apollo

What Leads To Signs Of Blood Clot ?

Learn about the causes and symptoms of blood clots. This guide explains what a blood clot is, how it forms, and the key signs to watch for in your legs, arms, and lungs. Stay informed and know when to seek medical help.

reviewerImg

Written by Dr. J T Hema Pratima

Reviewed by Dr. Md Yusuf Shareef MBBS

Last updated on 12th Sep, 2025

blood clot

Introduction

A blood clot’s primary function is to stop bleeding—a vital process that saves your life after a cut. However, when a clot forms unnecessarily inside a vein or artery, it can become a dangerous medical emergency. Understanding what leads to the signs of a blood clot is crucial for your health. These clots can break loose and travel to your lungs, heart, or brain, causing life-threatening conditions like a pulmonary embolism, heart attack, or stroke. This article will guide you through the unmistakable symptoms, the underlying causes, and the key risk factors you need to be aware of. By recognizing the early warning signs, you can take prompt action and seek the medical attention that could save your life.

What is a Blood Clot, Exactly?

A blood clot, or thrombus, is a gellike mass formed by platelets and fibrin in the blood to repair damaged blood vessels. Think of it as your body’s natural plug for a leak.

The Lifesaving vs. LifeThreatening Balance

This clotting mechanism (coagulation) is essential. Without it, a simple scrape could lead to uncontrolled bleeding. The problem arises when this process is triggered internally without an obvious injury. A clot that forms and stays in a deep vein (often in the leg) is called a Deep Vein Thrombosis (DVT). If a piece of that clot breaks off and travels through the bloodstream, it becomes an embolus. This embolus can lodge itself in a critical artery, blocking blood flow to essential organs—this is an embolism, and it’s a medical catastrophe.

Recognizing the Signs: Symptoms by Location

The symptoms of a blood clot are entirely dependent on where it is located. Recognizing these signs is the first step toward getting help.

Deep Vein Thrombosis (DVT) in Legs or Arms

This is one of the most common types of clots. Signs include:

  • Swelling in one limb (foot, ankle, or leg).
  • Pain or tenderness, often described as a cramping or soreness, that starts in the calf.
  • Skin that is warm to the touch over the affected area.
  • Red or discolored skin.
  • A feeling of heaviness or aching.
     

Pulmonary Embolism (PE) in the Lungs

A PE occurs when a DVT clot breaks free and lodges in the lungs. This is life threatening and symptoms appear suddenly:

  • Sudden shortness of breath.
  • Sharp, stabbing chest pain that may worsen with a deep breath or coughing.
  • Rapid heart rate.
  • Coughing, sometimes with bloody mucus.
  • Feeling lightheaded, dizzy, or fainting.
     

Clots in the Heart (Heart Attack)

A clot in a coronary artery can cause a heart attack. Symptoms include:

  • Chest pain or pressure (angina).
  • Pain radiating to the jaw, neck, shoulder, or arm.
  • Shortness of breath.
  • Cold sweat, nausea, or lightheadedness.
     

Clots in the Brain (Stroke)

A clot blocking blood flow to the brain causes an ischemic stroke. Remember the acronym FAST:

  • Face drooping.
  • Arm weakness.
  • Speech difficulty.
  • Time to call emergency services.
     

Clots in the Abdomen (Mesenteric Ischemia)

Though rarer, abdominal clots cause severe:

  • Abdominal pain, often after eating.
  • Nausea, vomiting, and diarrhea.
  • Bloating and bloody stools.

Consult a General Physician for the best advice

Dr. Anand Ravi, General Physician

Dr. Anand Ravi

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

IMAGE
Dr. D Bhanu Prakash, General Practitioner

Dr. D Bhanu Prakash

General Practitioner

10 Years • MBBS, AFIH, Advanced certificate in critical care medicine, Fellowship in critical care medicine

Hyderabad

Apollo 24|7 Clinic, Hyderabad

690

Dr. Mohamed Azeem, General Physician/ Internal Medicine Specialist

Dr. Mohamed Azeem

General Physician/ Internal Medicine Specialist

2 Years • MBBS,MD(Internal Medicine) CCEBDM

Karaikudi

Apollo Hospitals Karaikudi, Karaikudi

450

450

No Booking Fees

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

85%

(25+ Patients)

600

500

The Root Causes: What Leads to Dangerous Blood Clots

Doctors use a model called Virchow’s Triad to explain the three primary causes of thrombosis.

Venous Stasis (When Blood Slows Down)

When blood flow slows or becomes sluggish, it gives platelets a chance to cluster and form a clot. This is a major reason why blood clots are a risk after long periods of immobility, such as:

  • Extended bed rest after surgery or illness.
  • Longhaul flights or car rides (>4 hours).
  • Paralysis.
     

Hypercoagulability (When Blood Clots Too Easily)

This refers to an increased tendency for blood to clot. It can be:

  • Genetic: Conditions like Factor V Leiden mutation or Prothrombin gene mutation.
  • Acquired: Cancer, autoimmune diseases (lupus), pregnancy, hormone replacement therapy or birth control pills, smoking, and obesity.
     

Endothelial Injury (When Vessel Walls are Damaged)

The inner lining of a blood vessel is called the endothelium. If it’s damaged, it provides a rough surface for a clot to begin forming. Causes include:

  • Major surgery or physical trauma (e.g., a broken bone).
  • Catheters or central lines.
  • Inflammation from infection or vasculitis.

Key Risk Factors You Need to Know

Certain conditions and lifestyles significantly increase your risk.

Medical Conditions and Procedures

  • Cancer and its treatments.
  • Heart disease (heart failure, atrial fibrillation).
  • Recent major surgery (especially hip or knee replacement).
  • COVID19 infection (increases inflammation and clotting risk).
  • Previous history of DVT or PE.
  • Pregnancy and the postpartum period (due to hormonal changes and pressure on veins).
     

Lifestyle and Environmental Factors

  • Smoking (damages blood vessels).
  • Obesity (increases pressure in veins).
  • Prolonged immobility (sitting or bed rest).
  • Dehydration (makes blood thicker).
     

Genetic and Uncontrollable Factors

  • Family history of blood clots.
  • Age (risk increases over 60).
  • Inherited clotting disorders.

How Are Blood Clots Diagnosed?

If a blood clot is suspected, doctors use several tools:

  • Ultrasound: The primary test for DVT, using sound waves to visualize blood flow in the veins.
  • Dimer Blood Test: Measures a substance released when a clot breaks up. A negative result often rules out a major clot.
  • CT Scan or MRI: Used to visualize clots in the lungs (CT pulmonary angiogram) or other organs.
  • Venography: An Xray of veins using a special dye.

If you are experiencing any concerning symptoms, it is crucial to get evaluated. You can consult a doctor online with Apollo24|7 for an initial assessment, who can advise if further in person diagnostics are needed.

Preventing Blood Clots: Proactive Steps You Can Take

You can mitigate your risk through simple, effective habits:

  • Move Regularly: On long trips, get up, walk, and stretch your legs every 12 hours. Flex your ankles while seated.
  • Stay Hydrated: Drink plenty of water to avoid thickening of the blood.
  • Exercise and Maintain a Healthy Weight.
  • Wear Compression Stockings: Especially if you have a high risk or are recovering from surgery.
  • Follow Medical Advice: If you are at high risk, your doctor may prescribe blood thinners (anticoagulants) prophylactically.

Quick Takeaways: Key Points on Blood Clots

  • Clots are vital for healing but dangerous when they form internally.
  • DVT symptoms include swelling, pain, warmth, and redness in one limb.
  • PE symptoms are sudden: shortness of breath, chest pain, and coughing.
  • The three main causes are slow blood flow, "sticky" blood, and vessel damage.
  • Major risk factors include surgery, cancer, immobility, smoking, and genetics.
  • Seek immediate emergency care for signs of PE, heart attack, or stroke.
  • Prevention is key: move often, stay hydrated, and manage risk factors.

Conclusion

Understanding what leads to the signs of a blood clot empowers you to protect your health. While some risk factors are beyond our control, many lifestyle choices—like staying active, hydrated, and avoiding smoking—can significantly reduce your risk. The most important takeaway is to listen to your body. The symptoms of a DVT or PE are distinct and should never be ignored. Prompt medical attention is not just advisable; it is imperative. If you have persistent concerns about your personal risk factors, especially with a family history or ahead of a major surgery, have a conversation with your doctor. If your condition does not improve after trying these methods, book a physical visit to a doctor with Apollo24|7 for a comprehensive evaluation and personalized prevention plan. Your vigilance could be lifesaving.

Consult a General Physician for the best advice

Dr. Anand Ravi, General Physician

Dr. Anand Ravi

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

IMAGE
Dr. D Bhanu Prakash, General Practitioner

Dr. D Bhanu Prakash

General Practitioner

10 Years • MBBS, AFIH, Advanced certificate in critical care medicine, Fellowship in critical care medicine

Hyderabad

Apollo 24|7 Clinic, Hyderabad

690

Dr. Mohamed Azeem, General Physician/ Internal Medicine Specialist

Dr. Mohamed Azeem

General Physician/ Internal Medicine Specialist

2 Years • MBBS,MD(Internal Medicine) CCEBDM

Karaikudi

Apollo Hospitals Karaikudi, Karaikudi

450

450

No Booking Fees

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

85%

(25+ Patients)

600

500


 

Consult a General Physician for the best advice

Dr. Anand Ravi, General Physician

Dr. Anand Ravi

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

IMAGE
Dr. D Bhanu Prakash, General Practitioner

Dr. D Bhanu Prakash

General Practitioner

10 Years • MBBS, AFIH, Advanced certificate in critical care medicine, Fellowship in critical care medicine

Hyderabad

Apollo 24|7 Clinic, Hyderabad

690

Dr. Mohamed Azeem, General Physician/ Internal Medicine Specialist

Dr. Mohamed Azeem

General Physician/ Internal Medicine Specialist

2 Years • MBBS,MD(Internal Medicine) CCEBDM

Karaikudi

Apollo Hospitals Karaikudi, Karaikudi

450

450

No Booking Fees

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

85%

(25+ Patients)

600

500

Consult a General Physician for the best advice

Dr. Anand Ravi, General Physician

Dr. Anand Ravi

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

IMAGE
Dr. D Bhanu Prakash, General Practitioner

Dr. D Bhanu Prakash

General Practitioner

10 Years • MBBS, AFIH, Advanced certificate in critical care medicine, Fellowship in critical care medicine

Hyderabad

Apollo 24|7 Clinic, Hyderabad

690

Dr. Mohamed Azeem, General Physician/ Internal Medicine Specialist

Dr. Mohamed Azeem

General Physician/ Internal Medicine Specialist

2 Years • MBBS,MD(Internal Medicine) CCEBDM

Karaikudi

Apollo Hospitals Karaikudi, Karaikudi

450

450

No Booking Fees

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

85%

(25+ Patients)

600

500

More articles from Stroke

Frequently Asked Questions

Can you have a blood clot without any obvious symptoms?

Yes, it is possible, especially with smaller DVTs. Some clots are only discovered when they cause a more serious complication like a PE. This is why managing risk factors is so important.
 

How long after surgery are you at risk for blood clots?

The highest risk period is typically within the first 12 weeks after surgery, but the elevated risk can continue for up to 3 months, especially after major orthopedic procedures.
 

Are the symptoms of a blood clot in the leg always severe?

No. The symptoms of a blood clot in the leg can be mild, like a persistent, dull ache or slight swelling that feels like a pulled muscle. Any new, unexplained symptom in one limb should be checked.
 

Can dehydration really cause a blood clot?

Yes. Severe dehydration can make your blood thicker and more viscous, which increases the chances of platelets clumping together and forming a clot.
 

What is the difference between a blood clot and a bruise?

A bruise is bleeding under the skin from damaged capillaries, causing discoloration. A blood clot (DVT) occurs deep within a vein, causing swelling, pain, and warmth that won't go away like a bruise does.