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Gluten Intolerance Symptoms and Testing Information

Know all about gluten intolerance, what it is, common symptoms, causes, diagnosis and treatment options. Learn about the diet and lifestyle tips for gluten intolerance symptoms.

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Written by Dr. Mohammed Kamran

Reviewed by Dr. M L Ezhilarasan MBBS

Last updated on 2nd Sep, 2025

Gluten Intolerance Symptoms and Testing Information

Introduction 

Gluten intolerance, also known as non-celiac gluten sensitivity (NCGS), is a condition where the body reacts negatively to gluten—a protein found in wheat, barley, and rye. Unlike celiac disease (an autoimmune disorder), gluten intolerance does not damage the intestines but can still cause discomfort and health issues.

If you suspect you may have gluten intolerance, recognising the symptoms and getting the right tests can help you manage your condition effectively. Let’s explore the signs, causes, and ways to diagnose gluten intolerance.

Consult a Gastroenterologist for Personalised Advice

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Dr. Vijay Kumar Rai, Gastroenterology/gi Medicine Specialist

Dr. Vijay Kumar Rai

Gastroenterology/gi Medicine Specialist

18 Years • MBBS , MD (General medicine) , DM (Gastroenterology)

Kolkata

LivGastro, Kolkata

1563

1500

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

Dr. Nikhil Patil, Gastroenterology/gi Medicine Specialist

Dr. Nikhil Patil

Gastroenterology/gi Medicine Specialist

10 Years • MBBS

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

700

Common Symptoms of Gluten Intolerance

Gluten intolerance can affect digestion, energy levels, and overall well-being. Some common symptoms include:

Digestive Issues

•    Bloating
•    Gas
•    Diarrhoea or constipation
•    Stomach pain or cramps

Fatigue and Brain Fog

•    Feeling tired after eating gluten-rich foods
•    Difficulty concentrating
•    Memory lapses

Skin Problems

•     Itchy rashes (dermatitis herpetiformis in rare cases)
•     Eczema or acne flare-ups

Joint and Muscle Pain

•     Unexplained aches
•     Inflammation

Mood Changes

•     Irritability
•     Anxiety or depression

These symptoms usually appear within hours or days after consuming gluten and improve when gluten is removed from the diet.

What Causes Gluten Intolerance?

The exact cause of gluten intolerance is still unclear, but possible factors include:
•     Digestive Sensitivity: Some people struggle to break down gluten properly, leading to discomfort.
•     Gut Bacteria Imbalance: An unhealthy gut microbiome may contribute to sensitivity.
•     Immune Response: While not as severe as celiac disease, some immune reactions may occur.

Unlike celiac disease, gluten intolerance does not cause long-term intestinal damage, but it can still significantly impact quality of life.

How Is Gluten Intolerance Diagnosed?

Since gluten intolerance shares symptoms with other conditions (like celiac disease or irritable bowel syndrome), proper testing is essential.

1. Elimination Diet

The most reliable way to identify gluten intolerance is by:
•     Removing gluten from your diet for 4-6 weeks.
•     Monitoring if symptoms improve.
•     Reintroducing gluten to see if symptoms return.

2. Blood Tests (To Rule Out Celiac Disease)

Before assuming gluten intolerance, doctors may recommend:
•    Celiac disease antibody tests (tTG-IgA, EMA-IgA).
•    Genetic testing (HLA-DQ2/DQ8 genes).

Note: These tests require you to be eating gluten for accurate results.

3. Other Tests

•    Stool tests (for gut inflammation).
•    Breath tests (for bacterial overgrowth).

If tests rule out celiac disease and wheat allergy but symptoms persist, gluten intolerance is likely.

Managing Gluten Intolerance: Diet and Lifestyle Tips

If diagnosed with gluten intolerance, the best approach is a gluten-free diet. Here’s how to manage it effectively:

Foods to Avoid

•    Wheat (bread, pasta, cereals)
•    Barley (malt, beer)
•    Rye
•    Processed foods with hidden gluten (sauces, soups, snacks)

Safe Gluten-Free Alternatives

•    Rice, quinoa, buckwheat
•    Corn, potatoes
•    Gluten-free oats
•    Fruits, vegetables, lean meats, fish

Reading Food Labels

•    Look for "gluten-free" certifications.
•    Avoid ingredients like "modified food starch" or "malt flavouring."

Eating Out Safely

•     Inform restaurant staff about your intolerance.
•     Choose naturally gluten-free dishes (grilled meats, salads without croutons).

Supplements and Gut Health

•    Probiotics may help improve digestion.
•    Vitamin B12 and iron supplements (if deficiencies occur).

When to See a Doctor?

If you experience persistent symptoms, consult a healthcare provider to:
•    Rule out celiac disease or wheat allergy.
•    Get personalised dietary advice.
•    Check for nutrient deficiencies.

Final Thoughts

Gluten intolerance can be challenging, but with the right diet and medical guidance, you can manage it effectively. If you suspect gluten is causing your symptoms, try an elimination diet and consult a doctor for proper testing.

Consult a Gastroenterologist for Personalised Advice

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Dr. Vijay Kumar Rai, Gastroenterology/gi Medicine Specialist

Dr. Vijay Kumar Rai

Gastroenterology/gi Medicine Specialist

18 Years • MBBS , MD (General medicine) , DM (Gastroenterology)

Kolkata

LivGastro, Kolkata

1563

1500

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

Dr. Nikhil Patil, Gastroenterology/gi Medicine Specialist

Dr. Nikhil Patil

Gastroenterology/gi Medicine Specialist

10 Years • MBBS

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

700

Consult a Gastroenterologist for Personalised Advice

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Dr. Vijay Kumar Rai, Gastroenterology/gi Medicine Specialist

Dr. Vijay Kumar Rai

Gastroenterology/gi Medicine Specialist

18 Years • MBBS , MD (General medicine) , DM (Gastroenterology)

Kolkata

LivGastro, Kolkata

1563

1500

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

IMAGE
Dr Rohit Sureka, Gastroenterology/gi Medicine Specialist

Dr Rohit Sureka

Gastroenterology/gi Medicine Specialist

15 Years • MBBS, DNB General Medicine, DNB Gastroenterology

Jaipur

Apollo 247 virtual - Rajasthan, Jaipur

909

Dr. Nikhil Patil, Gastroenterology/gi Medicine Specialist

Dr. Nikhil Patil

Gastroenterology/gi Medicine Specialist

10 Years • MBBS

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

700

Consult a Gastroenterologist for Personalised Advice

Dr. Shivaraj Afzalpurkar, Gastroenterology/gi Medicine Specialist

Dr. Shivaraj Afzalpurkar

Gastroenterology/gi Medicine Specialist

13 Years • MBBS, MD General medicine (Gold medalist), DrNB (Gastroenterology), MNAMS

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

1000

Dr. Vijay Kumar Rai, Gastroenterology/gi Medicine Specialist

Dr. Vijay Kumar Rai

Gastroenterology/gi Medicine Specialist

18 Years • MBBS , MD (General medicine) , DM (Gastroenterology)

Kolkata

LivGastro, Kolkata

1563

1500

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

IMAGE
Dr Rohit Sureka, Gastroenterology/gi Medicine Specialist

Dr Rohit Sureka

Gastroenterology/gi Medicine Specialist

15 Years • MBBS, DNB General Medicine, DNB Gastroenterology

Jaipur

Apollo 247 virtual - Rajasthan, Jaipur

909

Dr. Nikhil Patil, Gastroenterology/gi Medicine Specialist

Dr. Nikhil Patil

Gastroenterology/gi Medicine Specialist

10 Years • MBBS

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

700

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