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Dried Blood Spot Test Overview and Procedure

Learn what a Dried Blood Spot (DBS) test is, how it’s done, its advantages, limitations, and common uses in newborn screening, infectious disease testing, drug monitoring, and more.

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Written by Dr. Siri Nallapu

Reviewed by Dr. Mohammed Kamran MBBS, FIDM

Last updated on 29th Aug, 2025

dried test

When it comes to medical testing, convenience and accuracy are key. The Dried Blood Spot (DBS) Test is a simple yet effective method that allows for easy sample collection and reliable results. If you're unfamiliar with this test or wondering how it works, this guide will walk you through everything you need to know in a simple, friendly manner.

What Is a Dried Blood Spot Test?

A Dried Blood Spot (DBS) Test is a diagnostic method where a few drops of blood are collected on a special filter paper, allowed to dry, and then sent to a lab for analysis. Unlike traditional blood tests that require large samples drawn from a vein, this test only needs a small prick on the fingertip, making it less invasive and more convenient.

This test is commonly used for:

  • Newborn screening (to check for genetic disorders)
  • Infectious disease testing (like HIV, hepatitis, or COVID-19 antibodies)

Metabolic and genetic disorder testing

  • Therapeutic drug monitoring (to measure medication levels in the blood)
  • Nutritional deficiency checks (such as vitamin D or iron levels)

How Is the Dried Blood Spot Test Done?

One of the biggest advantages of this test is its simplicity. Here’s how it works:

Step 1: Preparation

  • No fasting is usually required unless specified by your doctor.
  • The area (usually a fingertip) is cleaned with an alcohol swab.

Step 2: Blood Collection

  • A small lancet (a tiny needle) is used to prick the fingertip.
  • A few drops of blood are collected onto a special absorbent paper (filter paper).

Step 3: Drying & Storage

  • The blood spots are left to dry for a few hours.
  • Once dry, the sample is sealed and sent to a laboratory for testing.

Step 4: Lab Analysis

  • The lab extracts and analyzes the dried blood for specific markers.
  • Results are usually available within a few days to a week, depending on the test.

Why Choose a Dried Blood Spot Test?

1. Less Invasive

  • No need for large needles or vials of blood—just a tiny finger prick!

2. Convenient

  • Can be done at home with a self-collection kit or at a clinic.
  • Ideal for babies, children, and people who fear needles.

3. Stable & Easy to Transport

  • Dried blood remains stable at room temperature, unlike liquid blood samples that require refrigeration.

4. Cost-Effective

  • Requires less lab processing, making it more affordable than traditional blood tests.

Who Should Consider This Test?

  • Parents – For newborn screening to detect early health issues.
  • People with chronic conditions – To monitor medication levels (e.g., epilepsy or psychiatric drugs).
  • Those in remote areas – Since samples can be mailed to labs easily.
  • Individuals needing frequent testing – Less discomfort compared to regular blood draws.

Consult an Specialist for the best advice

Dr. Rajib Ghose, General Practitioner

Dr. Rajib Ghose

General Practitioner

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

26 Years • MBBS

Kolkata

B Ghose Foundation Doctor's Chamber, Kolkata

recommendation

92%

(25+ Patients)

1063

850

Dr. Abhishek Gowda, General Physician/ Internal Medicine Specialist

Dr. Abhishek Gowda

General Physician/ Internal Medicine Specialist

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Are There Any Limitations?

While the DBS test is highly useful, it may not be suitable for all types of tests. Some limitations include:

  • Small sample size – May not be enough for multiple tests.
  • Not all labs offer DBS testing – Check availability before opting for it.
  • Possible contamination – If not collected properly, results may be affected.

How to Prepare for the Test?

  • Follow any specific instructions from your doctor (e.g., fasting if required).
  • Stay hydrated to make blood collection easier.
  • Avoid excessive hand movement before the test to prevent bruising.

Where Can You Get a Dried Blood Spot Test?

Many hospitals, diagnostic centers, and home-testing services offer DBS testing. If you're looking for a convenient and reliable option, you can book a Dried Blood Spot Test through Apollo 24|7. Their expert team ensures accurate sample collection and quick results.

How to Book?

1. Visit Apollo 24|7’s website or download the app.
2. Search for "Dried Blood Spot Test."
3. Choose between home collection or lab visit.
4. Schedule your test at your preferred time.

Final Thoughts

The Dried Blood Spot Test is a game-changer in medical diagnosis; simple, painless, and efficient. Whether you're a parent, a patient needing regular monitoring, or someone who prefers hassle-free testing, this method offers a great alternative to traditional blood draws.

If you think this test might be right for you, consult your doctor or book a test through Apollo 24|7 for a seamless experience. Stay informed, stay healthy!

Would you like to know more about specific conditions detected by DBS testing?

Consult an Specialist for the best advice

Dr. Rajib Ghose, General Practitioner

Dr. Rajib Ghose

General Practitioner

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

26 Years • MBBS

Kolkata

B Ghose Foundation Doctor's Chamber, Kolkata

recommendation

92%

(25+ Patients)

1063

850

Dr. Abhishek Gowda, General Physician/ Internal Medicine Specialist

Dr. Abhishek Gowda

General Physician/ Internal Medicine Specialist

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Consult an Specialist for the best advice

Dr. Swathi Reddy Perugu, General Physician/ Internal Medicine Specialist

Dr. Swathi Reddy Perugu

General Physician/ Internal Medicine Specialist

7 Years • MBBS, MD (General Medicine)

Hyderabad

Health plus, Hyderabad

625

Dr. Rajib Ghose, General Practitioner

Dr. Rajib Ghose

General Practitioner

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

26 Years • MBBS

Kolkata

B Ghose Foundation Doctor's Chamber, Kolkata

recommendation

92%

(25+ Patients)

1063

850

Dr. Abhishek Gowda, General Physician/ Internal Medicine Specialist

Dr. Abhishek Gowda

General Physician/ Internal Medicine Specialist

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

Consult an Specialist for the best advice

Dr. Swathi Reddy Perugu, General Physician/ Internal Medicine Specialist

Dr. Swathi Reddy Perugu

General Physician/ Internal Medicine Specialist

7 Years • MBBS, MD (General Medicine)

Hyderabad

Health plus, Hyderabad

625

Dr. Rajib Ghose, General Practitioner

Dr. Rajib Ghose

General Practitioner

25 Years • MBBS

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

950

850

Dr. Chethan T L, General Physician/ Internal Medicine Specialist

Dr. Chethan T L

General Physician/ Internal Medicine Specialist

5 Years • MBBS, MD, DNB (General Medicine)

Bengaluru

Apollo Medical Center, Marathahalli, Bengaluru

550

83 Cashback

Dr. Rajib Ghose, General Physician/ Internal Medicine Specialist

Dr. Rajib Ghose

General Physician/ Internal Medicine Specialist

26 Years • MBBS

Kolkata

B Ghose Foundation Doctor's Chamber, Kolkata

recommendation

92%

(25+ Patients)

1063

850

Dr. Abhishek Gowda, General Physician/ Internal Medicine Specialist

Dr. Abhishek Gowda

General Physician/ Internal Medicine Specialist

2 Years • MBBS

Bengaluru

PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

400

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