I'm 32 weeks pregnant and I've been having this annoying itching on my hands and legs, but only at night. It's really bothering me. I got my liver function test done and it seems like my SGPT and SGOT levels, along with AP, are higher than normal. Everything else looks okay though. I've attached the report. Is there a chance I've got cholestasis or is there any risk I should be worried about with these results?

Dr Ibrahim Salah

General Practitioner

• MBBS
• 2+ Yrs

Consult Now

Based on your symptoms of itching in the hands and legs at night, along with high levels of SGPT, SGOT, and AP in your liver function tests, there is a possibility of cholestasis. Cholestasis is a condition where the normal flow of bile from the liver is impaired, leading to a buildup of bile acids in the body which can cause itching. To manage cholestasis during pregnancy, you can take Ursodeoxycholic acid (UDCA) at a dosage of 300mg to 600mg per day. UDCA helps to improve liver function and reduce itching in cholestasis. Additionally, you may also be prescribed antihistamines like Chlorpheniramine to help with the itching. It is important to follow up with your obstetrician for further evaluation and management of your condition. Regular monitoring of your liver function tests and close observation of your baby's well-being may be necessary to ensure a safe pregnancy outcome.

Answered 04/07/2025