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What Is The Most Common Complication After Angioplasty?

Restenosis, or re-narrowing of the artery, is the most common complication after angioplasty. Learn why it happens, how to recognise it, and steps you can take to prevent it.

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Written by Dr.Sonia Bhatt

Last updated on 3rd Jul, 2025

Introduction

Angioplasty is a common and life-saving procedure used to open blocked or narrowed arteries, usually in the heart (coronary arteries). While it is generally safe and effective, like any medical procedure, it can have some complications. Understanding these risks can help patients stay informed and take necessary precautions for a smooth recovery.

The Most Common Complication: Restenosis

The most frequent complication after angioplasty is restenosis, which means the treated artery becomes narrow again over time. This happens because the artery walls can sometimes respond to the procedure by forming excess scar tissue, leading to a recurrence of blockages.

1. Why Does Restenosis Happen?

Restenosis typically occurs due to the body’s natural healing response. Here are the main reasons:

1. Natural Healing Response – After angioplasty, the body tries to heal the treated area, sometimes causing excessive tissue growth inside the artery.

2. Stent-Related Factors – If a stent, a small mesh tube, is placed, the body may react by forming scar tissue around it, leading to re-narrowing.

3. Underlying Conditions – Patients with diabetes, high cholesterol, or those who smoke are at higher risk.

2. Symptoms of Restenosis

If restenosis occurs, symptoms may resemble those before angioplasty, such as:

  • Chest pain or discomfort (angina)

  • Shortness of breath

  • Fatigue during physical activity

If you experience these symptoms, consult your doctor immediately.

Consult Top Specialists for Personalised Heart Health Advice

Dr. Praveen Kumar, Cardiologist

Dr. Praveen Kumar

Cardiologist

25 Years • MBBS, MD (Medicine), DM (Cardiology)

Ghaziabad

Navaanya wellness, Ghaziabad

1000

800

Dr. Sumanta Chatterjee, Cardiologist

Dr. Sumanta Chatterjee

Cardiologist

12 Years • MBBS,MD General Medicine,DM Cardiology

Kolkata

HealthYou Speciality Clinic & Diagnostics., Kolkata

recommendation

90%

(25+ Patients)

1100

1100

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Dr. Dixit Garg, Cardiologist

Dr. Dixit Garg

Cardiologist

10 Years • MBBS , DNB (General medicine) , DNB (cardiology)

Gurugram

Smiles & Hearts, Gurugram

800

No Booking Fees

Other Possible Complications After Angioplasty

While restenosis is the most common, other complications may include:

1. Bleeding or Bruising at the Catheter Site – Mild bruising is normal, but excessive bleeding should be reported.

2. Blood Clots – Rarely, clots can form inside the stent, leading to a sudden blockage (stent thrombosis).

3. Infection – Though uncommon, infections at the insertion site can occur.

4. Allergic Reaction to Contrast Dye – Some patients may react to the dye used during the procedure.

5. Kidney Problems (Contrast-Induced Nephropathy) – The dye can sometimes affect kidney function, especially in patients with pre-existing kidney issues.

How to Reduce the Risk of Complications

Fortunately, many complications can be prevented or managed with proper care. Here’s what you can do:

1. Take Prescribed Medications

One of the most important steps in preventing complications is to take your medications exactly as prescribed. Never skip or stop any medicine without consulting your doctor.

  • Blood Thinners (Antiplatelets) – Drugs like aspirin or clopidogrel prevent clots from forming inside the stent. Never stop these without consulting your doctor.

  • Cholesterol-Lowering Drugs (Statins) – These help keep arteries clear.

  • Blood Pressure & Diabetes Medications – Managing these conditions reduces the risk of restenosis.

2. Follow a Heart-Healthy Diet

What you eat plays a crucial role in recovery and overall heart health. A balanced diet not only helps your heart heal but also prevents future complications.

  • Eat more fruits, vegetables, whole grains, and lean proteins.

  • Reduce salt, sugar, and unhealthy fats.

  • Avoid processed foods and excessive red meat.

3. Stay Active (With Doctor’s Approval)

Physical activity helps maintain heart strength—but only when done safely. Gentle movement improves circulation and supports overall well-being.

  • Light exercises like walking can improve heart health.

  • Avoid strenuous activities immediately after the procedure.

4. Quit Smoking & Limit Alcohol

Eliminating smoking and limiting alcohol are critical for heart health post-angioplasty.

  • Quit smoking to reduce the risk of re-narrowing and other cardiac issues.

  • If you drink alcohol, do so in moderation and only if your doctor approves.

5. Regular Follow-Ups

Ongoing care is key to ensuring a smooth recovery and catching any early signs of trouble. Regular monitoring can help you stay on track and reduce long-term risks.

  • Attend all scheduled check-ups to monitor heart health.

  • Report any unusual symptoms promptly.

When to Seek Immediate Medical Help

While most complications are manageable, some require urgent attention. Contact your doctor or go to the hospital if you experience:

  • Severe chest pain

  • Sudden shortness of breath

  • Heavy bleeding or swelling at the catheter site

  • Fever or signs of infection

Conclusion

Angioplasty is a highly effective treatment for blocked arteries, but restenosis, re-narrowing of the artery, remains the most common complication. By following your doctor’s advice, taking medications as prescribed, and maintaining a healthy lifestyle, you can significantly reduce risks and enjoy a better quality of life.

If you have concerns about your recovery or need a follow-up consultation, Apollo24|7 offers expert cardiology care with easy online appointments. Stay proactive about your heart health—book a consultation today!

Consult Top Cardiologists

Dr. Praveen Kumar, Cardiologist

Dr. Praveen Kumar

Cardiologist

25 Years • MBBS, MD (Medicine), DM (Cardiology)

Ghaziabad

Navaanya wellness, Ghaziabad

1000

800

Dr. Sumanta Chatterjee, Cardiologist

Dr. Sumanta Chatterjee

Cardiologist

12 Years • MBBS,MD General Medicine,DM Cardiology

Kolkata

HealthYou Speciality Clinic & Diagnostics., Kolkata

recommendation

90%

(25+ Patients)

1100

1100

No Booking Fees

Dr. Dixit Garg, Cardiologist

Dr. Dixit Garg

Cardiologist

10 Years • MBBS , DNB (General medicine) , DNB (cardiology)

Gurugram

Smiles & Hearts, Gurugram

800

No Booking Fees

Consult Top Specialists for Personalised Heart Health Advice

Dr. Praveen Kumar, Cardiologist

Dr. Praveen Kumar

Cardiologist

25 Years • MBBS, MD (Medicine), DM (Cardiology)

Ghaziabad

Navaanya wellness, Ghaziabad

1000

800

Dr. Sumanta Chatterjee, Cardiologist

Dr. Sumanta Chatterjee

Cardiologist

12 Years • MBBS,MD General Medicine,DM Cardiology

Kolkata

HealthYou Speciality Clinic & Diagnostics., Kolkata

recommendation

90%

(25+ Patients)

1100

1100

No Booking Fees

Dr. Amit. A. Bharadiya, Cardiologist

Dr. Amit. A. Bharadiya

Cardiologist

12 Years • MBBS, MD General Medicine, DNB Cardiology

Maharashtra

Surabhi Hospital, Maharashtra, Maharashtra

1100

90 Cashback

Dr. Nataraja Setty, Cardiologist

Dr. Nataraja Setty

Cardiologist

21 Years • MBBS, MD (General Medicine), DM (Cardiology)

Bengaluru

Sapphire heart care clinic, Bengaluru

700

No Booking Fees

Dr. Dixit Garg, Cardiologist

Dr. Dixit Garg

Cardiologist

10 Years • MBBS , DNB (General medicine) , DNB (cardiology)

Gurugram

Smiles & Hearts, Gurugram

800

No Booking Fees

Consult Top Cardiologists

Dr. Praveen Kumar, Cardiologist

Dr. Praveen Kumar

Cardiologist

25 Years • MBBS, MD (Medicine), DM (Cardiology)

Ghaziabad

Navaanya wellness, Ghaziabad

1000

800

Dr. Sumanta Chatterjee, Cardiologist

Dr. Sumanta Chatterjee

Cardiologist

12 Years • MBBS,MD General Medicine,DM Cardiology

Kolkata

HealthYou Speciality Clinic & Diagnostics., Kolkata

recommendation

90%

(25+ Patients)

1100

1100

No Booking Fees

Dr. Amit. A. Bharadiya, Cardiologist

Dr. Amit. A. Bharadiya

Cardiologist

12 Years • MBBS, MD General Medicine, DNB Cardiology

Maharashtra

Surabhi Hospital, Maharashtra, Maharashtra

1100

90 Cashback

Dr. Nataraja Setty, Cardiologist

Dr. Nataraja Setty

Cardiologist

21 Years • MBBS, MD (General Medicine), DM (Cardiology)

Bengaluru

Sapphire heart care clinic, Bengaluru

700

No Booking Fees

Dr. Dixit Garg, Cardiologist

Dr. Dixit Garg

Cardiologist

10 Years • MBBS , DNB (General medicine) , DNB (cardiology)

Gurugram

Smiles & Hearts, Gurugram

800

No Booking Fees

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