Hydroxychloroquine and Alcohol: Key Considerations
Wondering if you can drink alcohol while taking hydroxychloroquine? Learn about possible side effects, liver health risks, and safe drinking guidelines for HCQ users.
Written by Dr. Dhankecha Mayank Dineshbhai
Reviewed by Dr. Shaik Abdul Kalam MD (Physician)
Last updated on 20th Aug, 2025
If you're taking hydroxychloroquine (HCQ) for conditions like rheumatoid arthritis, lupus, or malaria, you might wonder whether it's safe to consume alcohol. While moderate drinking may not always cause severe interactions, there are important factors to consider. This article will help you understand how alcohol may affect your treatment and overall health when taking HCQ.
What Is Hydroxychloroquine (HCQ)?
Hydroxychloroquine is a medication primarily used to treat autoimmune diseases such as rheumatoid arthritis and lupus. It helps reduce inflammation, pain, and swelling. It is also prescribed for the prevention and treatment of malaria. HCQ works by suppressing the immune system's overactivity, which is beneficial in autoimmune conditions.
Can You Drink Alcohol While Taking HCQ?
There is no direct, severe interaction between hydroxychloroquine and alcohol, but healthcare professionals generally advise caution. Here’s why:
1. Increased Risk of Side Effects
- Both HCQ and alcohol can cause gastrointestinal issues like nausea, stomach pain, and diarrhoea. Drinking alcohol may worsen these side effects.
- Alcohol can also increase dizziness or drowsiness, which are possible side effects of HCQ.
2. Liver Health Considerations
- HCQ is metabolised (broken down) by the liver. Alcohol is also processed in the liver, and excessive drinking can strain liver function.
- If you have existing liver conditions, combining HCQ and alcohol may further stress your liver.
3. Reduced Medication Effectiveness
- Alcohol can interfere with the immune system and may reduce the effectiveness of HCQ in managing autoimmune diseases.
How Much Alcohol Is Safe?
If your doctor approves occasional alcohol consumption, follow these guidelines:
- Moderation is key: Limit yourself to one standard drink per day for women and up to two for men.
- Avoid binge drinking: Heavy alcohol use can worsen side effects and liver health.
- Monitor your body’s response: If you experience increased dizziness, nausea, or fatigue, avoid alcohol.
Who Should Avoid Alcohol Completely?
Certain individuals should avoid alcohol entirely while on HCQ:
- Those with liver disease or impaired liver function.
- Patients with a history of alcohol dependency.
- People experiencing severe side effects from HCQ.
Tips for Safe Use of HCQ
- Follow Your Doctor’s Advice – Always take HCQ as prescribed and discuss alcohol consumption with your healthcare provider.
- Stay Hydrated – Drinking water helps minimize side effects like nausea.
- Monitor Liver Health – If you drink occasionally, get regular liver function tests.
- Avoid Alcohol on an Empty Stomach – Food can help reduce irritation caused by alcohol and medication.
When to Seek Medical Help
If you experience any of the following after combining HCQ and alcohol, consult your doctor immediately:
- Severe stomach pain or vomiting
- Yellowing of skin or eyes (jaundice)
- Unusual fatigue or weakness
- Vision changes (HCQ can rarely affect the eyes)
Final Thoughts
While an occasional drink may not be harmful for most people taking HCQ, it’s best to consult your doctor before consuming alcohol. Your medical history, liver health, and overall condition play a role in determining whether alcohol is safe for you.
If you have concerns about HCQ and alcohol interactions or need personalized advice, consider booking a consultation with a specialist through Apollo 24|7. Early guidance can help you manage your condition safely and effectively.
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