, bladder, or rectum can cause intense pain while one uses the bathroom. One may also notice blood while pooping or peeing.

Current Research and Future Directions

Recent research on endometriosis focuses on understanding its complex pathogenesis, including genetic, hormonal, and immune factors. There is a growing interest in developing novel, estrogen-sparing treatments that effectively manage pain and improve fertility outcomes.
Future studies aim to assess clinically relevant endpoints and explore new therapeutic targets like microRNAs and inflammatory mediators to enhance treatment efficacy.

Conclusion

To manage endometriosis effectively, one must understand its symptoms, risk factors, and diagnosis process. Timely diagnosis followed by appropriate treatment strategies can significantly improve the quality of life for those affected by this chronic condition.

With ongoing research efforts to uncover new insights into its pathophysiology and treatment modalities, there is hope for advancements. It will possibly enhance care for women suffering from endometriosis in the future.

Consult Top Gynaecologist

Dr Swatika Kumari, Obstetrician and Gynaecologist

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Consult Top Gynaecologist

Dr Swatika Kumari, Obstetrician and Gynaecologist

Dr Swatika Kumari

Obstetrician and Gynaecologist

19 Years • MBBS, DGO, DNB Obstetrics & Gynaecology

Nashik

Apollo 24|7 Clinic - Maharashtra, Nashik

649

64 Cashback

Dr. Priyanka Surisetty, Obstetrician and Gynaecologist

Dr. Priyanka Surisetty

Obstetrician and Gynaecologist

8 Years • MBBS, DGO

Visakhapatnam

Apollo 24|7 Clinic - Andhra Pradesh, Visakhapatnam

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Dr. Shailaja L, Obstetrician and Gynaecologist

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Nulife multispeciality, Dombivli

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Dr. Parul Sharma, Obstetrician and Gynaecologist

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