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Oral Cancer Treatment Options and Approaches

Explore the treatment options for oral cancer—including surgery, radiation, chemotherapy, and more. Learn what to expect during recovery and how to manage side effects for better outcomes.

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Written by Dr. Vasanthasree Nair

Reviewed by Dr. J T Hema Pratima MBBS

Last updated on 20th Aug, 2025

Facing a diagnosis of oral cancer can be overwhelming, but understanding your treatment options can help you make informed decisions. This guide will walk you through the different approaches to treating oral cancer, what to expect, and how to manage your health during and after treatment.

What Is Oral Cancer?

Oral cancer refers to cancers that develop in the mouth, including the lips, tongue, gums, inner cheeks, roof or floor of the mouth, and throat. Early detection is crucial for successful treatment, so knowing the signs and seeking medical advice promptly can make a big difference.

Common Symptoms of Oral Cancer

If you experience any of the following symptoms for more than two weeks, consult a doctor:

  • A sore or ulcer in the mouth that doesn’t heal

  • Red or white patches inside the mouth

  • Persistent pain or discomfort in the mouth

  • Difficulty swallowing or chewing

  • A lump or thickening in the cheek or neck

  • Unexplained weight loss

  • Persistent bad breath

Treatment Options for Oral Cancer

The treatment plan depends on the cancer’s stage, location, and overall health. Here are the most common approaches:

1. Surgery

Surgery is often the first step if the tumour is small and localised. The goal is to remove the cancerous tissue while preserving as much healthy tissue as possible.

  • Excision: The surgeon removes the tumour and a small margin of healthy tissue.

  • Glossectomy: Partial or complete removal of the tongue if cancer affects it.

  • Mandibulectomy: Removal of part or all of the jawbone if cancer has spread.

  • Neck Dissection: Removal of lymph nodes if cancer has spread.

Recovery Tips After Surgery:

  • Follow a soft or liquid diet as advised.

  • Practice good oral hygiene to prevent infections.

  • Attend speech or swallowing therapy if needed.

Consult Top Specialists

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

135 Cashback

900

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

150 Cashback

2000

No Booking Fees

2. Radiation Therapy

Radiation uses high-energy beams to kill cancer cells. It may be used alone for early-stage cancer or combined with surgery or chemotherapy for advanced cases.

  • External Beam Radiation: Targeted radiation from outside the body.

  • Brachytherapy: Radioactive seeds placed near the tumour (less common for oral cancer).

Managing Side Effects:

  • Dry mouth – Stay hydrated and use saliva substitutes.

  • Mouth sores – Rinse with saltwater or prescribed mouthwash.

  • Fatigue – Rest well and eat nutritious meals.

3. Chemotherapy

Chemotherapy uses drugs to kill cancer cells or stop their growth. It’s often combined with radiation (chemoradiation) for better effectiveness.

Common Side Effects & How to Manage Them:

  • Nausea – Take anti-nausea medications as prescribed.

  • Hair loss – Temporary; consider wigs or head coverings.

  • Weak immune system – Avoid infections by practising good hygiene.

4. Targeted Therapy

This treatment targets specific genes or proteins in cancer cells, minimising damage to healthy cells. Drugs like Cetuximab may be used for advanced oral cancer.

5. Immunotherapy

Immunotherapy boosts the body’s immune system to fight cancer. Drugs like Pembrolizumab may be used if other treatments aren’t effective.

Lifestyle Changes to Support Recovery

  • Quit Smoking & Alcohol: Both increase cancer risk and hinder healing.

  • Eat a Balanced Diet: Soft, nutrient-rich foods help recovery.

  • Oral Hygiene: Brush gently and use alcohol-free mouthwash.

  • Regular Follow-ups: Monitor for recurrence or side effects.

When to See a Doctor?

If you notice persistent mouth sores, lumps, or unusual symptoms, don’t delay—early detection saves lives.

Need Expert Advice?

Apollo24|7 offers consultations with top oncologists. You can book an appointment or schedule tests easily from home.

Conclusion 

Oral cancer treatment has come a long way, and many people recover fully with timely care. Stay positive, follow your doctor’s advice, and lean on loved ones for support.

Consult Top Specialists

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

135 Cashback

900

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

150 Cashback

2000

No Booking Fees

Consult Top Specialists

Dr Sunita Samleti, Oncologist

Dr Sunita Samleti

Oncologist

18 Years • M.D. (Pathology)- TN Medical College, Mumbai University, Mumbai, Mar 2005 M.B.B.S. Grant Medical College, Mumbai University, Mumbai, Oct 1999

Chinagadila

Apollo Hospitals Health City Unit, Chinagadila

600

60 Cashback

600

Dr Gowshikk Rajkumar, Oncologist

Dr Gowshikk Rajkumar

Oncologist

10 Years • MBBS, DMRT, DNB in Radiation oncology

Bengaluru

Apollo Clinic, JP nagar, Bengaluru

900

135 Cashback

900

No Booking Fees

Dr. Sanchayan Mandal, Oncologist

Dr. Sanchayan Mandal

Oncologist

17 Years • MBBS, DNB Raditherapy, DrNB Medical Oncology

East Midnapore

VIVEKANANDA SEBA SADAN, East Midnapore

1500

Dr.sanchayan Mandal, Oncologist

Dr.sanchayan Mandal

Oncologist

17 Years • MBBS, DrNB( MEDICAL ONCOLOGY), DNB (RADIOTHERAPY),ECMO. PDCR. ASCO

Kolkata

Dr. Sanchayan Mandal Oncology Clinic, Kolkata

1500

1500

No Booking Fees

Dr. Gopal Kumar, Head, Neck and Thyroid Cancer Surgeon

Dr. Gopal Kumar

Head, Neck and Thyroid Cancer Surgeon

15 Years • MBBS, MS , FARHNS ( Seoul, South Korea ), FGOLF ( MSKCC, New York )

Delhi

Apollo Hospitals Indraprastha, Delhi

recommendation

90%

(25+ Patients)

1500

150 Cashback

2000

No Booking Fees

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