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Blood Tests for Breast Cancer Detection

Know about the blood tests for breast cancer detection,who should get it done, symptoms and procedure for blood tests.

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Written by Dr. Siri Nallapu

Reviewed by Dr. J T Hema Pratima MBBS

Last updated on 4th Aug, 2025

Introduction 

Breast cancer is one of the most common cancers affecting women worldwide. Early detection plays a crucial role in successful treatment and recovery. While mammograms and biopsies are well-known diagnostic tools, blood tests are emerging as a promising method for detecting breast cancer early.

If you or a loved one is concerned about breast cancer, understanding how blood tests work and their role in diagnosis can be empowering. This article explains everything you need to know in simple, compassionate terms.

What Are Blood Tests for Breast Cancer?

Blood tests for breast cancer look for specific biomarkers—substances in the blood that may indicate the presence of cancer. These tests are not yet a replacement for mammograms or biopsies, but can provide additional information to help doctors:

  1. Detect early signs of cancer

  2. Monitor treatment progress

  3. Check for cancer recurrence

Consult a Top oncologist for advice

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Devashish Tripathi, Radiation Specialist Oncologist

Dr Devashish Tripathi

Radiation Specialist Oncologist

20 Years • MBBS, PLAB, MRCP (UK)- General Medicine, FRCR (Oncology), Certificate of Completion of Training (CCT)- Clinical Oncology

Delhi

Apollo Hospitals Indraprastha, Delhi

1500

150 Cashback

1500

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

89%

(25+ Patients)

1000

100 Cashback

2000

No Booking Fees

Dr. Sandeep Muzumder, Radiation Specialist Oncologist

Dr. Sandeep Muzumder

Radiation Specialist Oncologist

21 Years • MBBS (JIPMER, Pondicherry), MD (AIIMS, New Delhi)

Bhubaneswar

Apollo Hospitals Old Sainik School Road, Bhubaneswar

800

1000

No Booking Fees

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

4 Years • MBBS MD(RADIO THERAPY)

Barasat

Diab-Eat-Ease, Barasat

700

Common Blood Markers for Breast Cancer

Some key biomarkers tested in blood include:

1. CA 15-3 and CA 27.29 – Proteins that may be elevated in breast cancer patients.

2. CEA (Carcinoembryonic Antigen) – Sometimes used to monitor advanced breast cancer.

3. Circulating Tumor Cells (CTCs) – Cancer cells that break away from a tumor and enter the bloodstream.

4. HER2/neu – A protein that may indicate aggressive breast cancer.

While these tests can be helpful, they are not definitive on their own and are usually combined with imaging tests like mammograms or MRIs.

Who Should Consider a Blood Test for Breast Cancer?

Blood tests may be recommended if:

  • You have a family history of breast cancer.

  • You have unexplained symptoms (e.g., lumps, nipple discharge, or persistent breast pain).

  • You are undergoing treatment and need monitoring.

  • You are at high risk due to genetic factors (e.g., BRCA mutations).

However, blood tests are not yet a primary screening tool for healthy individuals without symptoms.

Symptoms That May Warrant Testing

If you experience any of the following, consult a doctor:

  • A new lump in the breast or armpit

  • Changes in breast size, shape, or texture

  • Nipple discharge (especially bloody)

  • Persistent breast pain

  • Skin changes (dimpling, redness, or scaling)

Early detection saves lives, so never ignore unusual changes in your body.

How Are Blood Tests Done?

The process is simple:

1. A small blood sample is taken from your arm.

2. The sample is sent to a lab for analysis.

3. Results are reviewed by your doctor, who will discuss next steps.

No special preparation is needed, but follow your doctor’s instructions if fasting is required.

Limitations of Blood Tests

While helpful, blood tests have some limitations:

  • Not 100% accurate – False positives or negatives can occur.

  • Not a standalone test – Used alongside imaging and biopsies.

  • Not for everyone – Mostly used for monitoring rather than initial screening.

  • Your doctor will guide you on whether a blood test is right for your situation.

How to Reduce Your Risk of Breast Cancer

While some risk factors (like genetics) can’t be changed, you can lower your risk with healthy habits:

  1. Maintain a healthy weight – Obesity increases breast cancer risk.

  2. Exercise regularly – Aim for 30 minutes most days.

  3. Limit alcohol – Even moderate drinking raises risk.

  4. Eat a balanced diet – Focus on fruits, vegetables, and whole grains.

  5. Avoid smoking – Smoking is linked to many cancers.

  6. Breastfeed if possible – Reduces risk for some women.

  7. Get regular screenings – Follow your doctor’s advice on mammograms.

When to See a Doctor

If you notice any unusual breast changes or have a high risk of breast cancer, don’t wait. Early detection improves treatment success.

  1. Book a consultation with a specialist if you have concerns.

  2. Schedule a mammogram if you’re due for screening.

  3. Discuss genetic testing if you have a strong family history.

Final Thoughts

Blood tests for breast cancer are a promising tool, especially for monitoring and early detection in high-risk individuals. However, they work best alongside other tests like mammograms. Consult your doctor in case you have questions and for further advice. 

Consult a Top oncologist for advice

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Devashish Tripathi, Radiation Specialist Oncologist

Dr Devashish Tripathi

Radiation Specialist Oncologist

20 Years • MBBS, PLAB, MRCP (UK)- General Medicine, FRCR (Oncology), Certificate of Completion of Training (CCT)- Clinical Oncology

Delhi

Apollo Hospitals Indraprastha, Delhi

1500

150 Cashback

1500

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

89%

(25+ Patients)

1000

100 Cashback

2000

No Booking Fees

Dr. Sandeep Muzumder, Radiation Specialist Oncologist

Dr. Sandeep Muzumder

Radiation Specialist Oncologist

21 Years • MBBS (JIPMER, Pondicherry), MD (AIIMS, New Delhi)

Bhubaneswar

Apollo Hospitals Old Sainik School Road, Bhubaneswar

800

1000

No Booking Fees

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

4 Years • MBBS MD(RADIO THERAPY)

Barasat

Diab-Eat-Ease, Barasat

700

Consult a Top oncologist for advice

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Devashish Tripathi, Radiation Specialist Oncologist

Dr Devashish Tripathi

Radiation Specialist Oncologist

20 Years • MBBS, PLAB, MRCP (UK)- General Medicine, FRCR (Oncology), Certificate of Completion of Training (CCT)- Clinical Oncology

Delhi

Apollo Hospitals Indraprastha, Delhi

1500

150 Cashback

1500

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

89%

(25+ Patients)

1000

100 Cashback

2000

No Booking Fees

Dr. Sandeep Muzumder, Radiation Specialist Oncologist

Dr. Sandeep Muzumder

Radiation Specialist Oncologist

21 Years • MBBS (JIPMER, Pondicherry), MD (AIIMS, New Delhi)

Bhubaneswar

Apollo Hospitals Old Sainik School Road, Bhubaneswar

800

1000

No Booking Fees

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

4 Years • MBBS MD(RADIO THERAPY)

Barasat

Diab-Eat-Ease, Barasat

700

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