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Beta - 2 - Glycoprotein-1 IgG, IgM, IgA

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    Age group

    Above 10 years

    Improper clotting of blood in your body can result from many factors. To determine the cause of such conditions, doctors can recommend a Beta-2 Glycoprotein 1 IgG/IgM test.

    Beta-2 glycoprotein is an autoantibody that is associated with blood clotting disorders. This antibody detection test is also helpful in diagnosing the root cause of recurrent miscarriages and Antiphospholipid Syndrome (APS).

    The Beta-2 Glycoprotein 1 IgG/IgM Test

    Your body contains antibodies like IgG, IgM, and IgA. These antibodies fight foreign infections. In case of inappropriate blood clot formation, your body emits beta-2 glycoprotein that targets the lipid proteins. 

    To counter the effect of beta-2 glycoprotein, immunoglobulins like IgG, IgA, and IgM become active. This test determines the presence of these three antibodies.

    Here are the three tests that fall under the Beta-2 Glycoprotein 1 IgG/IgM test package:

    • IgA: The medical experts determine the presence of immunoglobulin A. This antibody is the first course of defense against possible infections.
    • IgG: This antibody is the most common type of antibody that circulates in your blood. The test detects its presence in your bloodstream.
    • IgM: It is the first antibody secreted in response to foreign antigens. Similar to the above two antibodies, the Beta-2 Glycoprotein 1 IgG/IgM test evaluates its presence in your system.

    If the antibodies test positive, there might be the presence of APS in your body. Cumulatively, experts determine the activeness of beta-2 glycoproteins through a blood sample. You do not need any special medical preparation for undergoing this test.

    Why Should You Get Tested?

    If you have blood clotting symptoms, your doctor may advise this Beta-2 Glycoprotein 1 IgG/IgM test. Some common symptoms include chest pain, shortness of breath, seizures, headaches, etc. This test detects one or more types (IgG, IgM, or IgA) of beta-2 glycoprotein 1 antibodies. Evaluating the presence of beta-2 glycoproteins can effectively treat several diseases. 

    Medically reviewed by Dr. Jasmin Rath, Obstetrics & Gynaecology from apollo Hospitals Jubilee Hills, Hyderabad.

    faqFrequently Asked Questions (FAQs)

    Frequently asked questions

    Antiphospholipid syndrome, better known as APS, is a condition with multiple blood clots in the arteries, veins and organs. It may even cause miscarriages in women if left unchecked. The beta-2-glycoprotein 1 IgG & IgM test is utilized to detect this ailment by measuring the number of corresponding antibodies in a blood sample.
    Usually seen in women, the antiphospholipid syndrome is commonly associated with the formation of intrusive blood clots. Some of the other symptoms of this condition include: Low blood platelet levels Anaemia The formation of reddish or purplish patterns on the skin Heart valve abnormalities Low blood platelet levels The formation of blood clots can also lead to multiple issues, such as: Chest pain and difficulty breathing Redness and swelling in the arm or leg, along with constant pain Frequent headaches Discomfort  Pain in the abdomen
    Antiphospholipid syndrome is an autoimmune disorder that occurs when the body’s immune system accidentally attacks the phospholipid-binding proteins in the cells by creating antibodies. It is mainly credited to genetic and environmental factors. The beta-2-glycoprotein-1 IgG & IgM test is used to detect this condition and prepare a treatment plan.
    The beta-2-glycoprotein-1 IgG and IgM test is a blood test used to detect the presence of IgG and IgM antibodies that may indicate a past or present case of antiphospholipid syndrome. It involves standard blood work that tests the blood sample against potential allergens that may form specific antibodies. If IgG/IgM antibodies are present, it is highly likely that the patient is suffering from APS.

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    The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results

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