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Lipaglyn for Fatty Liver: Uses and Effects

Learn about Lipaglyn (Saroglitazar) and its uses for fatty liver conditions like NAFLD and NASH in India. Understand its mechanism, effects on liver fat and inflammation, and other benefits, including for diabetic dyslipidemia.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. J T Hema Pratima MBBS

Last updated on 19th Aug, 2025

Lipaglyn for Fatty Liver: Uses and Effects

Fatty liver disease is a common condition where excess fat builds up in the liver, leading to inflammation and potential liver damage if left untreated. While lifestyle changes like a healthy diet and exercise are the first line of treatment, medications like Lipaglyn can also play a role in managing the condition.

In this article, we’ll discuss what Lipaglyn is, how it helps with fatty liver, its benefits, possible side effects, and other ways to support liver health.

What is Lipaglyn?

Lipaglyn is a brand name for Saroglitazar, a medication primarily used to treat nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes. It belongs to a class of drugs called PPAR (Peroxisome Proliferator-Activated Receptor) agonists, which help regulate fat and sugar metabolism in the body.

How Does Lipaglyn Work?

  • Reduces Liver Fat: Lipaglyn helps lower fat accumulation in the liver by improving how the body processes fats and sugars.
  • Controls Blood Sugar: It enhances insulin sensitivity, helping manage diabetes, which is often linked to fatty liver.
  • Lowers Triglycerides: It reduces harmful fats (triglycerides) in the blood, which contribute to liver damage.

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Who Can Take Lipaglyn?

Lipaglyn is prescribed for:

  • Patients with nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH) – a more severe form of fatty liver with inflammation.
  • People with type 2 diabetes who also have high triglyceride levels.

However, it is not recommended for:

  • Pregnant or breastfeeding women.
  • People with severe liver or kidney disease (unless advised by a doctor).
  • Those allergic to Saroglitazar.
  • Always consult your doctor before starting Lipaglyn to ensure it’s safe for you.

Benefits of Lipaglyn for Fatty Liver

Benefits of lipaglyn for fatty liver are:

1. Reduces Liver Fat: Studies show Lipaglyn can significantly decrease liver fat content, improving liver function.
2. Improves Liver Enzymes: Elevated liver enzymes (like ALT and AST) indicate liver damage. Lipaglyn helps bring them down.
3. Helps with Diabetes & Cholesterol: Since fatty liver is often linked to diabetes and high cholesterol, Lipaglyn helps manage these conditions too.
4. Slows Liver Damage: By reducing inflammation, it may prevent fatty liver from progressing to cirrhosis (severe scarring).

Possible Side Effects of Lipaglyn

Like all medicines, Lipaglyn may cause some side effects, though not everyone experiences them. Common ones include:

  • Mild stomach discomfort (nausea, bloating).
  • Weight gain (due to improved sugar metabolism).
  • Muscle pain or weakness (rare).

Serious side effects (rare but possible):

  • Severe allergic reactions (rash, swelling, difficulty breathing).
  • Liver problems (jaundice, dark urine, severe fatigue).

If you experience any unusual symptoms, stop the medicine and consult your doctor immediately.

Lifestyle Tips to Support Liver Health Alongside Lipaglyn

While Lipaglyn can help, lifestyle changes are crucial for longterm liver health:

1. Eat a Liver-Friendly Diet

  • Reduce sugar & refined carbs (white bread, sweets, sodas).
  • Increase fiber (whole grains, vegetables, fruits).
  • Choose healthy fats (olive oil, nuts, fish).
  • Limit alcohol (as it worsens liver damage).

2. Exercise Regularly

  • 30-45 minutes of walking, cycling, or yoga daily helps burn excess fat.

3. Maintain a Healthy Weight

  • Losing 5-10% of body weight can significantly reduce liver fat.

4. Stay Hydrated

  • Drinking enough water helps flush out toxins.

5. Avoid Unnecessary Medications

  • Some painkillers (like paracetamol in excess) can harm the liver.

When to See a Doctor?

If you have fatty liver and experience:

  • Persistent fatigue
  • Abdominal pain
  • Yellowing of skin/eyes (jaundice)
  • Swelling in legs or abdomen

It’s important to get medical advice. Your doctor may recommend liver function tests, ultrasounds, or FibroScan to assess liver health.

Consult a Top Physician

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

60 Cashback

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

88%

(25+ Patients)

600

500

Dr. M L Ezhilarasan, General Practitioner

Dr. M L Ezhilarasan

General Practitioner

6 Years • MBBS

Visakhapatnam

Apollo 24|7 Clinic - Andhra Pradesh, Visakhapatnam

550

Can I Get Lipaglyn Without a Prescription?

No. Lipaglyn is a prescription-only medication. A doctor will evaluate your condition, liver tests, and overall health before prescribing it.

If you suspect fatty liver or need guidance, you can consult a specialist on Apollo 24|7 for personalized advice.

Final Thoughts

Lipaglyn (Saroglitazar) is a promising medication for fatty liver, especially in people with diabetes or high triglycerides. While it helps reduce liver fat and inflammation, combining it with a healthy diet, exercise, and weight management gives the best results.

If you’re concerned about fatty liver, speak to a doctor for proper diagnosis and treatment options. Early intervention can prevent serious liver damage and improve overall health.

Consult a Top Physician

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

60 Cashback

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

88%

(25+ Patients)

600

500

Dr. M L Ezhilarasan, General Practitioner

Dr. M L Ezhilarasan

General Practitioner

6 Years • MBBS

Visakhapatnam

Apollo 24|7 Clinic - Andhra Pradesh, Visakhapatnam

550

Consult a Top Physician

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

60 Cashback

Dr Aakash Andgi, General Physician/ Internal Medicine Specialist

Dr Aakash Andgi

General Physician/ Internal Medicine Specialist

9 Years • MBBS MD

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

600

60 Cashback

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

88%

(25+ Patients)

600

500

Dr. Thandra Ramoji Babu, General Physician/ Internal Medicine Specialist

Dr. Thandra Ramoji Babu

General Physician/ Internal Medicine Specialist

5 Years • MBBS, DNB(General Medicine)

Warangal

Sai Ram multi-specialty hospital, Warangal

375

400

Dr. M L Ezhilarasan, General Practitioner

Dr. M L Ezhilarasan

General Practitioner

6 Years • MBBS

Visakhapatnam

Apollo 24|7 Clinic - Andhra Pradesh, Visakhapatnam

550

Consult a Top Physician

Dr Syed Mateen Pasha, General Physician

Dr Syed Mateen Pasha

General Physician

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

60 Cashback

Dr Aakash Andgi, General Physician/ Internal Medicine Specialist

Dr Aakash Andgi

General Physician/ Internal Medicine Specialist

9 Years • MBBS MD

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

600

60 Cashback

Dr. Harshendra Jaiswal, General Physician/ Internal Medicine Specialist

Dr. Harshendra Jaiswal

General Physician/ Internal Medicine Specialist

12 Years • MBBS , MD (General medicine)

Kolkata

108 DHANA DHANVANTARI Clinic, Kolkata

recommendation

88%

(25+ Patients)

600

500

Dr. Thandra Ramoji Babu, General Physician/ Internal Medicine Specialist

Dr. Thandra Ramoji Babu

General Physician/ Internal Medicine Specialist

5 Years • MBBS, DNB(General Medicine)

Warangal

Sai Ram multi-specialty hospital, Warangal

375

400

Dr. M L Ezhilarasan, General Practitioner

Dr. M L Ezhilarasan

General Practitioner

6 Years • MBBS

Visakhapatnam

Apollo 24|7 Clinic - Andhra Pradesh, Visakhapatnam

550

Get Your Symptoms Assessed

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