Ana By Immunoblot

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  • Ana By Immunoblot

    17 tests included



blood sample




Age group

7 years & above

Autoimmune conditions are becoming increasingly common these days, and their diagnosis and treatment can be a complex process. One of the most common laboratory tests conducted for autoimmune conditions is the ANA (Antinuclear Antibody) test. It is a type of blood test that detects the presence of autoantibodies in the body that attack its cells and tissues. The ANA by immunoblot panel helps diagnose autoimmune disorders such as rheumatoid arthritis, lupus, scleroderma, and Sjogren's syndrome.

Symptoms of Autoimmune Disorders

Autoimmune disorders encompass a range of conditions where the immune system mistakenly attacks healthy cells in the body. Symptoms can vary widely depending on the specific disorder.

Fatigue is a common symptom experienced by many individuals with autoimmune disorders. Joint pain and swelling may occur in conditions like rheumatoid arthritis, while skin rashes can be present in disorders such as lupus or psoriasis.

Some autoimmune disorders may cause recurrent fevers or an overall feeling of unwellness. Hair loss can be a symptom of conditions like alopecia areata, and dry mouth and eyes may be indicative of Sjögren's syndrome.

It's important to note that symptoms can be unpredictable and may flare up periodically.

Test Procedure

The ANA by immunoblot panel involves collecting a blood sample from a vein in the arm using a sterile needle and syringe. A trained technician will clean the area with an antiseptic before inserting the needle to draw blood. The collected sample will then be sent to the laboratory for testing.

The ANA by Immunoblot panel test is a two-step laboratory test that helps in identifying specific autoantibodies present in the blood. It involves running an initial screening test followed by a confirmatory test using a technique called immunoblotting. The immunoblotting technique separates different proteins present in the blood based on their size and then probes them with specific antibodies to identify any autoantibodies present.


A positive result on an ANA by Immunoblot panel suggests the presence of autoantibodies that target nuclear antigens within the body.

Once diagnosed with an autoimmune condition, treatment typically focuses on managing symptoms, reducing inflammation, and preventing damage to affected organs or tissues. The treatment plan may involve a combination of medications, lifestyle modifications, and other therapeutic interventions.

Medications prescribed may include anti-inflammatory drugs, immunosuppressants, or disease-modifying antirheumatic drugs, depending on the specific autoimmune disorder and its severity.

Additionally, lifestyle changes such as stress management, regular exercise, and a balanced diet can play a crucial role in managing autoimmune conditions. Some individuals may also benefit from complementary therapies like acupuncture, yoga, or dietary supplements, although it's important to consult with a doctor before initiating any new treatment approach.

Regular monitoring and follow-up with a healthcare provider are essential to assess treatment efficacy, make necessary adjustments, and ensure the overall well-being of individuals with autoimmune conditions.

Benefits of an Early Diagnosis

Early diagnosis of autoimmune conditions through the ANA by Immunoblot panel is crucial for several reasons.

Firstly, early detection allows for timely intervention and treatment. Autoimmune conditions are chronic and progressive, meaning that symptoms and damage to organs or tissues may worsen over time. By identifying these conditions early, doctors can implement appropriate treatment strategies to manage symptoms, reduce inflammation, and slow down disease progression. Early treatment can help alleviate symptoms, improve quality of life, and prevent or delay the development of complications associated with autoimmune disorders.

Secondly, early diagnosis allows for better monitoring and management of the disease. Autoimmune conditions are characterised by unpredictable flare-ups and remissions. Regular monitoring of the disease activity through follow-up tests, symptom assessment, and clinical evaluation helps doctors adjust treatment plans as needed. This proactive approach can help optimise the management of the condition, minimise disease activity, and prevent long-term complications.

Furthermore, early diagnosis enables patients to make informed decisions and take an active role in their healthcare. It allows individuals to educate themselves about their specific autoimmune condition, understand potential triggers, and make necessary lifestyle modifications to support their overall well-being.

Early diagnosis also empowers patients to seek appropriate support networks, connect with patient advocacy groups, and access resources that can provide information, guidance, and emotional support throughout their journey with the autoimmune condition.

Lastly, early diagnosis may lead to better prognosis and outcomes. Initiating treatment at an early stage of the disease may help prevent or delay irreversible damage to organs or tissues. It can also reduce the risk of complications and co-existing conditions associated with autoimmune disorders. With timely intervention, individuals have a greater chance of achieving disease control, preserving organ function, and maintaining a higher quality of life.

Apollo 24|7 provides easy access to laboratory tests from the comfort of your home. Booking a slot for the ANA by Immunoblot panel test is easy - just visit the website or download the app and select the test you need. A trained technician will come to your doorstep to collect the blood sample, and you will receive the results within 36 hours.

faqFrequently Asked Questions (FAQs)

An autoimmune disorder is a condition in which the immune system mistakenly attacks healthy cells and tissues in the body.
The ANA by Immunoblot Panel can detect a range of autoimmune conditions, including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome, scleroderma, mixed connective tissue disease (MCTD), among others.
Unlike traditional ANA tests that use indirect immunofluorescence (IFA) to detect autoantibodies, the ANA by Immunoblot Panel employs immunoblot technology. It provides a more detailed and specific analysis of the antibodies involved, allowing for accurate identification of autoimmune conditions.
No, a negative result on the ANA by Immunoblot Panel cannot definitively rule out an autoimmune condition. Autoimmune conditions are complex and can have varying presentations. A negative result could mean that the specific autoantibodies tested for were not detected at the time of the test, or the autoantibodies present may not have been included in the panel. Additional tests or further evaluation may be required to confirm or rule out an autoimmune condition.
The ANA by Immunoblot Panel is not typically used as a routine screening test for the general population. It is usually ordered when a doctor suspects an autoimmune condition based on a patient's symptoms, physical examination, or other diagnostic findings.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results