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Vulvar Cancer Overview and Risk Factors

Learn about vulvar cancer, including its types, symptoms and risk factors. Understand how early detection and awareness can aid in timely diagnosis and improve treatment outcomes.

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Written by Dr. M L Ezhilarasan

Reviewed by Dr. Rohinipriyanka Pondugula MBBS

Last updated on 13th Jan, 2026

Vulvar Cancer

Introduction

Facing a cancer diagnosis can be overwhelming, but understanding the condition is the first step toward managing it effectively. Vulvar cancer, though rare, is a serious health concern that affects women. This article will guide you through the basics of vulvar cancer, its risk factors, and ways to stay informed and proactive about your health.

What Is Vulvar Cancer?

Vulvar cancer occurs when abnormal cells grow uncontrollably in the vulva, the external part of a woman’s genitalia, including the labia, clitoris, vaginal opening, and surrounding skin. While it is not as common as other gynaecological cancers (like cervical or ovarian cancer), early detection and treatment can significantly improve outcomes.

Consult a Gynaecological Oncologist for the best advice

Dr Bhawna Garg, Gynaecological Oncologist

Dr Bhawna Garg

Gynaecological Oncologist

26 Years • MBBS, MS, (PGI MS ROHTAK) FELLOWSHIP GYNECOLOGY ONCOLOGY, (CANCER INSTITUTE CHENNAI)

Delhi

Apollo Hospitals Indraprastha, Delhi

1000

1500

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

95%

(75+ Patients)

1000

1000

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

7 Years • MBBS MD(RADIO THERAPY), CCEBDM

Barasat

Diab-Eat-Ease, Barasat

700

Dr. Revathi S Rajan, Obstetrician and Gynaecologist

Dr. Revathi S Rajan

Obstetrician and Gynaecologist

24 Years • MBBS, DGO, DNB.FFMM

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

900

Dr. Renuka Chandran, Obstetrician and Gynaecologist

Dr. Renuka Chandran

Obstetrician and Gynaecologist

30 Years • MBBS, MD, DGO, Masters in Advanced Ultrasound in Obs & Gynea

Bangalore

Apollo Clinic Bellandur, Bangalore

800

800

Types of Vulvar Cancer

The most common type is squamous cell carcinoma, which develops in the thin, flat cells lining the vulva. Other rare types include:

  • Melanoma (affecting pigment-producing cells)
  • Adenocarcinoma (originating in glandular tissues)
  • Sarcoma (developing in connective tissues)

Symptoms of Vulvar Cancer

Early-stage vulvar cancer may not always cause noticeable symptoms, but as it progresses, you might experience:

  • Itching, burning, or pain in the vulvar area
  • A lump, sore, or wart-like growth that doesn’t heal
  • Skin changes, such as thickening, discoloration, or ulcers
  • Bleeding or discharge not related to menstruation
  • Pain during urination or intercourse

If you notice any of these symptoms, consult a doctor. While these signs don’t always mean cancer, getting them checked early can help rule out serious conditions.

What Causes Vulvar Cancer?

The exact cause is unknown, but certain risk factors increase the likelihood of developing it:

1. Age

Most cases occur in women over 50, particularly after menopause. However, younger women can also be affected.

2. Human Papillomavirus (HPV) Infection

HPV is a sexually transmitted virus linked to several cancers, including vulvar cancer. Some high-risk HPV strains can cause cellular changes leading to cancer over time.

3. Chronic Vulvar Skin Conditions

Conditions like lichen sclerosus (which causes thin, itchy skin) or vulvar intraepithelial neoplasia (VIN) (a precancerous condition) increase risk.

4. Smoking

Tobacco use weakens the immune system and increases vulnerability to HPV-related cancers.

5. Weakened Immune System

Women with HIV/AIDS or those taking immunosuppressive medications have a higher risk.

6. History of Other Cancers

A personal history of cervical or vaginal cancer may increase susceptibility.

How Can You Lower Your Risk?

While some risk factors (like age or genetics) can’t be changed, you can take steps to reduce your risk:

1. Get Vaccinated Against HPV

The HPV vaccine (like Gardasil) protects against high-risk strains. It’s recommended for girls and boys aged 9–26, but some adults up to 45 may also benefit.

2. Practice Safe Sex

Using condoms and limiting sexual partners reduces HPV exposure.

3. Quit Smoking

If you smoke, seek help to quit; this lowers cancer risks significantly.

4. Regular Gynaecological Check-ups

Routine pelvic exams help detect early changes in the vulva. If you have lichen sclerosus or VIN, follow your doctor’s monitoring plan.

5. Be Aware of Changes

Perform regular self-exams and report any unusual symptoms (sores, lumps, persistent itching) to your doctor promptly.

When to See a Doctor?

If you experience persistent vulvar discomfort, unusual growths, or unexplained bleeding, don’t ignore it. Early diagnosis improves treatment success.

Diagnosis May Include:

Diagnosis is done by:

  • Physical examination
  • Biopsy (removing a small tissue sample for testing)
  • Imaging tests (like MRI or CT scans) if cancer is suspected

Treatment Options

Treatment depends on the cancer stage and may include:

  • Surgery (removing the tumor or affected tissue)
  • Radiation therapy (targeting cancer cells with high-energy rays)
  • Chemotherapy (drugs to kill cancer cells)

Your doctor will tailor a plan based on your condition.

Final Thoughts

Vulvar cancer is rare but manageable with early detection. Knowing the symptoms, risk factors, and preventive measures empowers you to take charge of your health. If you have concerns, don’t hesitate to consult a specialist.

Consult a Gynaecological Oncologist for the best advice

Dr Bhawna Garg, Gynaecological Oncologist

Dr Bhawna Garg

Gynaecological Oncologist

26 Years • MBBS, MS, (PGI MS ROHTAK) FELLOWSHIP GYNECOLOGY ONCOLOGY, (CANCER INSTITUTE CHENNAI)

Delhi

Apollo Hospitals Indraprastha, Delhi

1000

1500

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

95%

(75+ Patients)

1000

1000

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

7 Years • MBBS MD(RADIO THERAPY), CCEBDM

Barasat

Diab-Eat-Ease, Barasat

700

Dr. Revathi S Rajan, Obstetrician and Gynaecologist

Dr. Revathi S Rajan

Obstetrician and Gynaecologist

24 Years • MBBS, DGO, DNB.FFMM

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

900

Dr. Renuka Chandran, Obstetrician and Gynaecologist

Dr. Renuka Chandran

Obstetrician and Gynaecologist

30 Years • MBBS, MD, DGO, Masters in Advanced Ultrasound in Obs & Gynea

Bangalore

Apollo Clinic Bellandur, Bangalore

800

800

Consult a Gynaecological Oncologist for the best advice

Dr Bhawna Garg, Gynaecological Oncologist

Dr Bhawna Garg

Gynaecological Oncologist

26 Years • MBBS, MS, (PGI MS ROHTAK) FELLOWSHIP GYNECOLOGY ONCOLOGY, (CANCER INSTITUTE CHENNAI)

Delhi

Apollo Hospitals Indraprastha, Delhi

1000

1500

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

95%

(75+ Patients)

1000

1000

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

7 Years • MBBS MD(RADIO THERAPY), CCEBDM

Barasat

Diab-Eat-Ease, Barasat

700

Dr. Revathi S Rajan, Obstetrician and Gynaecologist

Dr. Revathi S Rajan

Obstetrician and Gynaecologist

24 Years • MBBS, DGO, DNB.FFMM

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

900

Dr. Renuka Chandran, Obstetrician and Gynaecologist

Dr. Renuka Chandran

Obstetrician and Gynaecologist

30 Years • MBBS, MD, DGO, Masters in Advanced Ultrasound in Obs & Gynea

Bangalore

Apollo Clinic Bellandur, Bangalore

800

800

Consult a Gynaecological Oncologist for the best advice

Dr Bhawna Garg, Gynaecological Oncologist

Dr Bhawna Garg

Gynaecological Oncologist

26 Years • MBBS, MS, (PGI MS ROHTAK) FELLOWSHIP GYNECOLOGY ONCOLOGY, (CANCER INSTITUTE CHENNAI)

Delhi

Apollo Hospitals Indraprastha, Delhi

1000

1500

Dr. Amit Choraria, Surgical Oncologist

Dr. Amit Choraria

Surgical Oncologist

18 Years • MBBS, MS (Surgery) Fellow, Surgical Oncology, Tata Medical Center (FSO) Fellow, European Board of Surgery (Surgical Oncology) (FEBS) Fellow, Minimal Access Surgery (FMAS) Fellow, Indian Association of Gastrointestinal Endosurgeons (FIAGES) UICC Fellow, Royal Marsden NHS, London, UK Visiting Scholar, Plastic Reconstructive Surgery, CGMH, Taiwan Fellow, Robotic Surgical Oncology, Vattikuti Foundation, USA

Kolkata

Apollo Multispeciality Hospitals , Kolkata, Kolkata

recommendation

95%

(75+ Patients)

1000

1000

Dr. Rupam Manna, Radiation Specialist Oncologist

Dr. Rupam Manna

Radiation Specialist Oncologist

7 Years • MBBS MD(RADIO THERAPY), CCEBDM

Barasat

Diab-Eat-Ease, Barasat

700

Dr. Revathi S Rajan, Obstetrician and Gynaecologist

Dr. Revathi S Rajan

Obstetrician and Gynaecologist

24 Years • MBBS, DGO, DNB.FFMM

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

900

Dr. Renuka Chandran, Obstetrician and Gynaecologist

Dr. Renuka Chandran

Obstetrician and Gynaecologist

30 Years • MBBS, MD, DGO, Masters in Advanced Ultrasound in Obs & Gynea

Bangalore

Apollo Clinic Bellandur, Bangalore

800

800

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