CELIAC PROFILE (TTG IGA ABS, GLIADIN IGG & IGA ABS) in Lucknow

Celiac Profile Test: Price, Purpose, Range & Reports

The Celiac Profile Test is a specialised blood panel used to screen for and diagnose Celiac Disease, a chronic autoimmune disorder. Celiac Disease causes the immune system to react to the gluten protein found in wheat, barley, and rye, leading to the production of specific autoantibodies. Detection of these markers, particularly Tissue Transglutaminase (tTG) IgA, strongly suggests an active autoimmune response that is damaging the small intestine, resulting in nutrient malabsorption. 

Also known as the Celiac Disease Antibody Panel, Gluten Sensitivity Panel, or Gluten Antibody Test, this profile is a critical, non-invasive step required before an intestinal biopsy is considered for definitive diagnosis. If you are searching for a reliable Celiac Profile Test price or a convenient test near me, Apollo 24|7 provides accredited laboratory services with timely collection and secure, fast report access.

What is the Celiac Profile Test?

The Celiac Profile Test is a simple blood test that helps your doctor find out if you have Celiac Disease. When someone with Celiac Disease eats gluten (a protein found in wheat, barley, and rye), their body launches an immune attack against the small intestine. This attack creates special defence proteins called autoantibodies. The test measures the levels of these autoantibodies, the most important one being the Tissue Transglutaminase (tTG) IgA, which serves as strong evidence of the disease.

The Celiac Profile checks for several different types of antibodies to ensure the result is accurate. It also includes an important safety check: the Total IgA Level. This check is critical because some people naturally have low IgA levels, which can make the main tTG-IgA test unreliable. By looking at all these markers together, the test gives a complete picture and helps doctors avoid false negative results.

What is the Celiac Profile Test Price?

The Celiac Profile Test price is representative of the specialised multi-component immunoassay panel used to accurately screen for Celiac Disease. The final cost of your test is influenced by several elements:

•    Technology Used: The test relies on accurate Enzyme-Linked Immunosorbent Assay (ELISA) technology to measure multiple distinct antibodies (IgA and IgG), which contributes to the precision and value of the profile.
•    Location: Prices may differ slightly between cities and regions due to variances in local operating costs and logistical factors.
•    Lab Accreditation: Tests conducted at accredited laboratories, such as those operated by Apollo, ensure adherence to high-quality standards, which are vital for reliable autoimmune screening results.

If you're trying to find the most accurate and affordable Celiac Profile Test price near me, the easiest way is to check the Apollo 24|7 website or app. They update prices regularly based on your location, so you’ll always see the latest rates and any available offers. 

What is the Purpose of the Celiac Profile Test?

The primary purpose of the Celiac Profile Test is the comprehensive and definitive diagnosis of Celiac Disease.

•    Screening and Diagnosis: It is the first line of diagnostic testing for patients presenting with symptoms indicative of Celiac Disease.
•    Identifying High-Risk Individuals: Used for screening first-degree relatives of Celiac patients, who have a significantly higher genetic risk.
•    Differential Diagnosis: Helps distinguish Celiac Disease from other gluten-related disorders (like Non-Celiac Gluten Sensitivity) or other intestinal issues (like Irritable Bowel Syndrome).
•    Pre-Endoscopy Confirmation: A positive result provides strong evidence, often prompting the necessary follow-up small bowel biopsy to confirm the intestinal damage (villous atrophy).

Who Should Get a Celiac Profile Test Done?

The Celiac Profile Test is recommended for anyone (child or adult) who shows signs of celiac disease or has known risk factors. Celiac disease can affect more than just the digestive system, so symptoms may vary widely.

•    Ongoing digestive issues like diarrhoea, constipation, bloating, stomach pain, or unexplained weight loss
•    Nutritional deficiencies such as low iron, vitamin D, or folate, without a clear cause
•    Conditions that are commonly linked to celiac disease, including Type 1 Diabetes, autoimmune thyroid disease, Down syndrome, Turner syndrome, or Addison’s disease
•    A skin condition called dermatitis herpetiformis, which causes itchy, blistering rashes
•    A close family member (parent, sibling, or child) who has been diagnosed with celiac disease
If any of these apply to you, talk to your doctor about whether a Celiac Profile Test is appropriate. Early testing can lead to timely treatment and help prevent long-term complications.

Components of the Celiac Profile Test

The Celiac Profile Test is designed to detect immune responses that suggest celiac disease. It includes several key markers, each with a specific role in helping doctors make an accurate diagnosis:

1. Tissue Transglutaminase (tTG) IgA
This is the primary marker for active celiac disease. It identifies antibodies that target the tTG enzyme in the small intestine. A high level of tTG IgA is strongly linked to intestinal damage caused by gluten exposure.

2. Gliadin Antibodies (IgA and IgG)
These antibodies react to gliadin, a protein found in gluten.
•    Gliadin IgA may appear in early or mild cases and supports the diagnosis.
•    Gliadin IgG is especially useful for patients with IgA deficiency or for young children, as it can detect immune activity even when IgA-based tests are unreliable.

3. Total IgA Level
This acts as a built-in control. It measures the overall amount of IgA in the blood. If Total IgA is low, it may cause false-negative results in IgA-based tests. In such cases, doctors rely more on IgG markers to assess the likelihood of celiac disease.

Together, these components offer a comprehensive view of how the immune system is responding to gluten, helping guide further testing and treatment decisions.

Understanding a Celiac Profile Test Report

Interpreting the Celiac Profile requires looking at the pattern of results, especially the tTG IgA and the Total IgA.

Important Note:
•    Gluten Challenge is Crucial: For the results of this profile to be accurate, the patient MUST have been consuming gluten regularly (daily intake equivalent to at least four slices of bread) for at least 4-8 weeks before the blood draw. Testing while on a strict gluten-free diet can lead to a false negative result, regardless of the diagnosis.
•    Biopsy Confirmation: A positive blood test is highly indicative, but the definitive diagnosis of Celiac Disease traditionally requires a small intestinal biopsy showing characteristic damage.

Preparation and Procedure for Celiac Profile Test

The Celiac Profile test is a simple blood test, but the key to accurate results lies in dietary compliance.

1. How is the Test Done?
A healthcare professional will draw a blood sample from a vein in your arm (venipuncture). The sample is processed to separate the serum, which is then analysed in the laboratory to measure the concentration of the three primary autoantibodies and the Total IgA level.

2. Is Fasting Required?
No fasting is needed for this test. You can eat and drink normally before your appointment.

3. What Time of Day Should I Take the Test?
There’s no specific time requirement. Antibody levels are stable throughout the day.

4. Dietary Requirement (CRITICAL)
You must be following a normal, gluten-containing diet (including wheat, barley, and rye) for several weeks prior to the test. If you have been strictly gluten-free, consult your doctor about performing a "gluten challenge" before the test.

Booking Celiac Profile Test Online & Checking Reports

Apollo 24|7 offers a seamless process for scheduling this important test and accessing your results.

A. How to Schedule the Test on Apollo 24|7

•    Visit the Apollo 24|7 platform and search for Celiac Profile Test.
•    Review the latest Celiac Profile Test price for your location and click 'Book Now'.
•    Select a convenient date and time for the sample collection at the designated facility/lab centre.
•    Complete the secure online payment to confirm your booking.

B. How to Access Your Test Results Online

•    Log in to your Apollo 24|7 account via the website or mobile app.
•    Navigate to the 'Health Records' or 'My Reports' section.
•    Click on the completed Celiac Profile Test report.
•    You can view and download the detailed report in PDF format, which must be shared with your gastroenterologist or physician for interpretation and next steps.

Conclusion

The Celiac Profile Test is a key step in diagnosing celiac disease, an autoimmune condition triggered by gluten. By measuring a combination of antibodies, this test helps doctors understand whether the immune system is reacting abnormally to gluten and potentially damaging the small intestine. For the test to be reliable, it’s important that the person is consuming gluten regularly before the blood sample is taken. If celiac disease is confirmed, switching to a strict gluten-free diet is the only effective treatment. This allows the intestine to heal, improves nutrient absorption, and helps prevent long-term complications. Early diagnosis and dietary changes can significantly improve a person’s health and quality of life.
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