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Beta-2- Glycoprotein -1 IgA

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  • Beta-2- Glycoprotein -1 IgA

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About

blood sample
Sample

BLOOD

Gender
Gender

Both

users
Age group

7 years & above

The beta-2 glycoprotein-1 antibody is an autoantibody that is related to improper blood clotting. The immune system creates these antibodies when it mistakes the body’s lipid proteins (phospholipids) for an invader. They are usually present in the cell membranes and platelets of the body and ensure proper blood clotting.

These antibodies, also called antiphospholipid antibodies, may enhance the risk of inappropriate blood clots in the arteries and veins. Due to this, they are used as markers to detect an autoimmune condition called antiphospholipid syndrome (APS). It is an immune system disorder that may further give rise to conditions like:

  • Deep vein thrombosis, a blood clot occurring in the leg.
  • Arterial thrombosis, a lump in the artery that might lead to strokes or heart attacks.
  • Blood clots in the brain, impacting standard functions like mobility, balance, vision, speech, and memory.

It is also more likely to cause miscarriages in pregnant women. Hence, diagnosing this disorder is vital. It is associated with symptoms like tiredness, numbness, and tingling in different body parts.

The beta-2-glycoprotein-1 IgA test is a diagnostic method to determine if a patient suffers from antiphospholipid syndrome. It can assist in detecting the reason for the occurrence of abnormal blood clots in the body. This test also helps determine the cause of recent miscarriages in women.

The procedure for the beta-2 glycoprotein-1 IgA test is similar to a standard blood test. The clinical lab technician draws blood from the vein in the arm and stores it in a labelled container. The lab conducts further analysis to determine if there are beta-2-glycoprotein-1 antibodies present in the blood.

If the beta-2-glycoprotein-1 IgA test results are positive, it might indicate the presence of APS. Negative results may not entirely rule out APS since there might be other antibodies contributing to the condition.

Moreover, these antibodies might be temporarily present inside a patient at times due to conditions like acute infections, HIV/AIDS, or some cancers. Some drugs like penicillin, procainamide, and phenytoin may also induce temporary beta-2-glycoprotein-1 antibodies.

Apollo 24|7 offers a comprehensive beta-2-glycoprotein-1 IgA test to determine the reason for irregular blood clotting. Following are some symptoms that might compel a doctor to recommend the beta-2-glycoprotein-1 IgA test:

  • Balance and mobility problems.
  • Fatigue (extreme tiredness).
  • A tingling sensation or pins and needles in the arms or legs.
  • Repeated headaches or migraines.
  • Speech and memory problems.
  • Vision problems, such as double vision.

If one or more of these symptoms are persistently present, it is vital to consult a doctor to understand and address the issue. The doctor might suggest a beta-2-glycoprotein-1 IgA test, depending on the onset and severity of these symptoms. 
 

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faqFrequently Asked Questions (FAQs)

Frequently asked questions

Miscarriages may occur in women suffering from antiphospholipid syndrome (APS). This condition increases the risk of miscarriage in the third semester of pregnancy. Hence, it is essential to consult a doctor to get the beta-2-glycoprotein-1 IgA test performed to gauge the condition early and devise a treatment plan.
The beta-2-glycoprotein-1 IgA test helps detect the presence of corresponding antibodies that are associated with APS. If there are increased levels of the beta-2-glycoprotein-1 antibodies in the blood, you might have APS. A negative result might indicate the presence of temporary antibodies in the blood due to certain disorders or medication.
The antiphospholipid syndrome (APS) can lead to several pregnancy complications, such as: Stillbirth Premature birth Placenta complications Foetal growth restrictions In severe cases, it may also result in a miscarriage.
The beta-2-glycoprotein-1 IgA test is a standard blood test with minimal to no complications. You might encounter slight bruising at the spot where the clinical lab assistant draws blood. However, the bruising fades away without any external intervention.
At present, there is no cure for antiphospholipid syndrome. However, various methods exist to treat and regulate it once it affects a patient. The medications can assist in preventing blood clots and miscarriages.
Antiphospholipid syndrome is usually found in people with autoimmune diseases such as lupus. It is also widely prevalent in individuals suffering from rheumatic disorders that affect their joints or bones. Females are also more likely to contract this condition compared to males.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results