ANTI BETA-2 GLYCOPROTEIN IgM AND IgG in Barrackpore, Kolkata

Anti Beta-2 Glycoprotein IgM and IgG Test: Price, Purpose, Range & Reports

Test Overview

The Anti Beta-2 Glycoprotein IgM and IgG Test is a specialised blood test used to detect autoantibodies that target Beta-2 Glycoprotein I (β2-GPI), a key protein involved in regulating blood clotting. These antibodies are central to the diagnosis of Antiphospholipid Syndrome (APS), an autoimmune disorder that increases the risk of thrombosis and pregnancy complications.

By measuring both IgM and IgG antibody levels, the test helps clinicians identify immune-mediated clotting risks and supports a definitive APS diagnosis. It is commonly ordered for patients with unexplained blood clots, recurrent miscarriages, or autoimmune conditions such as systemic lupus erythematosus (SLE). If you are searching for a reliable Anti Beta-2 Glycoprotein Test price or a convenient test near me, Apollo 24|7 provides accredited laboratory services with timely collection and secure, fast report access.

What is the Anti Beta-2 Glycoprotein IgM and IgG Test?

The Anti Beta-2 Glycoprotein IgM and IgG Test is an immunological blood assay used to detect autoantibodies targeting Beta-2 Glycoprotein I (β2-GPI), a plasma protein that plays a key role in regulating blood clotting. When the immune system mistakenly produces antibodies against β2-GPI, it can lead to a pro-thrombotic state, increasing the risk of abnormal blood clot formation.

This test measures two antibody types: IgG and IgM. IgG is the most clinically relevant for diagnosing Antiphospholipid Syndrome (APS), as it reflects a chronic autoimmune response and is strongly associated with thrombotic events. IgM, while less specific, is typically the first antibody produced during an immune reaction and remains important for comprehensive screening and early detection of APS.

What is the Anti Beta-2 Glycoprotein IgM and IgG Test Price?

The Anti Beta-2 Glycoprotein IgM and IgG Test price reflects the complex, specialised technology required for the quantitative and accurate measurement of these specific antibodies in the blood. The final cost of your test is influenced by several elements:

• Advanced testing methodology: The test uses ELISA (Enzyme-Linked Immunosorbent Assay), a highly sensitive and precise technique that requires specialised equipment and reagents to measure both IgM and IgG antibodies accurately.
• Location and regional costs: Prices may vary depending on the city or region due to differences in operational expenses, laboratory logistics, and supply chain factors.
• Type of service: Choosing home sample collection may add a small service fee to the overall cost.
• Laboratory accreditation: Tests performed at NABL-accredited laboratories ensure high standards of accuracy and reliability, which is especially important for diagnosing serious conditions like APS.
• Membership and discounts: Some diagnostic providers offer reduced rates for members or seasonal discounts, which can lower the overall cost of testing.

To find the most accurate and up-to-date pricing near you, it’s best to check directly with the Apollo 24|7 website or app. Rates are often updated based on location and available offers.

What is the Purpose of the Anti Beta-2 Glycoprotein IgM and IgG Test?

The primary purpose of the Anti Beta-2 Glycoprotein IgM and IgG Test is to provide necessary laboratory evidence for the diagnosis of Antiphospholipid Syndrome (APS), also known as 'Sticky Blood Syndrome'.

Doctors recommend this test for the following key objectives:

• Diagnose Primary or Secondary APS: To confirm the presence of APS, which can occur on its own (primary) or in the context of another autoimmune disease, such as Systemic Lupus Erythematosus (secondary).
• Investigate Thrombosis: To find the underlying cause of unexplained blood clotting in veins (DVT, PE) or arteries (stroke, heart attack), especially in younger patients or those with no conventional risk factors.
• Evaluate Pregnancy Morbidity: To screen women with a history of recurrent, unexplained miscarriages, fetal loss, or other pregnancy complications like severe preeclampsia.
• Risk Stratification: To help doctors assess the overall severity and risk profile of the patient, which guides the necessary treatment with blood-thinning medications.

Who Should Get an Anti Beta-2 Glycoprotein IgM and IgG Test Done?

This test is typically ordered by haematologists, rheumatologists, or obstetricians/gynaecologists when a patient’s symptoms or medical history suggest the possibility of APS.

Doctors may recommend this test in the following situations:

• History of unexplained thrombosis: Individuals who have experienced one or more episodes of blood clots in the legs (deep vein thrombosis), lungs (pulmonary embolism), brain (stroke), or other areas without a clear cause.
• Recurrent pregnancy loss: Women who have had three or more consecutive miscarriages before the 10th week of pregnancy, or one or more fetal deaths after the 10th week, may be evaluated for APS.
• Diagnosis of systemic lupus erythematosus (SLE): Patients with lupus are routinely screened for antiphospholipid antibodies, as APS commonly coexists with SLE.
• Symptoms suggestive of APS: This includes unexplained low platelet counts (thrombocytopenia), livedo reticularis (a lace-like purplish skin rash), or other signs of autoimmune-related clotting disorders.
• Positive results in other antiphospholipid antibody tests: If a patient has tested positive for lupus anticoagulant or anticardiolipin antibodies, this test may be ordered to complete the APS antibody profile.
• Monitoring known APS patients: The test may be used to track antibody levels over time to guide treatment and assess ongoing risk.

Components of the Anti Beta-2 Glycoprotein IgM and IgG Test

This diagnostic test is focused on quantifying two distinct classes of antibodies against the same target protein.

The test is performed for the measurement of:

• Anti Beta-2 Glycoprotein I - IgG: Measures the long-term, chronic antibody response.
• Anti Beta-2 Glycoprotein I - IgM: Measures the short-term, acute antibody response.

Understanding an Anti Beta-2 Glycoprotein IgM and IgG Test Report

The Anti Beta-2 Glycoprotein IgM and IgG Test is a quantitative blood test. Results are typically reported in standard laboratory units (e.g., GPL units/mL for IgG and MPL units/mL for IgM) or sometimes simply categorised.

• Negative Result: Indicates that the antibodies were not detected above the laboratory cut-off threshold. While this makes APS less likely from this marker, the doctor will still consider other markers (like Anticardiolipin and Lupus Anticoagulant).
• Positive Result (Low, Medium, or High): Indicates the presence of the antibodies.

The Requirement for Diagnosis (Persistence)

A positive result is not definitive for APS unless it is confirmed to be persistently positive. This means:

• Initial Event: You have a positive result (usually moderate to high).
• Clinical Event: You have a history of clotting or pregnancy complications.
• Confirmation: The test is repeated after at least 12 weeks (3 months), and the result remains positive.
• Clinical Significance: The higher the concentration (titre), and the more types of antiphospholipid antibodies found (e.g., positive for Lupus Anticoagulant, Anticardiolipin, and Anti Beta-2 Glycoprotein), the higher the patient's risk category for future clotting events.

The result should always be reviewed by a specialist (Haematologist or Rheumatologist) who will determine the appropriate course of action, which often involves prophylactic or therapeutic anticoagulation (blood thinners).

Preparation and Procedure for Anti Beta-2 Glycoprotein IgM and IgG Test

1. How is the Anti Beta-2 Glycoprotein IgM and IgG Test performed?

The test requires a standard venous blood sample collection. A certified phlebotomist will quickly draw a sample of blood, usually from a vein in your arm, using sterile equipment. The blood sample is then processed and sent for quantitative analysis of the antibodies using specialised immunological techniques.

2. Do I need to fast before taking this blood test?

No, fasting is not required for the Anti Beta-2 Glycoprotein IgM and IgG Test. The levels of these specific antibodies are not affected by food or drink intake, so you can take the test at any time of the day without dietary restrictions.

3. Should I stop taking my current medications, especially blood thinners?

You should never stop any prescribed medication without explicit instructions from your ordering physician. It is absolutely critical to inform your doctor and the lab technician about all medications you are currently taking, especially anticoagulants (blood thinners). Your doctor will determine if any temporary pause or adjustment is necessary, as certain treatments could potentially interfere with the test's clinical interpretation.

4. How often might this test need to be repeated?

For the definitive diagnosis of Antiphospholipid Syndrome (APS), a positive result must be confirmed after a period of at least 12 weeks (3 months). Therefore, the test is often repeated once to demonstrate persistence. Additionally, if you are diagnosed with APS, your doctor may repeat the test periodically to monitor disease activity or to re-evaluate your risk profile over time.

Booking Anti Beta-2 Glycoprotein IgM and IgG Test Online & Checking Reports

Apollo 24|7 simplifies the process of obtaining this critical diagnostic test, allowing you to schedule your collection and access your results securely online, ensuring timely communication with your doctor.

A. What are the Steps to Schedule the Test on Apollo 24|7?

1. Visit the Apollo 24|7 website or mobile application and search for the Anti Beta-2 Glycoprotein IgM and IgG Test.
2. Confirm the latest Anti Beta-2 Glycoprotein IgM and IgG Test price for your city and click the 'Book Now' button.
3. Select your preferred date and a convenient time slot for home collection.
4. Complete the secure online payment. Confirmation details and preparation reminders will be sent instantly.

B. How Do I Access My Test Results Online on Apollo 24|7?

1. Log in to your Apollo 24|7 accounts using your registered phone number or email.
2. Navigate to the 'Health Records' or 'My Reports' section on the dashboard.
3. Click on your completed test name to view the detailed report immediately.
4. You can easily view the entire report online or download it in PDF format to share with your physician.

Conclusion

The Anti Beta-2 Glycoprotein IgM and IgG Test is a critical part of the antiphospholipid antibody panel, offering rheumatologists and haematologists precise immunological evidence to support the diagnosis of Antiphospholipid Syndrome (APS). Identifying these autoantibodies is essential, as APS can lead to serious complications such as recurrent thrombosis and pregnancy loss. A confirmed diagnosis has long-term implications for patient care, often requiring the use of anticoagulant therapy to prevent future clotting events. Therefore, the accuracy, sensitivity, and reliability of this test are vital for guiding effective clinical decisions and ensuring optimal patient outcomes.