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Guide to Know All About Hpv Vaccines

Learn all about the HPV vaccine—a powerful tool for cancer prevention. Our guide covers who should get vaccinated, the recommended schedule, and debunks common myths to help you make an informed decision.

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Written by Dr. Siri Nallapu

Reviewed by Dr. Vasanthasree Nair MBBS

Last updated on 15th Sep, 2025

Hpv Vaccines

​Imagine a single shot that could protect you from multiple types of cancer. It’s not science fiction; it’s the reality of the HPV vaccine. Human papillomavirus (HPV) is an incredibly common virus linked to various cancers, including cervical, throat, and anal cancer. This vaccine is a powerful tool in preventing these cancers before they even have a chance to develop. Whether you're a parent considering the vaccine for your child or an adult evaluating your options, understanding the facts is the first step toward making an informed health decision. This comprehensive guide will walk you through everything you need to know about HPV vaccines—from how they work and who should get them to addressing common concerns and myths. Let's explore how this medical breakthrough can be a crucial part of your long-term health strategy.

​What is HPV and Why Should You Care?

​The Surprising Prevalence of HPV

​HPV, or human papillomavirus, is the most common sexually transmitted infection (STI) globally. Nearly all sexually 
active men and women will get at least one type of HPV at some point in their lives. There are over 100 varieties of HPV, and while most are low-risk and clear from the body on their own, a handful are considered high-risk and can 
lead to serious health problems.

​From Infection to Cancer: Understanding the Risk

​The danger of high-risk HPV strains lies in their ability to cause changes in cells that can lead to cancer over time. 
Persistent infection with these strains is responsible for:

  • ​Over 90% of cervical cancers.
  • ​A significant percentage of cancers of the vagina, vulva, penis, and anus.
  • ​Approximately 70% of oropharyngeal cancers (back of the throat, including the base of the tongue and tonsils).

​Low-risk strains, while not cancer-causing, can cause genital warts. The goal of the HPV vaccine is to prevent infection from the most common high-risk and low-risk strains, effectively stopping the problem at its source.

​The HPV Vaccine: A Shield Against Cancer

​How Does the HPV Vaccine Work?

​The HPV vaccine is a prophylactic vaccine, meaning it is designed to prevent a future disease. It works by introducing virus-like particles (VLPs) into the body. These VLPs are empty shells that mimic the HPV virus but contain no viral DNA, making them completely non-infectious and unable to cause disease. Your immune system recognizes these VLPs as a threat and produces antibodies to fight them. This process creates a "memory" in your immune system, so if you are ever exposed to the real HPV virus in the future, your body can mount a swift and effective defense, preventing infection and, consequently, the cancers it can cause.

​Gardasil 9: The Current Vaccine in Use

​Currently, Gardasil 9 is the only HPV vaccine available in most parts of the world, including India and the United 
States. It is highly effective at protecting against nine strains of HPV:

  • ​Types 16 and 18: The two highest-risk strains, responsible for about 80% of cervical cancers.
  • ​Types 6 and 11: Which cause about 90% of genital warts.
  • ​Types 31, 33, 45, 52, and 58: Other high-risk strains that contribute to cervical and other HPV-related cancers.

​By targeting these nine types, Gardasil 9 prevents the vast majority of HPV-driven cancers and diseases.

​Who Should Get the HPV Vaccine and When?

​The Ideal Age: Preteens and Early Teens

​The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) recommend routine HPV vaccination for both boys and girls at age 11 or 12. The reason for this early age is that the vaccine is most effective when administered before any exposure to HPV. The immune response to the vaccine is also stronger in preteens than in older individuals. This is a preventive measure, much like wearing a seatbelt—you put it on before you start driving, not after an accident.

​Catch-Up Vaccinations for Older Teens and Adults

​If someone misses the vaccination at the recommended age, catch-up vaccinations are advised. The vaccine is approved for everyone through age 26. For those aged 15 and older, the vaccination schedule involves three doses instead of two.

​HPV Vaccine Age Limit: It's Never Too Late?

​Recent FDA approval has expanded the use of Gardasil 9 to adults up to age 45. The decision for adults between 27 and 45 to get vaccinated should be made through a shared decision-making process with a healthcare provider. It may not be as beneficial for everyone in this age range, as many have already been exposed to HPV. However, for those in new monogamous relationships or who want to ensure protection against strains they haven't encountered, it can still be a valuable option.

Consult Top Specialists

Dr. Mohamed Azeem, General Physician/ Internal Medicine Specialist

Dr. Mohamed Azeem

General Physician/ Internal Medicine Specialist

2 Years • MBBS,MD(Internal Medicine) CCEBDM

Karaikudi

Apollo Hospitals Karaikudi, Karaikudi

450

450

No Booking Fees

Dr. Sandhya Chandel, General Physician/ Internal Medicine Specialist

Dr. Sandhya Chandel

General Physician/ Internal Medicine Specialist

16 Years • MBBS, MD (Int. Med.), IDCCM

Bilaspur

Apollo Hospitals Seepat Road, Bilaspur

recommendation

94%

(125+ Patients)

700

700

No Booking Fees

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

85%

(25+ Patients)

600

500

​The HPV Vaccine Schedule: Dosage and Timing

​Adhering to the correct schedule is vital for the vaccine's effectiveness.

​Schedule for Younger Adolescents (9-14 years)

  • ​Dose 1: Initial dose.
  • ​Dose 2: 6 to 12 months after the first dose.
  • ​(A 2-dose schedule is sufficient for strong immunity in this age group).

​Schedule for Older Recipients (15+ years) and Immunocompromised Individuals

  • ​Dose 1: Initial dose.
  • ​Dose 2: 1-2 months after the first dose.
  • ​Dose 3: 6 months after the first dose (at least 12 weeks after the second dose).

​Debunking Common Myths About the HPV Vaccine

Let's debunk some common myths about HPV vaccine:

​Myth vs. Fact: Safety and Side Effects

  • ​Myth: The vaccine is not safe and has severe long-term side effects.
  • ​Fact: The HPV vaccine has been extensively studied for over 15 years. Monitoring by organizations like the CDC and WHO consistently confirms its safety. Millions of doses have been administered globally with an excellent safety profile. Most side effects are mild and temporary.

​Addressing Concerns About Promiscuity and Early Vaccination

  • ​Myth: Vaccinating children will encourage earlier sexual activity.
  • ​Fact: Multiple studies have shown that receiving the HPV vaccine does not lead to an increase in sexual activity or risky sexual behavior among teens. The vaccine is about cancer prevention, not permission. It's a health decision, not a moral one.

​Potential Side Effects and Safety Profile

​Like any vaccine, the HPV vaccine can cause minor reactions, which are signs that the body is building protection. 
These typically resolve within a day or two and include:

  • ​Pain, redness, or swelling at the injection site.
  • ​Mild fever.
  • ​Headache or feeling tired.
  • ​Nausea.
  • ​Muscle or joint pain.

​Understanding the Data on Severe Reactions

​Severe allergic reactions (anaphylaxis) are extremely rare (estimated at about 1.8 per million doses) and occur within minutes of vaccination. This is why recipients are asked to wait for 15-30 minutes after the shot—to ensure immediate medical care is available if needed. There is no proven link between the HPV vaccine and chronic conditions like infertility or autoimmune diseases.

​Where to Get Vaccinated and How to Pay for It?

​The HPV vaccine is available at most pediatrician and family medicine offices, community health clinics, and 
pharmacies. Cost of hpv vaccine can vary. Many health insurance plans cover it fully for the recommended age groups. Government programs and manufacturer assistance programs may also help reduce costs. It's best to check with your provider and insurance company for specific details.

​Talking to Your Doctor About the HPV Vaccine

​Open a conversation with your healthcare provider. Come prepared with questions. A trusted doctor can provide 
personalized advice based on your or your child's health history and address any specific concerns you might have.

Consult Top Specialists

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

1000

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

​Conclusion

​The HPV vaccine represents one of the most significant advances in modern medicine for cancer prevention. It is a safe, effective, and powerful tool that protects against multiple types of cancer caused by the human papillomavirus. By vaccinating adolescents, we can create a generation with dramatically lower rates of cervical, throat, and other cancers. For adults who may have missed it earlier, it's still worth a conversation with a doctor. This decision isn't just about preventing an STI; it's about proactively safeguarding your long-term health and future. Don't let misinformation stand in the way of this life-saving prevention. Take the step to learn more and talk to a healthcare professional today.

 

Consult Top Specialists

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

600

Dr.sanchayan Mandal, Oncologist

Dr.sanchayan Mandal

Oncologist

17 Years • MBBS, DrNB( MEDICAL ONCOLOGY), DNB (RADIOTHERAPY),ECMO. PDCR. ASCO

Kolkata

Dr. Sanchayan Mandal Oncology Clinic, Kolkata

1500

1500

No Booking Fees

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

1000

No Booking Fees

Dr. Sanchayan Mandal, Oncologist

Dr. Sanchayan Mandal

Oncologist

17 Years • MBBS, DNB Raditherapy, DrNB Medical Oncology

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

1500

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

2000

No Booking Fees

Consult Top Specialists

Dr. Mohamed Azeem, General Physician/ Internal Medicine Specialist

Dr. Mohamed Azeem

General Physician/ Internal Medicine Specialist

2 Years • MBBS,MD(Internal Medicine) CCEBDM

Karaikudi

Apollo Hospitals Karaikudi, Karaikudi

450

450

No Booking Fees

Dr. Sandhya Chandel, General Physician/ Internal Medicine Specialist

Dr. Sandhya Chandel

General Physician/ Internal Medicine Specialist

16 Years • MBBS, MD (Int. Med.), IDCCM

Bilaspur

Apollo Hospitals Seepat Road, Bilaspur

recommendation

94%

(125+ Patients)

700

700

No Booking Fees

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Dr Aakash Andgi, General Physician/ Internal Medicine Specialist

Dr Aakash Andgi

General Physician/ Internal Medicine Specialist

9 Years • MBBS MD

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

600

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

85%

(25+ Patients)

600

500

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Frequently Asked Questions

​1. If I'm over 26, is the HPV vaccine worth it?

It can be. For adults aged 27 to 45, the decision should be made with a doctor. If you have new partners or haven't been exposed to all HPV strains the vaccine covers, it may still offer protection. A healthcare provider can help you weigh the benefits based on your personal history.

​2. Do I still need Pap smears if I've had the HPV vaccine?

Yes. The vaccine protects against the most common cancer-causing strains, but not all of them. Regular cervical cancer screening (Pap smears and/or HPV tests) remains an essential part of women's health care, as recommended by your doctor.

​3. Why should boys get the HPV vaccine?

The vaccine protects boys from HPV-related cancers, including cancers of the throat, penis, and anus. It also helps prevent the spread of HPV to their partners, contributing to community-wide immunity (herd immunity) and reducing overall cancer rates.

​4. How long does protection from the HPV vaccine last?

Research indicates that protection provided by the HPV vaccine is long-lasting. Data from follow-up studies show no evidence of waning protection for at least 10-15 years after vaccination. Ongoing monitoring continues to confirm its durability.

5. Can the HPV vaccine treat an existing HPV infection or genital warts?

No. The HPV vaccine is a preventive vaccine, not a treatment. It is designed to prevent new infections from the specific HPV types covered by the vaccine. It does not clear existing infections or treat related diseases.