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Signs of Vitamin B12 Deficiency

Know about the cardinal signs of vitamin B12 deficiency, what to do to prevent the deficiency and when to see a specialist

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Written by Dr. J T Hema Pratima

Reviewed by Dr. Vasanthasree Nair MBBS

Last updated on 31st Jul, 2025

Introduction

Vitamin B12 is an essential nutrient that plays a crucial role in keeping your body healthy. It helps in making red blood cells, maintaining nerve function, and supporting brain health. However, many people don’t get enough of this vital vitamin, leading to a deficiency that can cause serious health problems if left untreated.

In this article, we’ll discuss the common signs of Vitamin B12 deficiency, its causes, and how you can manage or prevent it.

What Are the Signs of Vitamin B12 Deficiency?

Vitamin B12 deficiency can develop slowly, and symptoms may appear gradually. Some common signs include:

1. Fatigue and Weakness

One of the earliest signs is feeling unusually tired or weak, even after a good night’s sleep. This happens because your body doesn’t have enough red blood cells to carry oxygen efficiently.

2. Pale or Yellowish Skin

A lack of B12 can lead to a condition called megaloblastic anaemia, where red blood cells are abnormally large and fragile. This can make your skin look pale or slightly yellow (jaundice).

3. Numbness or Tingling in Hands and Feet

Vitamin B12 is essential for nerve health. A deficiency can cause nerve damage, leading to tingling, numbness, or a "pins and needles" sensation in your hands and feet.

4. Difficulty Walking and Balance Problems

If the deficiency affects your nerves severely, you may experience difficulty walking, poor balance, or even muscle weakness.

5. Memory Problems and Confusion

Low B12 levels can impact brain function, leading to memory loss, difficulty concentrating, or even mood changes like depression and irritability.

6. Mouth Ulcers and Glossitis (Swollen Tongue)

Some people develop painful mouth ulcers or a swollen, red tongue (glossitis), making eating uncomfortable.

7. Vision Problems

In rare cases, untreated B12 deficiency can damage the optic nerve, leading to blurred or disturbed vision.

Consult Top Specialists for Personalised Tips

Dr. Bhukya Pavan Kalyan, General Physician

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General Physician

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Bengaluru

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Who Is at Risk of Vitamin B12 Deficiency

Certain groups of people are more likely to develop a B12 deficiency:

  • Vegetarians and Vegans: Since B12 is mainly found in animal products, those who don’t consume meat, eggs, or dairy are at higher risk.

  • Older Adults: As we age, our stomach produces less acid, which is needed to absorb B12 from food.

  • People with Digestive Disorders: Conditions like Crohn’s disease, celiac disease, or gastric bypass surgery can interfere with B12 absorption.

  • Long-Term Users of Certain Medications: Some acid-reducing drugs (like PPIs) and diabetes medications (like metformin) can lower B12 levels.

How Can You Manage or Prevent Vitamin B12 Deficiency?

 1. Eat B12-Rich Foods

Include these in your diet:

  • Meat (beef, chicken, liver)

  • Fish (salmon, tuna)

  • Eggs and dairy products (milk, cheese, yoghurt)

  • Fortified cereals and plant-based milk (for vegetarians/vegans)

2. Consider Supplements

If you’re at risk, your doctor may recommend B12 supplements in the form of tablets, injections, or nasal sprays.

3. Get Regular Check-ups

If you experience symptoms, consult a doctor. A simple blood test can confirm B12 deficiency.

4. Avoid Excessive Alcohol

Heavy drinking can interfere with nutrient absorption, including B12.

When Should You See a Doctor?

If you notice persistent symptoms like extreme fatigue, numbness, or memory issues, it’s important to get tested. Early detection and treatment can prevent long-term complications like nerve damage or anaemia.

Final Thoughts

Vitamin B12 deficiency is common but often overlooked. Recognising the signs early and making simple dietary or lifestyle changes can make a big difference in your health. If you’re experiencing any symptoms, don’t ignore them. Then do not talk to a healthcare provider and take the necessary steps to stay healthy!

Consult Top Nutritionists

Dr. Bhukya Pavan Kalyan, General Physician

Dr. Bhukya Pavan Kalyan

General Physician

5 Years • MBBS DNB Paediatrics

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

650

98 Cashback

Mrs Sneha P V, Nutritionist

Mrs Sneha P V

Nutritionist

10 Years • Master of science in Food and Nutrition

Bengaluru

Apollo Clinic, Sarjapur Road, Bengaluru

400

60 Cashback

600

No Booking Fees

Consult Top Specialists for Personalised Tips

Ms. Lakshmi Tejasvi, Clinical Nutritionist

Ms. Lakshmi Tejasvi

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Vibgyor Nutri, Hyderabad

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Dr. Bhukya Pavan Kalyan, General Physician

Dr. Bhukya Pavan Kalyan

General Physician

5 Years • MBBS DNB Paediatrics

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

650

98 Cashback

Mrs Sneha P V, Nutritionist

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Nutritionist

10 Years • Master of science in Food and Nutrition

Bengaluru

Apollo Clinic, Sarjapur Road, Bengaluru

400

60 Cashback

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No Booking Fees

Dr. Ramalinga Reddy, General Physician

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Consult Top Nutritionists

Ms. Lakshmi Tejasvi, Clinical Nutritionist

Ms. Lakshmi Tejasvi

Clinical Nutritionist

14 Years • M.Sc - Clinical Nutrition

Hyderabad

Vibgyor Nutri, Hyderabad

750

No Booking Fees

Dr. Bhukya Pavan Kalyan, General Physician

Dr. Bhukya Pavan Kalyan

General Physician

5 Years • MBBS DNB Paediatrics

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

650

98 Cashback

Mrs Sneha P V, Nutritionist

Mrs Sneha P V

Nutritionist

10 Years • Master of science in Food and Nutrition

Bengaluru

Apollo Clinic, Sarjapur Road, Bengaluru

400

60 Cashback

600

No Booking Fees

Dr. Ramalinga Reddy, General Physician

Dr. Ramalinga Reddy

General Physician

5 Years • MBBS MD General medicine

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

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Dt. Ila Sharma, Clinical Nutritionist

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Clinical Nutritionist

18 Years • Master in food & Nutrition

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VIPUL GREENS - SOCIETY CLINIC, Gurugram

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