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Beta-2- Glycoprotein -1 IgM

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blood sample
Sample

BLOOD

Gender
Gender

Both

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Age group

7 years & above

Some individuals suffer from autoimmune disorders in which the body’s immune system becomes overactive and starts attacking healthy tissues. Common examples of such conditions include antiphospholipid syndrome (APS), celiac disease, multiple sclerosis, and Addison disease.

The autoantibodies associated with a molecule called beta 2 glycoproteins can lead to severe blood clotting. Generally, symptoms of APS signify the presence of beta 2 glycoprotein antibodies in your bloodstream. These autoantibodies target the body’s lipid proteins on cell membranes and platelets.

Complications arising from such a condition are as follows:

  • Recurrent miscarriages
  • Cardiovascular problems
  • Decreased blood flow to kidneys
  • Problems with pregnancies

Hence, it is crucial to identify the presence of such antibodies to control diseases like APS. After proper evaluation, your doctor can recommend a beta 2 glycoprotein test for this purpose.

In most cases, unexplained blood clotting is a common sign of the onset of beta 2 glycoprotein antibodies impact. There are three classes of such antibodies:

  • Immunoglobulin M (IgM)
  • Immunoglobulin G (IgG)
  • Immunoglobulin A (IgA)

The IgM antibodies are the first proteins produced during an immune response. Hence, the beta 2 glycoprotein 1 IgM test aims to identify the presence and quantity of these antibodies. 
A glycoprotein IgM positive result and APS symptoms signify the possibility of autoimmune disorders.

However, higher values of beta 2 glycoprotein antibodies indicate the presence of the antiphospholipid syndrome. In such a case, your doctor can recommend another test after twelve weeks to confirm the syndrome.

Like a simple blood test, this diagnostic evaluation does not require any special preparation. The lab technician follows a process called venipuncture. In this testing, the professional draws blood from a vein in your arm using a syringe. This specimen is vital to detect IgM antibodies.

It is crucial to realise that the test reports can have multiple outcomes as follows:

  • High level of anti-beta 2 glycoprotein antibodies (Initial and post-twelve-week period): Most likely occurrence of APS
  • Negative anti-beta 2 glycoprotein but positive antiphospholipid antibodies: Likely existence of APS
  • Weak to moderate antibody count: Likely existence of other conditions
  • Negative results: Acute infection

Depending on your reports, the doctor can properly assess the condition. Hence, choosing a professional lab offering the beta 2 glycoprotein 1 IgM test proves crucial. Timely detection of these antibodies can lead to adequate initialisation of the treatment. However, proper assessment of the blood clotting symptoms is very important.

Apollo 24|7 offers this blood test at competitive prices. We ensure strict adherence to all medical requirements while conducting this assessment. Conditions like APS do not have a cure. Still, you can control further complications and blood clots through timely diagnosis and suggested medications. 
 

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faqFrequently Asked Questions (FAQs)

In large quantities, you should avoid foods like Brussel sprouts, cabbage, avocado, garbanzo beans, etc. In addition, regular intake of prescribed medicines is the key to controlling the clotting symptom of APS. Ensure that you choose a reliable lab to increase your chances of more accurately detecting the glycoprotein IgM positive result.
The chances of APS conversion into lupus or other similar disease are unusual. You can control the ill-effect of APS by taking medicines like warfarin and other prescribed blood thinners. Early detection of APS through beta 2 glycoprotein 1 IgM test is essential to start the treatment in time.
If you suffer from APS, a condition resulting due to autoantibodies, it is crucial to consume a balanced diet. Aim for low-fat dairy products, proteins, and lots of fruits. You should also pay equal attention to consuming good carbohydrates and maintaining a healthy weight.
Generally, the antiphospholipid syndrome is not a result of genetic factors. You can, however, suffer from this uncommon condition if a family member had antiphospholipid autoantibodies. This condition can also lead to fatigue, confusion, and forgetfulness.
The beta 2 glycoprotein 1 is associated with the regulation of blood coagulation. It is also known to inhibit the intrinsic coagulation pathway. A beta 2 glycoprotein test is necessary to assess the proper functioning of this molecule. Hence, undergo this testing without fail if you notice symptoms like recurrent miscarriages, chest pain, or low platelet count.
Miscarriages from APS occur during the early pregnancy period. The autoantibodies inhibit the proper growth of foetal cells and prevent normal pregnancy. Hence, this condition can lead to unfortunate miscarriages in women.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results