Weight Gain, Mood Swings? TSH Test Guidance for Indian Men Over 50
Experiencing weight gain, fatigue, or mood swings? A TSH test can help Indian men over 50 detect thyroid imbalances early. Learn when to test, what results mean, and next steps.

Written by Dr. Shaik Abdul Kalam
Reviewed by Dr. Rohinipriyanka Pondugula MBBS
Last updated on 6th Aug, 2025

As men in India cross the age of 50, they often experience various changes in their bodies and daily lives. While some of these changes are a natural part of getting older, certain health conditions can emerge or become more noticeable. One such condition that is frequently overlooked in older men is related to thyroid health. The thyroid gland, a small, butterfly-shaped organ located at the base of your neck, plays a vital role in controlling your body's metabolism, energy levels, heart rate, and even your mood and thinking.
For men over 50, understanding the role of their thyroid and the importance of a simple blood test, the Thyroid-Stimulating Hormone (TSH) test, is crucial. Symptoms like unexplained weight gain or sudden mood swings might not just be signs of ageing; they could point to an underlying thyroid imbalance that needs attention.
Why Thyroid Symptoms Are Often Missed in Older Men?
Thyroid disorders, particularly an underactive thyroid (hypothyroidism), can affect men too, although they are more commonly associated with women. In older men, diagnosing thyroid problems can be tricky because the symptoms are often subtle, not specific, and can easily be confused with other common conditions that come with age.
Here are some reasons why thyroid symptoms might be missed in men over 50:
- Vague Symptoms: Symptoms like fatigue, weight changes, and mood swings are common complaints in older adults and are often put down to stress, lifestyle, or simply getting older. This can lead doctors and patients to overlook the thyroid as a possible cause.
- Less Awareness: There is generally less awareness about thyroid issues in men compared to women, leading to less frequent screening or consideration of thyroid problems during routine check-ups.
- Overlap with Other Conditions: Symptoms like erectile dysfunction, changes in libido, or male breast enlargement can be linked to thyroid dysfunction but might also be caused by other health issues common in older men, such as obesity or diabetes. This overlap can make diagnosis difficult.
- "Apathetic Hyperthyroidism": In some older men, an overactive thyroid (hyperthyroidism) might present with less obvious, "apathetic" symptoms like general weakness, weight loss, and depression, rather than the classic signs of nervousness or a racing heart seen in younger individuals.
Without regular checks, these thyroid issues can go undiagnosed for a long time, quietly affecting important body systems and potentially making existing health problems worse or leading to new ones. The TSH test acts as a vital early warning system, prompting further investigation and timely help.
How the TSH Test Works?
The Thyroid-Stimulating Hormone (TSH) test is the main and most sensitive blood test used to check how your thyroid is working. TSH is made by the pituitary gland, a small gland at the base of your brain. Its job is to tell your thyroid gland how much thyroid hormone to make.
Here is how it works:
- When thyroid hormone levels are low: The pituitary gland senses this and releases more TSH. This makes the thyroid produce more hormones. This means you will have a high TSH level in your blood, which points to an underactive thyroid (hypothyroidism).
- When thyroid hormone levels are high: The pituitary gland responds by releasing less TSH. It tries to slow down thyroid hormone production. This leads to a low TSH level in your blood, which points to an overactive thyroid (hyperthyroidism).
- So, the TSH test indirectly but very effectively shows how well your thyroid gland is working. It is often the first step in finding out if you have either an underactive or overactive thyroid.
Common Thyroid Symptoms in Men Over 50
While thyroid symptoms can be subtle, it's important for men over 50 to be aware of the signs that might suggest a thyroid imbalance. Recognising these can prompt a discussion with your doctor and lead to early diagnosis.
Symptoms of an Underactive Thyroid (Hypothyroidism):
- Unexplained Weight Gain: This is a very common symptom, as a slow metabolism makes it harder to burn calories.
- Persistent Fatigue and Low Energy: Feeling unusually tired, even after enough rest, is a key indicator.
- Mood Swings, Depression, or Irritability: Thyroid hormones affect brain chemistry, and an imbalance can lead to changes in mood.
- Feeling Cold Easily: You might feel colder than others, even in a warm room.
- Constipation: A slower metabolism can affect bowel movements.
- Dry Skin and Hair Loss: Skin can become dry and flaky, and hair might thin or become brittle.
- Muscle Aches, Weakness, or Stiffness: Generalised body aches and muscle weakness can occur.
- Memory Problems or Difficulty Concentrating: Often described as "brain fog," this can impact daily activities.
- Decreased Libido (Sex Drive): Thyroid hormones influence sex hormone levels.
- Erectile Dysfunction: This can be a symptom, though it has many other causes.
Symptoms of an Overactive Thyroid (Hyperthyroidism):
- Unexplained Weight Loss: Despite eating normally or even more, you might lose weight.
- Nervousness, Anxiety, or Irritability: Feeling restless or agitated.
- Rapid or Irregular Heartbeat: Palpitations or a racing heart.
- Increased Sweating and Heat Intolerance: Feeling hot even when others are comfortable.
- Tremors: A slight trembling in your hands.
- Difficulty Sleeping: Insomnia or restless sleep.
- Increased Bowel Movements: More frequent trips to the toilet.
- Muscle Weakness: Particularly in the upper arms and thighs.
If you experience any of these symptoms, especially if they are new or persistent, it is important to talk to your doctor and consider a TSH test.
When to Get Your Thyroid Tested?
Given that thyroid problems can have subtle symptoms in older men and can significantly impact their health, regular TSH screening is advised. Many doctors suggest a baseline TSH test around age 50, followed by periodic checks every 1-2 years, or more often if symptoms appear or there is a family history of thyroid disorders.
It is especially important to ask for a TSH test if you experience any of the symptoms mentioned above, even if they seem mild or you think they are just part of getting older. Early detection allows for timely treatment and can prevent more serious health problems.
Testing Options for Men Over 50: Apollo 24|7 Packages
While the TSH Test for men over 50 is a great first step, sometimes your doctor might suggest more tests to get a complete picture of your thyroid health, especially if your TSH levels are not normal. Apollo 24|7 offers various thyroid tests for men 50 plus:
- Apollo Thyroid Assessment – Basic: Covers TSH, T3, T4, and CBC for initial screening.
- Free and Total Thyroid Profile: Measures total and free T3/T4 plus TSH for a complete thyroid overview.
- Apollo Thyroid Assessment – Advance: Includes TSH, full thyroid panel, thyroid antibodies (like Anti-TPO and Anti-Thyroglobulin Antibodies), CBC, and Vitamin D.
- Senior Citizen Health Check Essential: Offers TSH and general health screenings for older adults.
- Xpert Health Senior Citizen – Male: A comprehensive package with full thyroid profile and men’s wellness tests.
Get Your Health Assessed Here
Conclusion
As men in India cross the age of 50, paying attention to thyroid health becomes essential. Common issues like weight gain, fatigue, or mood changes are often mistaken for normal ageing, but they may be signs of thyroid imbalance. Scheduling a TSH test for men over 50 is a reliable way to assess thyroid function and detect problems early.
For a more complete evaluation, a thyroid test for men 50 plus, such as TSH, T3, and T4 levels, can offer deeper insights into hormone balance and overall well-being. With convenient and trusted services like Apollo 24|7, older men can take a proactive step toward improving energy, mood, heart health, and mental clarity.
Consult your doctor about making thyroid testing a routine part of your check-up. It is a simple measure with significant benefits for healthy ageing.
Get Your Health Assessed Here
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