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Anti-Nmo (Neuromyelitis Optica ) Antibody / Aquaporin 4

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  • Anti-Nmo (Neuromyelitis Optica ) Antibody / Aquaporin 4

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About

blood sample
Sample

CSF/SERUM

Gender
Gender

Both

users
Age group

7 years & above

Neuromyelitis Optica (NMO) is a rare autoimmune disorder that affects the spinal cord and nerves of the eyes. It occurs when your immune system attacks the cells in the central nervous system.

Neuromyelitis Optica can lead to the following health complications:

  • Arm or leg paralysis
  • Blindness in one or both eyes
  • Spasms
  • Uncontrollable hiccups
  • Vomiting
  • Loss of sensation
  • Problem with walking

This condition is detected by analysing the aquaporin 4 receptor in the bloodstream.

If you notice one or more of the following symptoms, ensure that you approach the doctor and undergo an NMO antibody test:

  • Faded appearance of colours
  • Sharp or burning pain in the arms and legs
  • Tight muscle spasms
  • Weakness in the arms and legs
  • Swollen spinal cord
  • Optic neuritis
  • Loss of vision

Notably, these symptoms can be mild or severe, varying from person to person. Hence, proper diagnosis through an anti-aquaporin 4 test becomes crucial.

To diagnose NMO, it is crucial to identify the presence of AQP4 antibodies in your system. Detecting serum antibodies in the blood can work as a marker to identify Neuromyelitis Optica. Hence, your doctor may recommend an Anti-NMO (Neuromyelitis Optica) Antibody/Aquaporin 4 Test.

In routine screening, the detection of NMO IgG antibodies can serve as a base for understanding the severity of Neuromyelitis Optica. However, an aquaporin blood test can prove more effective in proper medical evaluation.

The NMO antibody test measures the presence and quantity of AQP4 antibodies in your blood serum. For this purpose, you need to provide your blood specimen through the process of venepuncture.

The Anti-NMO (Neuromyelitis Optica) Antibody/Aquaporin 4 Test is similar to other blood-based assessments. During the process, a lab technician draws blood from a vein in your arm. You do not need to follow any other special preparations for this test. However, informing your doctor about any existing medical conditions and symptoms is a good idea. A positive aquaporin blood test result indicates that you have this rare condition.

It is essential to know that the values of the aquaporin 4 receptor change during the course of the disease. Depending on your condition, the doctor can recommend the following treatments:

  • Steroids
  • Physiotherapy
  • Medicines like azathioprine

Proper diagnosis of this condition is essential for timely treatment. Hence, choosing a reliable pathology lab that offers a specialised anti-aquaporin 4 test becomes vital. Apollo 24|7 provides testing for NMO at competitive rates. You can thus avail this testing after proper recommendations from your doctor. 

faqFrequently Asked Questions (FAQs)

Is Neuromyelitis Optica a terminal disease?

NMO can impact different people in distinct ways. The symptoms can also vary in intensity. Hence, it is not easy to gauge the impact of this autoimmune condition on your body. However, it is possible to live for many years if you receive prompt treatment after the onset of this illness. Hence, it is crucial to undergo an NMO IgG or aquaporin blood test to confirm this condition.

What are some common medicines for NMO?

Your doctor can prescribe drugs like Rituxan, prednisone, methotrexate, and Azasan to prevent attacks due to NMO. In addition, you might also require high-dose corticosteroids or intravenous treatment to control the symptoms.

How to deal with NMO?

At present, there is no established cure for this fatal condition. However, if you test positive for AQP4 antibodies, it is crucial to consume steroids and follow the doctor’s advice to prevent future relapses. Slowing this disease’s progression is a well-known way to deal effectively.

Can you inherit Neuromyelitis Optica?

In most cases, inheriting NMO is not possible. However, you can have a chance to deal with this condition due to a family history of autoimmune disorders. In such cases, it is vital to undergo testing as soon as you notice the symptoms.

Is NMO more severe than multiple sclerosis?

The individual symptoms of NMO are more lethal and painful than multiple sclerosis. Since this disease impacts the central nervous system, you have to deal with serious complications. However, the occurrence of such a condition is quite rare.

Can you prevent NMO relapses?

It is possible to follow physiotherapy and consume specific drugs to prevent relapses of NMO. Your doctor can suggest using monoclonal antibodies as part of a treatment to prevent such relapses. You can also have one mild episode of this disease without any relapses. Hence, the impact of NMO is quite subjective.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results