My sister is 33 years old. For the last few years, she has been experiencing joint pain and weight loss. We did a blood test and RA factor is negative. Please suggest what we can do for this?

Answered by 1 Apollo Doctors

Dr Kamran Mohammed

General Practitioner

MBBS
FIDM
5+ Yrs

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Even with negative RA factor, autoimmune arthritis is possible. Consider ANA and anti CCP testing. Weight loss should also be evaluated with basic blood work and possibly imaging.

Dr. Kamran Suggests...

Take a ANTI NUCLEAR ANTIBODY (ANA) Test or Take a Anti CCP Test (Cyclic Citrullinated Peptide) Test

Book ANTI NUCLEAR ANTIBODY (ANA) Test Book Anti CCP Test (Cyclic Citrullinated Peptide) Test

Answered 12/09/2025

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