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Effects of Low Vitamin B12 Levels

Low vitamin B12 levels can cause fatigue, neurological issues, anemia, and cognitive decline. Early detection and treatment are essential to prevent long-term health complications.

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Written by Dr. Shaik Abdul Kalam

Reviewed by Dr. Siri Nallapu MBBS

Last updated on 20th Aug, 2025

Introduction

Vitamin B12 is an essential nutrient that plays a crucial role in keeping our bodies healthy. It helps in forming red blood cells, maintaining nerve function, and supporting DNA production. However, when your body doesn’t get enough Vitamin B12, it can lead to various health problems.

In this article, we’ll explore the effects of low Vitamin B12 levels, its symptoms, causes, and how you can manage it effectively.

What Happens When Vitamin B12 Levels Are Low?

Vitamin B12 deficiency can affect multiple body functions, leading to both physical and neurological symptoms. Some of the most common effects include:

1. Fatigue and Weakness

Since Vitamin B12 is essential for red blood cell production, low levels can lead to anaemia, where your body doesn’t have enough healthy red blood cells to carry oxygen. This can make you feel extremely tired, weak, and short of breath.

2. Nerve Problems

Vitamin B12 is vital for nerve health. A deficiency can cause:

  • Tingling or numbness in hands and feet (peripheral neuropathy)

  • Balance problems

  • Memory loss or confusion

  • Mood changes (depression or irritability)

3. Digestive Issues

Some people with low B12 levels experience:

  • Loss of appetite

  • Weight loss

  • Constipation or diarrhoea

4. Heart Palpitations

Due to anaemia, your heart may beat faster to compensate for low oxygen levels, leading to irregular heartbeats or palpitations.

5. Pale or Yellowish Skin

A lack of red blood cells can make your skin look pale or slightly yellow (jaundice).

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Who Is at Risk of Vitamin B12 Deficiency?

Certain groups of people are more likely to develop a Vitamin B12 deficiency:

  • Strict vegetarians or vegans: Since B12 is mainly found in animal products, those who don’t consume meat, eggs, or dairy may lack sufficient intake.

  • Older adults: As we age, stomach acid production decreases, making it harder to absorb B12 from food.

  • People with digestive disorders: Conditions like celiac disease, Crohn’s disease, or atrophic gastritis can interfere with B12 absorption.

  • Those who have had weight loss surgery: Some procedures reduce the stomach’s ability to absorb nutrients.

  • Long-term users of certain medications: Acid-reducing drugs (like PPIs) and diabetes medications (metformin) can lower B12 levels.

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How to Improve Vitamin B12 Levels?

If you suspect a deficiency, consult a doctor for a blood test. Depending on the severity, treatment may include:

1. Dietary Changes

Include more B12-rich foods in your diet, such as:

  • Meat (beef, chicken, fish)

  • Eggs and dairy products (milk, cheese, yoghurt)

  • Fortified cereals and plant-based milk (for vegetarians/vegans)

2. Supplements

  • Oral supplements: For mild deficiencies, doctors may recommend B12 tablets.

  • Injections: In severe cases, especially if absorption is an issue, B12 injections may be necessary.

3. Lifestyle Adjustments

  • If you’re vegetarian, consider fortified foods or supplements.

  • Limit alcohol, as excessive drinking can worsen B12 absorption.

  • Manage underlying conditions (like diabetes or digestive disorders) that may contribute to deficiency.

When to See a Doctor?

If you experience persistent symptoms like:

  • Extreme fatigue

  • Numbness in hands/feet

  • Memory problems

  • Unexplained weight loss

It’s important to get tested. Early detection and treatment can prevent long-term complications like nerve damage.

You can book a Vitamin B12 test or consult a doctor through Apollo 24|7 for expert advice and personalised care.

Conclusion

Vitamin B12 deficiency is common but often overlooked. Recognising the symptoms early and taking corrective steps—whether through diet, supplements, or medical treatment—can help restore your energy, improve nerve function, and enhance overall well-being.

If you suspect a deficiency, don’t ignore it. A simple blood test can make a big difference in your health!

Consult Top Nutritionists

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Consult Top Specialists for Personalised Tips

Dr. Bhukya Pavan Kalyan, General Physician

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Dr. Bhukya Pavan Kalyan, General Physician

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PRESTIGE SHANTHINIKETAN - SOCIETY CLINIC, Bengaluru

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Dr. Ramalinga Reddy, General Physician

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Dt. Ila Sharma, Clinical Nutritionist

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Dr Sumanth R, General Physician

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Dr. Sasikamalam, General Practitioner

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