I'm considering using an adapalene microsphere plus clindamycin phosphate gel that contains 0.1% adapalene and clindamycin phosphate equivalent to clindamycin 1%. I'm curious if it's a powerful retinol and exfoliant. Can I safely layer it with a mild AHA product, considering I have dry skin? If it's possible to layer without too much exfoliation, what AHA percentage would you suggest, and what type would be best?

Dr Chandra P

General Practitioner

• MBBS
• 5+ Yrs

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Adapalene Microsphere Plus Clindamycin Phosphate Gel is indeed a powerful retinol and exfoliant, containing 0.1% adapalene and 1% clindamycin phosphate. Adapalene helps control excess sebum production, removes dead skin cells, and opens pores, while clindamycin kills bacteria that cause acne.

For dry skin, it's essential to be cautious when layering retinoids with alpha-hydroxy acids (AHAs). Start by applying a small amount of the gel and gradually increase as your skin becomes more tolerant.

If you still want to layer it with a mild AHA product, consider the following:

AHA Options

1. Glycolic Acid (5-7%): A gentle, water-soluble AHA that helps brighten and exfoliate the skin.
2. Lactic Acid (5-10%): A hydrating AHA that exfoliates and helps retain moisture.

Tips for Layering

1. Apply the AHA product first, allowing it to absorb fully.
2. Wait a few minutes before applying the Adapalene Microsphere Plus Clindamycin Phosphate Gel.
3. Start with a low concentration of AHA and gradually increase as your skin becomes more tolerant.

Answered 04/07/2025