Beta - 2 - Glycoprotein-1 IgG, IgM, IgA

Improper clotting of blood in your body can result from many factors. To determine the cause of such conditions, doctors can recommend a Beta-2 Glycoprotein 1 IgG/IgM test.

Beta-2 glycoprotein is an autoantibody that is associated with blood clotting disorders. This antibody detection test is also helpful in diagnosing the root cause of recurrent miscarriages and Antiphospholipid Syndrome (APS).

The Beta-2 Glycoprotein 1 IgG/IgM Test

Your body contains antibodies like IgG, IgM, and IgA. These antibodies fight foreign infections. In case of inappropriate blood clot formation, your body emits beta-2 glycoprotein that targets the lipid proteins. 

To counter the effect of beta-2 glycoprotein, immunoglobulins like IgG, IgA, and IgM become active. This test determines the presence of these three antibodies.

Here are the three tests that fall under the Beta-2 Glycoprotein 1 IgG/IgM test package:

• IgA: The medical experts determine the presence of immunoglobulin A. This antibody is the first course of defense against possible infections.
• IgG: This antibody is the most common type of antibody that circulates in your blood. The test detects its presence in your bloodstream.
• IgM: It is the first antibody secreted in response to foreign antigens. Similar to the above two antibodies, the Beta-2 Glycoprotein 1 IgG/IgM test evaluates its presence in your system.

If the antibodies test positive, there might be the presence of APS in your body. Cumulatively, experts determine the activeness of beta-2 glycoproteins through a blood sample. You do not need any special medical preparation for undergoing this test.

Why Should You Get Tested?

If you have blood clotting symptoms, your doctor may advise this Beta-2 Glycoprotein 1 IgG/IgM test. Some common symptoms include chest pain, shortness of breath, seizures, headaches, etc. This test detects one or more types (IgG, IgM, or IgA) of beta-2 glycoprotein 1 antibodies. Evaluating the presence of beta-2 glycoproteins can effectively treat several diseases. 

Medically reviewed by Dr. Jasmin Rath, Obstetrics & Gynaecology from apollo Hospitals Jubilee Hills, Hyderabad.