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Anti Nuclear Antibody / Factor (ANA / ANF), IFA (Hep-2) Reflex To ANA Profile in Rtc Colony, Hyderabad

Also Known as ANA Screening, Autoimmune

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  • Anti Nuclear Antibody / Factor (ANA / ANF), IFA (Hep-2) Reflex To ANA Profile

    6 tests included

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*Optional Tests: Testing of these is conditional depending on results of other tests

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Sample

BLOOD

Gender
Gender

Both

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Age group

7 years & above

The body’s immune system is responsible for keeping it safe and protected in the face of all adverse infections and diseases. When a foreign substance like bacteria or virus invades your body, the immune system reacts to it by producing antibodies. These antibodies fight against the infection.

Sometimes, the immune system produces antinuclear antibodies (ANA), which proactively work against the body's tissues. It targets every cell's nucleus.

The healthcare provider will likely prescribe an ANA test to determine the level of antinuclear antibodies in the blood. It will offer an insight as to whether the immune system is attacking the body or not.

Moreover, it will also help detect or rule out specific suspected autoimmune diseases.

These autoimmune disorders may include the following:

  • Lupus: It is an autoimmune disorder wherein the immune system attacks the body's organs and tissues. It leads to inflammation in different body parts such as skin, joints, blood cells, lungs, kidneys, heart and brain. One of its most distinctive symptoms is a facial rash.
  • Rheumatoid arthritis: Rheumatoid arthritis is another autoimmune disorder which causes damage to the joints. It severely impacts the inner lining of your joints, leading to excessive swelling, inflammation and pain that might eventually cause joint deformity and bone erosion. 
  • Scleroderma: Also known as systemic sclerosis, scleroderma is a collective group of rare illnesses which involve the tightening and hardening of the skin. It may also cause damage to your digestive tract, internal organs and blood vessels. Its symptoms range from skin-related signs to digestive, lung and heart problems.

ANA test may not necessarily confirm one specific diagnosis, but it can still rule out other diseases. If the test is positive, the doctor may further test your blood for particular antinuclear antibodies, indicating specific conditions.

The ANA test majorly checks for the following four elements:

  • Antinuclear antibody: It checks for the presence of antinuclear antibodies. If your blood shows the presence of the same, it could indicate certain autoimmune conditions. 
  • Fluorescence intensity: This element tests for the quantity or the intensity of the fluorescence or antinuclear antibody in the blood.
  • Fluorescence pattern: This tests the antinuclear antibody fluorescence pattern in the blood. 
  • Estimated titer: The ANA test result generally comes in either pattern, level or titer. An estimated titer of 1:40 is considered positive for antinuclear antibodies. If you test positive for autoimmune disease, this level will be higher.

Apollo 24|7 offers a quick and effortless ANA test with the test results produced within a week. Getting an ANA test will help:

  • Ascertain if your symptoms are because of an autoimmune disorder or not
  • Determine if you do suffer from an autoimmune disease, such as lupus, Sjogren's disease, scleroderma, Raynaud's phenomenon or mixed connective tissue disease
  • Devise the further steps to help with effective treatment of the autoimmune disorders
     

faqFrequently Asked Questions (FAQs)

ANA test cannot diagnose one specific autoimmune disease. But a positive ANA test result can indicate a positive association with one of the following medical conditions: Systemic lupus erythematosus Autoimmune hepatitis Sjogren’s disease Rheumatoid arthritis Autoimmune thyroid disease Scleroderma Dermatomyositis or polymyositis
Symptoms of any autoimmune disorder may require an ANA test to be taken by the affected person. Some of the general symptoms include: Muscle pain Joint swelling and pain Extreme fatigue Red rash in the shape of a butterfly (generally a sign of lupus) Fever and chills
Systemic lupus erythematosus is one of the most common autoimmune disorders that the ANA test can help determine. The severity of its symptoms may vary from mild to extreme, depending on the severity of the disorder. You may notice the following symptoms: Pain and swelling in joints Extreme loss of energy and fatigue Confusion, forgetfulness and memory troubles Red skin rash on the face
Once ANA test results confirm lupus, your doctor may suggest several drugs and pain relievers to help with the symptoms. Some of these would include: Immunosuppressive drugs Corticosteroids  Chloroquine or hydroxychloroquine
Rheumatoid arthritis may show up in different signs and symptoms, such as: Swollen, warm and tender joints Fatigue, loss of appetite and fever Stiffness in joints, especially in the morning or after a state of inactivity ANA test results may come in handy to confirm the diagnosis of rheumatoid arthritis, validating these symptoms.
If left untreated, scleroderma can cause a range of complications, such as: Damage to fingertip tissues, skin sores Scarring of tissues in the lung Scleroderma renal crisis or kidney failure Scarring of tissues in the heart, abnormal heart rate and congestive heart failure Tightening of skin  Dental decay Restricted joint flexibility Digestive troubles like cramps, constipation, bloating and diarrhoea

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results