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Safe Painkillers During Pregnancy Guidelines

Discover which painkillers are safe during pregnancy and which to avoid. Learn expert-approved guidelines, natural remedies, and when to consult a doctor for pain relief while expecting.

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Written by Dr. Dhankecha Mayank Dineshbhai

Reviewed by Dr. M L Ezhilarasan MBBS

Last updated on 11th Aug, 2025

Safe Painkillers During Pregnancy

Pregnancy is a beautiful journey, but it can also bring discomfort, aches, and pains. Whether it’s back pain, headaches, or muscle soreness, many expecting mothers wonder which painkillers are safe to take without harming their baby. It’s important to know that not all medications are safe during pregnancy, and some can pose serious risks.

In this article, we’ll guide you through safe pain relief options, what to avoid, and when to consult your doctor.

Understanding Pain During Pregnancy

Pregnancy causes many physical changes that can lead to discomfort, such as:

  • Hormonal shifts causing headaches
  • Weight gain leading to back and joint pain
  • Ligament stretching causing pelvic or abdominal discomfort

While some pain is normal, persistent or severe pain should always be discussed with a doctor.

Safe Painkillers During Pregnancy

Not all pain medications are safe for pregnant women. Here’s what experts generally recommend:

1. Paracetamol (Acetaminophen) – The Safest Option

  • Why it’s safe: Widely studied and considered the safest painkiller for short-term use in pregnancy.
    Used for: Headaches, mild fever, muscle aches, and general pain.
  • Dosage: Follow the recommended dose (usually 500-1000 mg per dose, not exceeding 4000 mg in 24 hours).
  • Precaution: Avoid long-term or excessive use unless prescribed by a doctor.

2. Topical Pain Relief (Gels & Creams)

  • Why it’s safe: Applied externally, so minimal absorption into the bloodstream.
  • Used for: Localised muscle or joint pain.
  • Example: Menthol-based creams (avoid high-dose salicylates unless approved by a doctor).

Consult Top Specialists

Dr. Vandana Sinha, Obstetrician and Gynaecologist

Dr. Vandana Sinha

Obstetrician and Gynaecologist

14 Years • MBBS, MS(Obs & Gyn), Fellow in Gynec-Onco. & Gynec Endoscopy

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

90%

(175+ Patients)

1000

1000

Dr. Jyoti Anant Bobe, Obstetrician and Gynaecologist

Dr. Jyoti Anant Bobe

Obstetrician and Gynaecologist

29 Years • MD. Obs & Gyn, MBBS

Mumbai

Apollo Hospitals CBD Belapur, Mumbai

recommendation

94%

(25+ Patients)

1700

1700

Dr. Swati Shah, Surgical Oncologist

Dr. Swati Shah

Surgical Oncologist

15 Years • DNB Surgical Oncology, certified Robotic Cancer Surgeon

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

91%

(25+ Patients)

1500

1600

Dr. Antharvedi Santhi, Obstetrician and Gynaecologist

Dr. Antharvedi Santhi

Obstetrician and Gynaecologist

15 Years • MBBS Ms(obstetrics and gynaecology)

Hyderguda

Apollo Hospitals Hyderguda, Hyderguda

600

600

Dr. Karuna Ratwani, Obstetrician and Gynaecologist

Dr. Karuna Ratwani

Obstetrician and Gynaecologist

11 Years • MBBS, MS( Obstetrics & Gynaecology), F.MAS, FICRS Advanced Diploma in Minimal Access surgery Fellow of International College of Robotic Surgeons Diploma in Reproductive Medicine, Kiel-Germany Masters in Cosmetic Gynaecology , Greifswald-Germany Masterclass in Obstetrics & Gynaecology Ultrasound ( ISUOG, UK)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

82%

(25+ Patients)

1500

1500

Avoid These Painkillers Unless Prescribed

Some painkillers can harm the baby, especially in certain trimesters:

NSAIDs (Ibuprofen, Aspirin, Naproxen):

  • Risk: Can affect fetal heart, kidneys, and cause complications in the third trimester.
  • Exception: Low-dose aspirin may be prescribed for specific conditions (only under doctor’s guidance).

Opioids (Codeine, Tramadol):

  • Risk: Can cause dependency in the baby and breathing problems.
  • Only use if prescribed for severe pain under strict medical supervision.

Natural & Non-Medical Ways to Manage Pain

Before reaching for medication, try these safer alternatives:

1. Warm Compress or Heating Pad

  • Helps relax muscles and relieve back pain.
  • Avoid very hot temperatures; warm, not scalding.

2. Prenatal Massage & Gentle Stretching

  • Reduces muscle tension and improves circulation.
  • Avoid deep tissue massage; opt for a certified prenatal masseuse.

3. Proper Posture & Support

  • Use a pregnancy pillow for better sleep posture.
  • Wear supportive shoes to reduce back strain.

4. Hydration & Balanced Diet

  • Dehydration can cause headaches—drink plenty of water.
  • Magnesium-rich foods (bananas, nuts) may help with muscle cramps.

5. Prenatal Yoga & Light Exercise

  • Strengthens muscles and improves flexibility.
  • Always consult your doctor before starting any new exercise.

When to See a Doctor

While mild pain is common, some symptoms need medical attention:

  • Severe or persistent headaches (could indicate high blood pressure).
  • Sharp abdominal pain (possible sign of complications).
  • Fever with pain (may indicate infection).
  • Swelling with pain (could signal blood clots or preeclampsia).

If over-the-counter pain relief isn’t helping, consult your doctor before trying stronger medications.

Final Tips for Safe Pain Relief

1. Always check with your doctor before taking any medication.
2. Stick to the lowest effective dose for the shortest time.
3. Avoid self-medicating; some drugs may seem harmless, but can be risky.
4. Keep a pain diary to track frequency and triggers.

Need Expert Advice?

If you’re unsure about which painkillers are safe for you, Apollo 24|7 offers expert consultations with obstetricians and gynaecologists. You can:

  • Book a video consultation
  • Schedule lab tests if needed
  • Get personalised medication guidance

Pregnancy is a delicate phase, and your safety and your baby’s come first. Always seek professional advice before taking any medication.

Conclusion

Managing pain during pregnancy requires extra caution, as not all medications are safe for your baby. Paracetamol is typically considered the safest option, while stronger painkillers should only be used under medical supervision. Always consult your doctor for guidance and explore natural pain relief methods to ensure a healthy, comfortable pregnancy.

Consult Top Specialists

Dr. Vandana Sinha, Obstetrician and Gynaecologist

Dr. Vandana Sinha

Obstetrician and Gynaecologist

14 Years • MBBS, MS(Obs & Gyn), Fellow in Gynec-Onco. & Gynec Endoscopy

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

90%

(175+ Patients)

1000

1000

Dr. Jyoti Anant Bobe, Obstetrician and Gynaecologist

Dr. Jyoti Anant Bobe

Obstetrician and Gynaecologist

29 Years • MD. Obs & Gyn, MBBS

Mumbai

Apollo Hospitals CBD Belapur, Mumbai

recommendation

94%

(25+ Patients)

1700

1700

Dr. Swati Shah, Surgical Oncologist

Dr. Swati Shah

Surgical Oncologist

15 Years • DNB Surgical Oncology, certified Robotic Cancer Surgeon

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

91%

(25+ Patients)

1500

1600

Dr. Antharvedi Santhi, Obstetrician and Gynaecologist

Dr. Antharvedi Santhi

Obstetrician and Gynaecologist

15 Years • MBBS Ms(obstetrics and gynaecology)

Hyderguda

Apollo Hospitals Hyderguda, Hyderguda

600

600

Dr. Karuna Ratwani, Obstetrician and Gynaecologist

Dr. Karuna Ratwani

Obstetrician and Gynaecologist

11 Years • MBBS, MS( Obstetrics & Gynaecology), F.MAS, FICRS Advanced Diploma in Minimal Access surgery Fellow of International College of Robotic Surgeons Diploma in Reproductive Medicine, Kiel-Germany Masters in Cosmetic Gynaecology , Greifswald-Germany Masterclass in Obstetrics & Gynaecology Ultrasound ( ISUOG, UK)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

82%

(25+ Patients)

1500

1500

Consult Top Specialists

Dr. Vandana Sinha, Obstetrician and Gynaecologist

Dr. Vandana Sinha

Obstetrician and Gynaecologist

14 Years • MBBS, MS(Obs & Gyn), Fellow in Gynec-Onco. & Gynec Endoscopy

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

90%

(175+ Patients)

1000

1000

Dr. Jyoti Anant Bobe, Obstetrician and Gynaecologist

Dr. Jyoti Anant Bobe

Obstetrician and Gynaecologist

29 Years • MD. Obs & Gyn, MBBS

Mumbai

Apollo Hospitals CBD Belapur, Mumbai

recommendation

94%

(25+ Patients)

1700

1700

Dr. Swati Shah, Surgical Oncologist

Dr. Swati Shah

Surgical Oncologist

15 Years • DNB Surgical Oncology, certified Robotic Cancer Surgeon

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

91%

(25+ Patients)

1500

1600

Dr. Antharvedi Santhi, Obstetrician and Gynaecologist

Dr. Antharvedi Santhi

Obstetrician and Gynaecologist

15 Years • MBBS Ms(obstetrics and gynaecology)

Hyderguda

Apollo Hospitals Hyderguda, Hyderguda

600

600

Dr. Karuna Ratwani, Obstetrician and Gynaecologist

Dr. Karuna Ratwani

Obstetrician and Gynaecologist

11 Years • MBBS, MS( Obstetrics & Gynaecology), F.MAS, FICRS Advanced Diploma in Minimal Access surgery Fellow of International College of Robotic Surgeons Diploma in Reproductive Medicine, Kiel-Germany Masters in Cosmetic Gynaecology , Greifswald-Germany Masterclass in Obstetrics & Gynaecology Ultrasound ( ISUOG, UK)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

82%

(25+ Patients)

1500

1500

Consult Top Specialists

Dr. Vandana Sinha, Obstetrician and Gynaecologist

Dr. Vandana Sinha

Obstetrician and Gynaecologist

14 Years • MBBS, MS(Obs & Gyn), Fellow in Gynec-Onco. & Gynec Endoscopy

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

90%

(175+ Patients)

1000

1000

Dr. Jyoti Anant Bobe, Obstetrician and Gynaecologist

Dr. Jyoti Anant Bobe

Obstetrician and Gynaecologist

29 Years • MD. Obs & Gyn, MBBS

Mumbai

Apollo Hospitals CBD Belapur, Mumbai

recommendation

94%

(25+ Patients)

1700

1700

Dr. Swati Shah, Surgical Oncologist

Dr. Swati Shah

Surgical Oncologist

15 Years • DNB Surgical Oncology, certified Robotic Cancer Surgeon

Ahmedabad

Apollo Hospitals Gandhinagar, Ahmedabad

recommendation

91%

(25+ Patients)

1500

1600

Dr. Antharvedi Santhi, Obstetrician and Gynaecologist

Dr. Antharvedi Santhi

Obstetrician and Gynaecologist

15 Years • MBBS Ms(obstetrics and gynaecology)

Hyderguda

Apollo Hospitals Hyderguda, Hyderguda

600

600

Dr. Karuna Ratwani, Obstetrician and Gynaecologist

Dr. Karuna Ratwani

Obstetrician and Gynaecologist

11 Years • MBBS, MS( Obstetrics & Gynaecology), F.MAS, FICRS Advanced Diploma in Minimal Access surgery Fellow of International College of Robotic Surgeons Diploma in Reproductive Medicine, Kiel-Germany Masters in Cosmetic Gynaecology , Greifswald-Germany Masterclass in Obstetrics & Gynaecology Ultrasound ( ISUOG, UK)

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

82%

(25+ Patients)

1500

1500

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