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Causes, Symptoms, and Treatment of Acid Peptic Disease

Learn about the causes, symptoms, and effective treatments for Acid Peptic Disease (APD), a common condition affecting the digestive system. Get insights on managing heartburn, indigestion, and stomach pain to improve your digestive health.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. J T Hema Pratima MBBS

Last updated on 2nd Sep, 2025

Introduction

Acid Peptic Disease (APD) is a common condition that affects the digestive system, particularly the stomach and the first part of the small intestine (duodenum). It includes conditions like gastritis, peptic ulcers, and gastroesophageal reflux disease (GERD). If you frequently experience stomach pain, heartburn, or indigestion, you might be dealing with APD.

The good news is that with the right knowledge and care, APD can be managed effectively. Let’s break down the causes, symptoms, and treatment options in simple terms

What Causes Acid Peptic Disease?

APD occurs when there’s an imbalance between stomach acid and the protective lining of the stomach and intestines. Here are the main causes:

1. Helicobacter pylori (H. pylori) Infection – A common bacterial infection that damages the stomach lining.

2. Excess Stomach Acid Production – Certain foods, stress, or medications can increase acid levels.

3. Long-term Use of NSAIDs – Painkillers like ibuprofen or aspirin can irritate the stomach lining.

4. Smoking and Alcohol – Both weaken the stomach’s protective mucus layer.

5. Spicy or Fatty Foods – Can trigger acid production and worsen symptoms.

6. Stress and Anxiety – While not a direct cause, stress can aggravate symptoms.

Understanding these triggers can help in managing and preventing flare-ups.

Common Symptoms of Acid Peptic Disease

APD can cause various symptoms, depending on its severity. Some common signs include:

  1. Burning stomach pain (especially when the stomach is empty)

  2. Heartburn or acid reflux (a burning sensation in the chest)

  3. Bloating and nausea

  4. Frequent burping or hiccups

  5. Loss of appetite or unexplained weight loss

  6. Black or bloody stools (a sign of bleeding ulcers—seek immediate medical help)

If you experience these symptoms frequently, it’s best to consult a doctor for proper diagnosis and treatment.

Consult an Gastroenterologist for personalized consultation

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

128 Cashback

Dr. Jatin Yegurla, Gastroenterology/gi Medicine Specialist

Dr. Jatin Yegurla

Gastroenterology/gi Medicine Specialist

11 Years • MD (PGI), DM (AIIMS Delhi), FAGIE (AIIMS Delhi), ESEGH (UK), Gold Medalist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

recommendation

92%

(625+ Patients)

1200

150 Cashback

1200

No Booking Fees

Dr. Ankit Vijay Agarwal, Gastroenterology/gi Medicine Specialist

Dr. Ankit Vijay Agarwal

Gastroenterology/gi Medicine Specialist

14 Years • MBBS(Osmania), DNB(Internal Medicine ), DM ( Osmania) Consultant Gastroenterologist, Hepatologist and Advanced Therapeutic Endoscopist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

1200

150 Cashback

1200

No Booking Fees

How Is Acid Peptic Disease Diagnosed?

Doctors use different tests to confirm APD:

1. Endoscopy – A thin tube with a camera is inserted to examine the stomach lining.

2. H. pylori Test – Done through breath, blood, or stool tests.

3. Stool Test – Checks for blood or infection.

4. X-ray with Barium Swallow – Helps detect ulcers or inflammation.

If you suspect APD, booking a consultation with a gastroenterologist can help get the right diagnosis.

Effective Treatment Options for APD

Treatment depends on the cause and severity but usually includes:

1. Medications

  • Antacids – Provide quick relief by neutralizing stomach acid.

  • H2 Blockers (e.g., Ranitidine, Famotidine) – Reduce acid production.

  • Proton Pump Inhibitors (PPIs like Omeprazole, Pantoprazole) – Stronger acid reducers for healing ulcers.

  • Antibiotics – If H. pylori infection is present.

2. Lifestyle Changes

  • Eat smaller, frequent meals instead of large heavy ones.

  • Avoid spicy, fried, and acidic foods (citrus, tomatoes, coffee).

  • Quit smoking and limit alcohol.

  • Manage stress with yoga, meditation, or light exercise.

  • Avoid lying down immediately after meals to prevent reflux.

3. Home Remedies (Supportive Care)

  • Drink coconut water or aloe vera juice to soothe irritation.

  • Chew fennel seeds or ginger to ease digestion.

  • Have a teaspoon of honey (helps reduce inflammation).

If symptoms persist despite these measures, consult a doctor for further evaluation.

When to See a Doctor?

Seek immediate medical attention if you experience:

  1. Severe, persistent stomach pain

  2. Vomiting blood or black, tarry stools

  3. Difficulty swallowing

  4. Sudden weight loss

These could indicate complications like bleeding ulcers or strictures that need urgent care.

Final Thoughts

Acid Peptic Disease is manageable with the right approach—medications, dietary adjustments, and lifestyle changes can make a big difference. If you suspect APD, don’t ignore the symptoms. Early diagnosis and treatment can prevent complications.

Need Help?

If you’re experiencing persistent digestive issues, consider booking a consultation with a gastroenterologist or scheduling a diagnostic test through Apollo 24|7. Early intervention leads to better health! Stay informed, take care of your gut, and live comfortably!

Consult an Gastroenterologist

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

128 Cashback

Dr. Jatin Yegurla, Gastroenterology/gi Medicine Specialist

Dr. Jatin Yegurla

Gastroenterology/gi Medicine Specialist

11 Years • MD (PGI), DM (AIIMS Delhi), FAGIE (AIIMS Delhi), ESEGH (UK), Gold Medalist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

recommendation

92%

(625+ Patients)

1200

150 Cashback

1200

No Booking Fees

Dr. Ankit Vijay Agarwal, Gastroenterology/gi Medicine Specialist

Dr. Ankit Vijay Agarwal

Gastroenterology/gi Medicine Specialist

14 Years • MBBS(Osmania), DNB(Internal Medicine ), DM ( Osmania) Consultant Gastroenterologist, Hepatologist and Advanced Therapeutic Endoscopist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

1200

150 Cashback

1200

No Booking Fees

Consult an Gastroenterologist for personalized consultation

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

128 Cashback

Dr. Jatin Yegurla, Gastroenterology/gi Medicine Specialist

Dr. Jatin Yegurla

Gastroenterology/gi Medicine Specialist

11 Years • MD (PGI), DM (AIIMS Delhi), FAGIE (AIIMS Delhi), ESEGH (UK), Gold Medalist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

recommendation

92%

(625+ Patients)

1200

150 Cashback

1200

No Booking Fees

Dr Piyush Vishwakarma, Gastroenterology/gi Medicine Specialist

Dr Piyush Vishwakarma

Gastroenterology/gi Medicine Specialist

11 Years • MBBS, MD, DrNB,

Delhi

Apollo Hospitals Indraprastha, Delhi

1000

150 Cashback

Dr. Ankit Vijay Agarwal, Gastroenterology/gi Medicine Specialist

Dr. Ankit Vijay Agarwal

Gastroenterology/gi Medicine Specialist

14 Years • MBBS(Osmania), DNB(Internal Medicine ), DM ( Osmania) Consultant Gastroenterologist, Hepatologist and Advanced Therapeutic Endoscopist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

1200

150 Cashback

1200

No Booking Fees

Consult an Gastroenterologist

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr Harish K C, Gastroenterology/gi Medicine Specialist

Dr Harish K C

Gastroenterology/gi Medicine Specialist

15 Years • MBBS MD DM MRCP(UK) (SCE-Gastroenterology and Hepatology)

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

850

128 Cashback

Dr. Jatin Yegurla, Gastroenterology/gi Medicine Specialist

Dr. Jatin Yegurla

Gastroenterology/gi Medicine Specialist

11 Years • MD (PGI), DM (AIIMS Delhi), FAGIE (AIIMS Delhi), ESEGH (UK), Gold Medalist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

recommendation

92%

(625+ Patients)

1200

150 Cashback

1200

No Booking Fees

Dr Piyush Vishwakarma, Gastroenterology/gi Medicine Specialist

Dr Piyush Vishwakarma

Gastroenterology/gi Medicine Specialist

11 Years • MBBS, MD, DrNB,

Delhi

Apollo Hospitals Indraprastha, Delhi

1000

150 Cashback

Dr. Ankit Vijay Agarwal, Gastroenterology/gi Medicine Specialist

Dr. Ankit Vijay Agarwal

Gastroenterology/gi Medicine Specialist

14 Years • MBBS(Osmania), DNB(Internal Medicine ), DM ( Osmania) Consultant Gastroenterologist, Hepatologist and Advanced Therapeutic Endoscopist

Hyderabad

Apollo Hospitals Jubilee Hills, Hyderabad

1200

150 Cashback

1200

No Booking Fees

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