17-Alpha-Hydroxyprogesterone (17-Ohp)

The 17-Oh Progesterone test is performed to check for congenital adrenal hyperplasia (CAH), caused due to the high levels of the 17-Oh Progesterone hormone. CAH is a glandular disorder that decreases the amount of cortisol produced by the adrenal glands. It may also increase the production of male sex hormones.

The 17-Oh Progesterone hormone is produced by the adrenal glands, that are two small glands located on top of each kidney It is then converted to a hormone called cortisol, along with special enzymes or proteins. Cortisol plays a pivotal role in the body, helping regulate metabolism and the immune system.

Usually, cortisol is released in varying but controlled amounts. But during physical or emotional stress, high levels of this hormone are released.

When there is a cortisol deficiency in the body due to the lack of appropriate enzymes, the build-up of the 17-Oh Progesterone hormone occurs leading to CAH.

The 17-Oh Progesterone test is usually done on newborn babies, but it is recommended for anyone who develops CAH-related symptoms down the line. Some of the symptoms of the abundance of 17-Oh Progesterone hormone in males include:

• Early onset of puberty, usually beginning by the age of 2 or 3
• Well-defined muscles early
• A large penis and small testes
• Infertility

Similarly, the 17-Oh Progesterone test is done for women with:

• Irregular periods
• Deep voice
• Genitalia with both male and female characteristics, but visually more male-like
• Excessive and early hair growth
• Infertility

If you face any of these symptoms, it is advisable to get the test done. The 17-Oh Progesterone test is a simple blood test where the lab professional will draw your blood from a vein or artery in your hand. For infants, the 17-Oh Progesterone test is performed by a simple heel prick.

The subsequent results of the 17-Oh Progesterone test may depend on multiple factors like age, sex, and testing methods. However, the expected results usually lie in the range provided below:

• Newborn babies: 1,000-3,000 nanograms/decilitre (ng/dL)
• Children older than 24 hours: less than 100 ng/dL
• Adults: less than 200 ng/dL

To catch this condition early, it is recommended to get tested as soon as possible. Apollo 24/7 offers a comprehensive 17-Oh Progesterone test for the same.