Anti Sperm Anti Bodies

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Effective price: ₹1581

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    blood sample




    Age group

    Above 10 years

    Antisperm antibodies are immune system proteins that fight sperm. They are also responsible for destroying it as they are produced sperm is considered as an invader and triggers a defence response. Antisperm antibodies are generally found in blood, semen, or vaginal fluids.

    When an individual is tested positive for antisperm antibodies, their presence can negatively impact their fertility. An individual may experience motility, sperm count reduction, and effects on sperm-egg interaction.

    In men, antisperm antibodies are produced after there is an injury to the testicles or after surgery has been performed on them. These antibodies can also be produced when the barrier between separating the sperm from the immune system (blood-testis barrier) is broken. Due to this, the sperm reaches the immune system, and antisperm antibodies form.

    The leading cause of antisperm antibodies is vasectomies. According to medical studies and research, around 50% of men with vasectomies develop antisperm antibodies. While in other cases of vasovasostomies, the occurrence of antisperm antibodies is not always reduced. Additionally, other surgeries such as testicular biopsies can also lead to antisperm antibodies.

    Trauma caused by testicular torsion or prostate infection can also cause the production of antisperm antibodies in men. Prostate infection leads to anti- as well as pro-oxidative factor imbalance in male semen. Because of this, antisperm antibodies are formed.

    In women, antisperm antibodies are found in the reproductive system. They are usually produced when the female body reacts to sperm as though it were an invader. This leads to an allergic reaction-like response. Some conditions may increase the risks and possibilities of developing antisperm antibodies in women.

    The formation of these antisperm antibodies can contribute to infertility in both men and women. 
    Anti-sperm antibodies test is a valuable step in providing substantial information about fertility. At Apollo 24|7, you can opt for an antisperm antibodies test if you face any of the following symptoms:

    • If you experience unexplained infertility
    • In cases of sperm agglutination or sticking together of sperms 
    • People with in vitro fertilisation

    If you are having a challenging time getting pregnant with your partner, you may appear for an anti-sperm antibodies test to check for their presence. Treatment may differ for men and women. For men, healthcare providers or doctors may prescribe medication to lower the body's immune response.

    For women, intrauterine insemination is one treatment method that has shown promising results. 

    faqFrequently Asked Questions (FAQs)

    Frequently asked questions

    The type of treatment for antisperm antibodies varies on the level of antibodies present in your body. If you have lower anti-sperm antibodies levels, you may have no significant effect on your fertility rate. However, if you have high anti-sperm antibodies levels, then the suitable treatment is intra-cytoplasmic sperm injection (ICSI).
    With the production of antisperm antibodies in men, fertility can be severely impacted by reduced sperm quality, count, and motility. Due to this, fertilisation does not occur as the sperm does not reach its destination. When antisperm antibodies are present in women, the sperm is destroyed and cannot reach the egg. Hence, the fertilisation process is disrupted.
    Antisperm antibodies test is needed when your body becomes sensitised to sperm. This results in an immune system response that destroys the sperm. The test looks closely at specific proteins or antibodies capable of fighting against a man's sperm in the semen and blood. Higher levels of antibodies in the semen can lower the chance of fertilisation.
    Before appearing for an anti-sperm antibodies test, an individual must talk to their doctor or healthcare provider regarding any concerns about the test. Usually, the doctors or healthcare providers give adequate information regarding sample collection. Male patients are advised not to release their sperm for up to two days before appearing for the test.
    It is possible for women also to develop antibodies to their partner's sperm. While the methods to detect antisperm antibodies are relatively simple, preventing their effects is not very easy. The only method or treatment to prevent it is through in-vitro fertilisation (IVF) or intra-cytoplasmic sperm injection (ICSI).
    In most cases, antisperm antibodies can form inside your semen when your immune system undergoes exposure to large quantities of sperm by breaking the blood-testes barrier.

    Why should Apollo be your preferred healthcare partner?

    • 40 Years of legacy and credibility in the healthcare industry.
    • NABL certified multi-channel digital healthcare platform.
    • Affordable diagnostic solutions with timely and accurate test results.
    • Up to 60% discount on Doorstep Diagnostic Tests, Home Sample Collection.
    • An inventory of over 100+ laboratories, spread across the country, operating out of 120+ cities with 1200+ collection centers, serving over 1800+ pin codes.

    The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results