PCOS and Hypothyroidism
Explore the link between PCOS and hypothyroidism, two hormonal disorders that affect women’s reproductive and metabolic health. Learn about causes, symptoms, diagnosis, and treatment options for better management.
Written by Dr Sonia Bhatt
Last updated on 3rd Jul, 2025
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that affects the reproductive health of women. The characteristics of this condition include irregular menstrual cycles, hormonal imbalance, and small cysts in the ovaries. As a result, PCOS is one of the major reasons behind the reproductive issues with women.
On the other hand, hypothyroidism is a condition where the thyroid gland fails to produce enough hormones. As a result, essential bodily functions get hampered. Usually, these hormones are important to regulate metabolism, energy production, heart rate, etc.
Now, the connection between PCOS and hypothyroidism is intricate. Since both conditions involve hormonal dysregulation, they can exacerbate each other. Therefore, understanding both conditions in detail is important for their effective management and improving quality of life.
Causes
Here are the details on the causes of PCOS and hypothyroidism –
Causes of PCOS
While the causes of PCOS remain unclear, some of the contributing factors include –
- Genetics: Individuals with a family history of PCOS remain at risk of developing this condition.
- Lifestyle reasons: Being overweight, indulging in smoking and drinking alcohol, consuming processed food, etc., contribute to the development of this condition.
- Hormonal imbalances: Elevated levels of male hormones like testosterone disrupt regular ovarian functions.
Causes of Hypothyroidism
Some of the leading reasons for hypothyroidism are –
- Autoimmune disorders: Autoimmune disorders like Hashimoto’s thyroiditis are one of the major causes of hypothyroidism.
- Iodine deficiency: Iodine deficiency is one of the leading causes of hypothyroidism.
- Medications: Specific medications, especially related to hyperthyroidism, can lead to this thyroid disorder.
- Exposure to radiation: Prolonged exposure to radiation, especially during childhood, also leads to this condition.
Shared Risk Factors
PCOS and hypothyroidism share multiple risk factors. These are –
- Metabolic changes: Both these conditions alter the metabolic rate in females. Hence, they develop insulin resistance, gain weight, hyperglycaemia, etc.
- Damages endocrine system: Both these conditions damage the human endocrine system, which manages the hormone production for the body.
Symptoms
Some of the highlighting symptoms of these conditions are –
Owing to the overlapping symptoms, it becomes challenging to distinguish between the two conditions without proper medical evaluation.
Diagnosis
Here is all you need to know about the diagnosis criteria of PCOS and hypothyroidism –
Diagnostic criteria of PCOS
- Irregular ovulation or anovulation
- Polycystic ovaries observed on ultrasound
- High levels of testosterone
Diagnostic criteria of hypothyroidism
- High TSH (Thyroid Stimulating Hormone) levels
- Low T4 (thyroxine) levels
Tests used to determine the coexistence
Here are some clinical tests that are used to determine the coexistence of both these conditions –
- Blood tests to determine TSH, T3, T4, and androgen levels
- Pelvic ultrasound to identify ovarian cysts
- Insulin and glucose tolerance tests
- Antibody tests to check autoimmune thyroid disorders
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Impact on fertility
Here are more details on how PCOS and hypothyroidism affect the reproductive health of women –
PCOS and its effect on the reproductive health of women
PCOS significantly affects the reproductive health of women. The irregular ovulation is the major reason behind it, but high androgen levels and insulin resistance further complicate the matter. Additionally, untreated PCOS increases the likelihood of developing endometrial hyperplasia, which can also impact fertility.
Effects of hypothyroidism on the reproductive health of women
Hypothyroidism can also impact the fertility of women through the disruption in ovulation. Besides impairing embryo development in the early stages, this condition also increases the risk of miscarriage during pregnancy.Moreover, hypothyroidism also causes luteal phase defects, reducing the chances of successful implantation.
Managing fertility challenges with both conditions
Here are some guidance on the process of managing fertility challenges with these two conditions –
- Medical intervention: Medical intervention is a way to deal with these two conditions. After the required tests and their results, the doctors will prescribe medicines that will successfully address both conditions.
- Restoring hormone levels: Doctors also use drugs like levothyroxine to restore normal hormone levels that help patients deal with this condition.
- Using assisted reproductive technologies (ART): Doctors also suggest that patients suffering from these conditions opt for ARTs like IVF (in vitro Fertilisation) or IUI (intrauterine insemination) in case they are failing to conceive normally.
- Making lifestyle changes: Doctors also ask patients to make necessary lifestyle changes, including opting for a healthy diet, regular exercise, quitting smoking and drinking, etc., to manage these conditions.
- Regular monitoring: Regular monitoring through clinical tests is also important in managing these two conditions.
Treatment options
The treatment options for both these conditions include –
Treatment strategies for PCOS
- Medications, which will include drugs for insulin resistance and hormone regulation. They can also try medicines to stimulate ovulation.
- Lifestyle changes where patients shift to a healthier diet and exercise regularly.
- Acupuncture also helps manage PCOS.
Treatment strategies for hypothyroidism
Incorporating a healthy diet that has ample iodine, selenium, and other minerals is important to deal with this thyroid condition. Also, doctors prescribe levothyroxine, which restores the hormonal deficiency and manages this condition.
Managing both conditions
Women who are suffering from both PCOS and hypothyroidism can manage these conditions by combining both their treatment plans. However, they must do it under the guidance of a doctor.
Lifestyle and Diet Recommendations
In terms of lifestyle and dietary modifications, here are some changes that patients need to make –
Lifestyle changes for managing PCOS
One of the most important lifestyle changes that women with PCOS need to opt for is regular exercise. In short, they need to adopt an active lifestyle that includes ample physical activities. It improves hormone regulation and insulin sensitivity.
Also, they need to manage their stress better. They can use yoga and meditation to get the best results.
Dietary modifications for hypothyroidism
In terms of dietary recommendations for hypothyroidism, individuals need to include whole-grain foods, limit goitrogens and include essential minerals. Together, they create a balanced diet that helps manage this condition better.
An overall approach to a healthier lifestyle
- Combining strategies for managing PCOS and hypothyroidism include:
- Maintaining a balanced diet to support metabolic health.
- Consistent exercise routines to manage weight and improve hormone levels.
- Regular medical follow-ups to monitor progress.
Long-term health implications
Here are the long-term health implications of PCOS and hypothyroidism –
Long-term effect of PCOS
PCOS, if left untreated, can lead to –
- Type 2 diabetes
- Cardiovascular issues
- Endometrial cancer
Long-term effects of hypothyroidism
Hypothyroidism, if left untreated, can lead to –
- Heart disease
- Depression and memory loss
- Myxedema
The combined impact on overall health
PCOS and hypothyroidism together can amplify metabolic and cardiovascular risks, highlighting the importance of early intervention.
Research and Future Directions
The current research suggests that there is an interplay between PCOS and hypothyroidism. Several studies have proved that women with PCOS have a higher risk of developing hypothyroidism and vice versa.
Now, in terms of future directions, there has been considerable advancement in medicines, and new targeted therapies are being introduced to manage these two conditions.
Conclusion
PCOS and hypothyroidism are two interconnected conditions that pose a significant threat to women’s health, especially their ability to reproduce. However, the symptoms of these two conditions are widely published, making them easy to understand. Hence, early intervention and treatment can easily help individuals to get better.
Having said that, the treatment of these two conditions requires a comprehensive approach. By combining medical treatment, lifestyle modifications, and regular monitoring, one can manage PCOS and hypothyroidism effectively, ensuring better outcomes.
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