C. DIFFICILE TOXIN A & B AND GDH, STOOL in Central Secretariat, Hyderabad

The C. Difficile Toxin A & B and GDH, Stool Test is conducted to detect the presence of Clostridium difficile (C. difficile) toxins and glutamate dehydrogenase (GDH) in the individual's stool sample. C. difficile infection is a bacterial infection that causes inflammation of the colon, leading to symptoms like diarrhoea and abdominal pain. This test helps in the diagnosis of this infection, which is a common cause of antibiotic-induced diarrhoea. 
Some common symptoms of C. difficile infection that prompt the need for this test are: 
Loose motion 
Abdominal pain and cramping 
Fever 
Loss of appetite 
Nausea 
Fatigue 
To perform the Clostridium difficile toxin test, a small stool sample is required. The sample can be collected at home in a clean container provided by the laboratory. It is important to avoid contamination with urine or water during sample collection. The stool sample is processed in the laboratory to detect the presence of C. difficile toxins A & B and GDH. The presence of toxins A and B produced by C. difficile is checked using a specialised laboratory test. The presence of GDH, an enzyme produced by C. difficile, is detected using an immunoassay. 
If the Clostridium difficile toxin test results are positive, it indicates the presence of C. difficile bacteria. The primary treatment for C. difficile infection involves the use of antibiotics targeted against the bacteria. In some cases, supportive care such as fluid replacement may also be required.
Some benefits of opting for the test early, include: 
Accurate treatment: Early diagnosis of C. difficile infection allows for the timely initiation of appropriate treatment, which can help improve patient outcomes. 
Preventing spread: Early detection helps in implementing necessary infection control measures to prevent the spread of the bacteria to other organs. 
Reduced complications: Prompt treatment can help prevent complications associated with C. difficile infection, such as severe diarrhoea, dehydration, and colon inflammation.