I have never had sexual activity. Recently, during treatment for an anal fissure, I got a blood test. The results were: VDRL: Reactive TPHA: 10 (Negative) TPAB: 0.18 (Negative) I have no symptoms apart from the anal fissure, which is now cured. I am worried about these results. Could you please suggest what my next steps should be?

Answered by 1 Apollo Doctors

Dr Shaik Kalam

General Practitioner

MD (Physician)
3+ Yrs

Consult Now

A reactive VDRL with negative TPHA and TPAB usually indicates a false positive. Since you have no sexual history or symptoms, iti s likely non syphilitic. Still, consult a doctor to confirm.

Dr. Shaik Suggests...

Take a TPHA Test (Treponema Pallidium Hemagglutination Assay) Test or Take a RPR TEST FOR SYPHILIS Test

Book TPHA Test (Treponema Pallidium Hemagglutination Assay) Test Book RPR TEST FOR SYPHILIS Test

Answered 11/09/2025

More TPHA Test (Treponema Pallidium Hemagglutination Assay) Health Queries

View all

My blood report shows TPHA positive. Please suggest the treatment or medicine for this condition. It is urgent because I need to travel to Saudi Arabia soon

Answered by Apollo Doctors

My report shows syphilis is reactive with a 1:4 titre. I was told by a doctor at a clinic that penicillin injection is needed for treatment but it is rarely available. What should I do now and where can I get the injection. I am from Bangalore and would appreciate your advice.

Answered by Apollo Doctors

Hi. My VDRL is positive and TPHA is 1.0 negative. In October, my report showed this. The doctor gave 4 injections of 1.2 lakh each over 2 weeks. Before 2008, my VDRL was active and TPHA was not active. The doctor gave 2 injections of 2.4 lakh. From 2008 to August 2017, I did not have any ulcers. In 2017, one night I slept and in the morning I noticed a black spot on the shaft of my penis. The next day an ulcer appeared on the skin and after 4 days it went away, but the skin color did not return to normal. Recently, I have much itching and burning. Please help. I am currently in KSA.

Answered by Apollo Doctors

Disclaimer: Answers on Apollo 247 are not intended to replace your doctor advice. Always seek help of a professional doctor in case of an medical emergency or ailment.