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Why is lower oxygen affinity in hb better at higher altitudes?
At higher altitudes such as on top of a mountain, the air is less dense and this means that the partial pressure of oxygen is lower.
Last updated on 19 May 2023
High hemoglobin level is most often caused by low oxygen levels in the blood (hypoxia), present over a long period of time. Common reasons includes bone marrow disease that causes abnormal increase in red blood cells (polycythemia vera) Congenital heart disease and heavy smoking.
Humans can survive at high altitudes. However, if you go to a high altitude, your body needs to adjust properly by getting used to it slowly or you could get sick.
If you have altitude sickness you should first acclimatise with the enviroment for 24-48 hours before stepping out to do any activity.
Supplemental oxygen is required above 10,000 feet
Humans can certainly experience reverse altitude sickness, known as high-altitude de acclimatisation syndrome (HADAS). When people who live at low altitude have adjusted to a high-altitude, low-oxygen environment, they can get any of a large number of possible symptoms of HADAS when returning to a lower altitude.
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